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Structural Biology PhD Projects, Programs & Scholarships in Manchester

We have 27 Structural Biology PhD Projects, Programs & Scholarships in Manchester

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  British Heart Foundation 4-Year PhD Studentships 2020

Funding Type

PhD Type

British Heart Foundation 4-Year PhD Studentships 2020. Our British Heart Foundation (BHF) 4-year PhD programme provides tailored doctoral training for postgraduate students with an interest in cardiovascular sciences.
  (MRC DTP) The impact of centronuclear myopathy mutations in BIN1 on muscle function and structural organisation
  Prof A Trafford, Dr K Dibb, Dr C Pinali
Application Deadline: 15 November 2019

Funding Type

PhD Type

Transverse tubules are surface membrane invaginations in skeletal and cardiac muscle.
  A step change in the modelling of enzymatic catalysis
  Prof P Popelier, Dr L Johannissen
Applications accepted all year round

Funding Type

PhD Type

A deep understanding of enzymatic processes requires an atomic-level description, which is often beyond experimental techniques but achievable through synergy with computational chemistry.
  (MRC DTP) Understanding the mechanisms responsible for aberrant atrial calcium handling in heart failure
  Dr K Dibb, Prof A Trafford, Dr C Pinali
Application Deadline: 15 November 2019

Funding Type

PhD Type

Atrial fibrillation (AF) is the most common cardiac arrhythmia, expected to affect ~18 million Europeans by 2060. AF often occurs in patients with heart failure (HF), increasing their risk of death by ~2 fold.
  (MRC DTP) Design and synthesis of new antivirulence drugs for treatment of tuberculosis
  Dr L Tabernero, Dr S Butterworth, Prof D Procter
Application Deadline: 15 November 2019

Funding Type

PhD Type

Tuberculosis (TB) remains a major health problem that affects billions of people worldwide and the emergence of severe anti microbial resistance (AMR) to current antibiotics is now the main challenge to eradicate the disease.
  (MRC DTP) Using super-resolution microscopy to understand immune cell inhibitory receptors and develop novel immune therapies
  Prof D Davis, Dr J Honeychurch
Application Deadline: 15 November 2019

Funding Type

PhD Type

Super-resolution microscopy allows us to study immune cell activity in unprecedented detail. Recently, Davis’s research team has used these microscopes to study the changing arrangements of molecules on the surface of immune cells as they survey other cells for signs of disease.
  (MRC DTP) Development of antifungal agents that target essential protein kinases in A. fumigatus
  Dr M Bromley, Dr L Tabernero
Application Deadline: 15 November 2019

Funding Type

PhD Type

A. fumigatus is the primary etiological agent of invasive aspergillosis, a disease that primarily affects individuals who are immunocompromised, and causes 200k life threatening infections annually.
  The chemical glycobiology of carbohydrate metabolism
  Prof R Field, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Carbohydrates are widespread in nature and fulfil many important biological functions. However, the biology of carbohydrates is much less well explored than that of nucleic acids and proteins.
  The chemistry and biophysics of phosphoryl transfer enzymes
  Prof J Waltho, Dr A Almond
Applications accepted all year round

Funding Type

PhD Type

One of the most remarkable features of the chemistry of living organisms is the evolutionary utilisation of phosphate esters to provide biopolymers that encode genetic information, deliver temporal protein regulation, generate and distribute free energy throughout the cell, and to provide a ubiquitous handle for metabolic intermediates.
  Assessing the Behaviour of Endotoxin in Biopharmaceutical Formulations: towards creating improved medicines
  Dr A Golovanov
Application Deadline: 15 November 2019

Funding Type

PhD Type

Supervisors. Dr Alexander Golovanov (The University of Manchester) and Dr Adrian Podmore (AstraZeneca). Biopharmaceuticals are the fastest-growing type of treatments for wide range of diseases, with enormous potential for personalised medicine.
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