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Structural Biology PhD Projects, Programs & Scholarships in Manchester

We have 21 Structural Biology PhD Projects, Programs & Scholarships in Manchester

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Showing 1 to 10 of 21
  Maternal anti-hypertensive medicines & placental vascular function
  Dr P Brownbill, Dr J Myers, Dr E Johnstone
Applications accepted all year round
A range of anti-hypertensive medicines are prescribed to women with chronic hypertension in pregnancy, that enter the fetal circulation.
  New NMR tools for the most complex problems
  Dr L Castañar Acedo, Prof GA Morris, Prof M Nilsson
Application Deadline: 19 May 2019
Knowing the structures and behaviour of molecules is crucial for understanding the world around us and for the development of new chemical products, drugs and materials.
  Biochemical elucidation of the novel ECP bacterial stress response
  Dr N Dixon, Prof R Breitling
Application Deadline: 30 April 2019
This PhD project will focus on the detailed elucidation of the biochemical mechanism of a recently discovered gene regulatory network in bacteria.
  Exploration of sub-diffusive motion in high-value polymers
  Dr A Almond, Prof J Waltho
Applications accepted all year round
Complex and potentially high-value polymers have been found to possess anomalous sub-diffusive motion, which has not yet been fully explained.
  Proteomic approach to understand mitochondrial quality control under normal and stress conditions
  Dr H Lu, Prof S Hubbard
Applications accepted all year round
Defects in protein quality control lead to the accumulation of misfolded and damaged proteins, which play an important role in many diseases (e.g.
  The mechanism of gating and transport of pentameric Magnesium ion channels
  Dr S M Prince, Prof R Ford
Applications accepted all year round
Magnesium ions are a co-factor in many important biological processes particularly because of the requirement for Mg2+ in the hydrolysis of Adenosine tri-phosphate, the ubiquitous cellular energy source.
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round
In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
  Ion channel clustering in neuronal membranes
  Dr S M Prince, Prof R Ford
Applications accepted all year round
The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions.
  The effect of differential glycosylation on human recombinant protein secretion, function and clearance
  Dr A Almond, Prof A J Dickson, Dr J Warwicker
Applications accepted all year round
This project aims to investigate the effect of glycosylation on the secretion, physical properties, and functional biological and physiological properties of human recombinant proteins.
  How does fibrillin regulate TGFβ latency and activation?
  Prof C Baldock, Dr A Roseman
Applications accepted all year round
Fibrillin microfibrils are an essential component of our connective tissues and they give tissues such as lung, skin and blood vessels their elasticity.
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