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Medical / Clinical Science (membrane) PhD Projects, Programs & Scholarships

We have 13 Medical / Clinical Science (membrane) PhD Projects, Programs & Scholarships

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  Complement resistance mechanisms by multi-drug resistant Klebsiella pneumonia
  Prof S Rooijakkers, Prof A Blom
Application Deadline: 10 November 2019

Funding Type

PhD Type

The aim of this project is to characterize complement evasion molecules in the opportunistic bacterium Klebsiella pneumoniae (K. pneumoniae) where carbapenem-resistance grew from 1.6% to 10.4% in 10 years.
  Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease
  Prof M Lowe, Prof V Allan
Applications accepted all year round

Funding Type

PhD Type

Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway.
  Surgical approaches and acute response to small-package implantation of the tympanic membrane
  Prof S Lloyd, Dr M Stone
Application Deadline: 25 October 2019

Funding Type

PhD Type

Most current implantable hearing prostheses require an external package to capture and process sound before transmission to the implant.
  Investigating the role of the mechanosensor channel Piezo1 in human disease
  Dr K Erdmann
Applications accepted all year round

Funding Type

PhD Type

Piezo proteins are ion channels that are gated by mechanical stimuli like stretch or shear stress. In mammalians there are two Piezo isoforms (Piezo1 and Piezo2) with largely different expression pattern.
  Life’s ups and downs: probing the conformational dynamics of DASS transporters, a protein family associated with age-related diseases and lifespan determination (MACMILLANU20DTP)
  Dr F MacMillan, Dr J Angulo
Application Deadline: 25 November 2019

Funding Type

PhD Type

We study the architecture and functional dynamics of membrane proteins, especially many medically relevant membrane transport systems.
  Red blood cells and phagocytosis: how the immune system sorts new cells from old. PhD in Mathematics (GW4 BioMed MRC DTP)
  Dr D Richards
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr David Richards, Department of Mathematics, Living Systems Institute, University of Exeter. Charlie Jeynes, Department of Mathematics, Living Systems Institute, University of Exeter.
  Molecular analysis of neutrophil extracellular traps (NETs) in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots
Applications accepted all year round

Funding Type

PhD Type

Neutrophil extracellular traps (NETs) kill pathogens via the release of chromatin and anti-microbial granule enzymes in an extracellular mesh or “net”.
  Identifying cardiac disease markers using non-lethal ’biopsy’ of cells.
  Research Group: School of Biomedical Sciences
  Dr A.J. Smith
Applications accepted all year round

Funding Type

PhD Type

This project will build on our recent exciting discovery that a novel chemical tool, the polymer styrene maleic acid (SMA), can ‘biopsy’ human vascular cells, extracting proteins from the membrane without killing the cells.
  Transglutaminase 2 (TG2) as a novel cancer biomarker and target for chemotherapy
  Research Group: Biomedical Research Group
  Dr P Coussons, Dr C Pike
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Nanoparticles in drug delivery
  Dr G Stenbeck, Dr U Kishore
Applications accepted all year round

Funding Type

PhD Type

Nanoparticles (NPs) are materials with overall dimensions in the nano scale range (5nm-100nm). Due to their unique physicochemical properties, they have found a wide range of applications and are currently explored as drug and gene delivery vehicles.
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