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We have 8 Other (methylation) PhD Projects, Programmes & Scholarships

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Other (methylation) PhD Projects, Programmes & Scholarships

We have 8 Other (methylation) PhD Projects, Programmes & Scholarships

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more

Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more

Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children. Read more

Integrative genomics prioritisation of drug targets

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Investigating the Immune and Inflammatory Response to Traumatic Injury

We are seeking talented, motivated students with a passion for research in the field of immunology and traumatic injury to join the trauma research team lead by Dr Jon Hazeldine (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/hazeldine-jon.aspx). Read more

MSc By Research: Using hypomethylating agents to prevent respiratory infections in older adults

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
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