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We have 12 Other (mr) PhD Projects, Programmes & Scholarships

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Other (mr) PhD Projects, Programmes & Scholarships

We have 12 Other (mr) PhD Projects, Programmes & Scholarships

NIHR Leeds BRC: Development and application of fast Magnetic Resonance Spectroscopic Imaging methods for metabolic profiling

Altered metabolism is a hallmark of many disease states, including cardiovascular and musculoskeletal conditions. Importantly, metabolic profiles may be patient-specific and may for example indicate susceptibility to treatment or malignancy. Read more

Integrative genomics prioritisation of drug targets

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Understanding the role of adiponectin in kidney disease development at a population level

Reduced circulating adiponectin levels are associated with poor outcome in patients with diabetic kidney disease (DKD) (1). Adiponectin has been shown to be protective against the development of DKD in Type 2 diabetic models (2, 3, 4). Read more

Epilepsy and the ageing brain

Our ability to remember ‘where I put my car keys today’ instead of ‘where I put them yesterday’ depends on a computational process called pattern separation. Read more

Using ultrasound thalamotomy as an opportunity to understand the contributions of the human thalamus to decision making and learning

The contribution of the human thalamic nuclei to decision making are poorly understood and a focus of considerable interest given their routine use as safe targets for functional neurosurgery in tremor and Parkinson's disease. Read more

Prognostic Markers in Bladder Cancer

Bladder cancer is the ninth most common malignant disease in the world (Ferlay et al., 2015). Following removal of diseased tissue, cancer reoccurs in approximately 40% of patients and in 8% it metastasises into other tissues. Read more

PhD Studentship: Safer Scoring: Application of mixed methods evaluation to understand ward strain

We seek an outstanding early career researcher or clinician to be appointed to a 3-year PhD studentship to collaborate on a series of projects using mixed methods to explore aspects of patient safety related to effective management of acute deterioration (acute illness) across whole wards/departments, hospitals and patient pathways. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more
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