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Medical / Clinical Science (transcription) PhD Projects, Programs & Scholarships

We have 25 Medical / Clinical Science (transcription) PhD Projects, Programs & Scholarships

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  Kinase regulation of HOX transcription factors – a potential target in cancer?
  Research Group: Institute of Cancer Therapeutics
  Prof R Morgan, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

The HOX genes are a family of transcription factors that have a number of important functions in cancer, including cell survival and metastasis.
  Deciphering the impact of non-coding mutations in disease
  Dr N Owens
Application Deadline: 2 December 2019

Funding Type

PhD Type

Lead Supervisor. Dr Nick Owens, College of Medicine and Health, University of Exeter. Additional Supervisors. Dr Sarah Flanagan, College of Medicine and Health, University of Exeter.
  Identifying genomic and epigenetic factors in different subtypes of pancreatic cancer
  Prof J Carroll
Application Deadline: 15 November 2019

Funding Type

PhD Type

Despite recent advances in the treatment of pancreatic adenocarcinoma (PDAC), the median survival remains. Epigenetic pathway alterations are an emerging mechanism for PDA progression.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 10 January 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 10 January 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  MRC DiMeN Doctoral Training Partnership: The role of circular RNAs in the development and progression of Parkinson’s disease
  Dr M Jackson, Dr M Santibanez-Koref, Dr G Hudson, Dr O Izuogy
Application Deadline: 6 January 2020

Funding Type

PhD Type

In the UK alone there are currently 145,000 people diagnosed with Parkinson’s disease (PD). In an increasingly aged population, this number is rising, with on average 2 people every hour told that they have PD.
  Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks
  Dr A Antonysunil
Applications accepted all year round

Funding Type

PhD Type

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round

Funding Type

PhD Type

The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
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