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Medical / Clinical Science (clinical trial) PhD Projects, Programs & Scholarships

We have 31 Medical / Clinical Science (clinical trial) PhD Projects, Programs & Scholarships

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  Assessing the generalisability of trial findings using large orthopaedic population studies #NDORMS-2020/5
  Assoc Prof J Cook, Prof X Griffin, Assoc Prof B Ollivere
Application Deadline: 10 January 2020

Funding Type

PhD Type

Randomised trials (RCTs) are widely accepted as the preferred approach to evaluating health care interventions. However, the clinical relevance and generalisability of the findings are often disputed.
  Use of EUROQOL-5D (EQ-5D) in orthopaedic trauma trials #NDORMS-2020/4
  Assoc Prof J Cook, Prof X Griffin
Application Deadline: 10 January 2020

Funding Type

PhD Type

Health related quality of life is commonly measured in clinical research studies including Randomised Controlled Trials (RCTs). Perhaps the most commonly used to do this is the Euroqol-5 dimensions (EQ-5D) questionnaire (1).
  MRC DiMeN Doctoral Training Partnership: MicroRNAs in the fat tissue – Next generation biomarkers for predicting drug-induced cardiometabolic disease
  Dr S Pushpakom, Prof M Bushell, Prof M Pirmohamed
Application Deadline: 6 January 2020

Funding Type

PhD Type

Background. Diabetes, obesity and cardiovascular disease (collectively called cardiometabolic disease) remain a major public health problem worldwide.
  Do the health benefits of exercise depend on medication status in type 2 diabetes?
  Prof M Davies, Dr T Yates
Application Deadline: 28 February 2020

Funding Type

PhD Type

The vast majority of those with type 2 diabetes mellitus (T2DM) are prescribed glucose lowering therapies to help manage their condition, with many taking multiple types of therapies concurrently.
  Flavonoid metabolism and cardiometabolic health
  Prof A Cassidy, Prof J Woodside
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Nutrition and reduction in risk of ill-health is currently centre stage globally, and the recent launch of the EAT-Lancet report showcased that food represents one of the greatest health and environmental challenges of the 21st century and highlighted the urgent need to focus on a high plant food diet.
  Defining disease mechanisms and treatment responses in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) by multi-omics profiling and bioinformatical analysis
  Dr B Bax, Dr Y Jamshidi
Application Deadline: 1 January 2020

Funding Type

PhD Type

Clinical trials require validated endpoint measures to provide an assessment of the success of the study treatment. The selection of trial endpoint measures for rare diseases presents considerable challenges due to low patient numbers, clinical heterogeneity and the absence of appropriate or validated endpoints.
  Augmenting Stroke-Focused Cognitive-Behavioural Therapy (ASCOT) (BroomfieldNU19SF)
  Prof N Broomfield, Dr F Gracey, Prof Valerie Pomeroy
Application Deadline: 31 May 2020

Funding Type

PhD Type

One third of stroke survivors develop Post-Stroke Depression (PSD), one quarter post-stroke anxiety (PSA) yet few effective psychological interventions exist.
  Using the function and structure of the motor unit to predict disease course in amyotrophic lateral sclerosis
  Dr J Alix, Prof C McDermott
Application Deadline: 29 January 2020

Funding Type

PhD Type

Motor neurone disease causes progressive muscle paralysis and remains a fatal condition. One of the challenges faced in clinical practice and research is the heterogeneity of the phenotype.
  PhD in Biostatistics – Methods for Quantifying the Utility of Adaptive Designs
  Prof J Wason, Dr M Grayling
Application Deadline: 24 January 2020

Funding Type

PhD Type

Number of awards. 1. Start date and duration. September 2020, three years. Overview. Clinical trials provide the highest form of evidence about effectiveness of new treatments but are very expensive to conduct.
  Cathepsin Z as a novel potential biomarker for osteoporosis
  Dr D Barraclough, Prof L Ranganath
Applications accepted all year round

Funding Type

PhD Type

Supervisors. Dr. Dong Barraclough, Professor Lakshminarayan Ranganath and Professor Sobhan Vinjamuri.
  Identifying novel treatment options for ovarian carcinosarcoma
  Dr H Barker
Application Deadline: 31 January 2020

Funding Type

PhD Type

Location. The Walter and Eliza Hall Institute of Medical Research, University of Melbourne. Supervisors. Prof C. Scott, Dr H. Barker.
  Moving the tipping point: the decision to anticoagulate patients with atrial fibrillation
  Dr RW Wilkinson, Dr IS Siekmann, Prof G Lip, Prof P Lisboa
Applications accepted all year round

Funding Type

PhD Type

Atrial fibrillation (AF) is a heart condition that causes an irregular and often abnormally fast heart rate, and leads to a high risk of stroke and death.
  Precision Imaging Beacon PhD programme

Funding Type

PhD Type

The Precision Imaging Beacon at the University of Nottingham has a mission to transform medical diagnosis and personalised treatment through world-leading advances in imaging.
  Ocular morbidity associated with Giant Cell Arteritis and Polymyalgia Rheumatica – PhD project (YatesMU19SF)
  Dr M Yates, Prof A MacGregor
Application Deadline: 31 May 2020

Funding Type

PhD Type

Polymyalgia Rheumatica (PMR) often co-exists with GCA. PMR is an inflammatory condition of unknown aetiology causing shoulder and hip girdle pain and stiffness.
  Investigation of the effect of host genetic variants on subgingival microbes and gingival inflammation in gingivitis and periodontitis
  Prof L Nibali
Application Deadline: 26 January 2020

Funding Type

PhD Type

Periodontal Infectogenomics studies how host genetic variants can affect the composition of the subgingival biofilm. The aim of this PhD is to test the effect of specific host genetic variants on periodontal inflammation and microbial growth in gingivitis and periodontitis.
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