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Medical / Clinical Science (antimicrobial) PhD Projects, Programs & Scholarships

We have 21 Medical / Clinical Science (antimicrobial) PhD Projects, Programs & Scholarships

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  MRC DiMeN Doctoral Training Partnership: Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Prof S Baker, Dr T Darton
Application Deadline: 6 January 2020

Funding Type

PhD Type

- Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  Antimicrobial prescribing in hospice and palliative care
  Dr C Parsons, Dr D Gilpin
Applications accepted all year round

Funding Type

PhD Type

Terminally ill patients are at high risk of infections and antimicrobial exposure near the end of life. However, the evidence-base to guide prescribers in the use of antibiotics for the treatment of infections in patients receiving hospice and palliative care is currently lacking.
  Identification and characterisation of barriers to antimicrobial resistance gene transfer
  Prof J Lindsay, Dr G Knight
Application Deadline: 1 January 2020

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a great threat to the future of modern medicine (amr-review.org/Publications).
  GW4 BioMed MRC DTP PhD studentship: Defining the role of efflux in bacterial biofilm formation and antimicrobial resistance to develop new treatments for infection
  Dr B V Jones
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  CRISPR-Cas9 gene drives to eradicate antimicrobial resistance from bacterial communities. PhD in Biosciences (SWBio DTP)
  Dr S van Houte
Application Deadline: 2 December 2019

Funding Type

PhD Type

Lead Supervisor. Dr Stineke van Houte, Department of Biosciences, College of Life and Environmental Sciences, University of Exeter.
  MRC DiMeN Doctoral Training Partnership: Sharpening the blunted neutrophil response to antimicrobial resistant fungal infection
  Dr P Elks, Prof A Condliffe, Dr V See, Dr S Johnston
Application Deadline: 6 January 2020

Funding Type

PhD Type

Life-threatening invasive fungal infection is a major health problem in the immunocompromised, and emerging drug resistance is a major threat to global health.
  Relationship between antibiotic therapy and development of antimicrobial resistance in patients with bronchiectasis
  Dr M Tunney, Prof JS Elborn
Applications accepted all year round

Funding Type

PhD Type

To decrease the risk of acute infective exacerbations or flare-ups of their condition, individuals with bronchiectasis are frequently prescribed long-term oral and inhaled antibiotics.
  (BBSRC DTP) How ecological interactions shape mutation rates to antimicrobial resistance
  Research Group: Ecology and Evolution
  Dr C Knight, Prof A McBain, Dr P Paszek, Dr R Krašovec
Application Deadline: 31 January 2020

Funding Type

PhD Type

The chance that an organism mutates, for instance that a microbe mutates to resist an antibiotic, can depend on that organism’s environment.
  How does a new antimicrobial kill the fungi that invade immunosuppressed patients?
  Prof T Levine
Application Deadline: 24 January 2020

Funding Type

PhD Type

Hard-to-treat fungal infections are a growing problem both UK and worldwide (rates respectively 10,000 and 2M/year; mortality 40% and 25%).
  Finding Achilles Heel: Investigating how to control major bacterial pathogens (WEBBERQ20DART)
  Dr M Webber, Prof J Wain
Application Deadline: 2 December 2019

Funding Type

PhD Type

Bacterial infection remains a major cause of morbidity and mortality with hospital acquired infections still common. The increase in numbers of bacterial which are AMR (antimicrobial resistant) makes prevention of infection more important than ever.
  Clinical application of machine learning algorithms to determine appropriate antibiotic use in children with Gram-negative bacteria infections
  Dr Y Hsia, Prof C Hughes
Application Deadline: 31 January 2020

Funding Type

PhD Type

Digital health is a growing and productive field in recent years. The application of machine learning (ML) techniques in electronic healthcare databases has been successfully used for clinical diagnosis, outcome prediction, and disease progression.
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  A network approach to understanding the spread of antibiotic resistance. PhD in Biosciences (GW4 BioMed MRC DTP)
  Prof A Buckling
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Professor Angus Buckling, Department of Biosciences, College of Life and Environmental Sciences, University of Exeter.
  Determining the microbiome of the homes of people with chronic respiratory diseases
  Dr D Gilpin, Dr D Downey
Applications accepted all year round

Funding Type

PhD Type

In recent years, our understanding of the microbial world in and around us has radically changed. The idea that we live with a complex and diverse community of microbes, has moved us away from a “hygiene hypothesis”, where having less bacteria was, to put it simply, better.
  Using Genomics and Peptidomics to Identify and Optimize Antibiofilm Peptides against Multi-drug Resistant Bacteria
  Dr K Hilpert, Prof D Baines
Application Deadline: 1 January 2020

Funding Type

PhD Type

The UK’s Chief Medical Officer raised the alarm in 2013, saying antibiotic resistant is a “ticking time bomb” comparable to climate change and terrorism.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Elucidating the emergence of multi-drug resistant Enterococcus faecium
  Prof W Van Schaik, Dr A McNally
Applications accepted all year round

Funding Type

PhD Type

The Gram-positive bacterium Enterococcus faecium is a commensal of the intestinal tract of humans and animals. However, over the last two decades a clone of E.
  Cracking down bacterial infection in bone by new photo-responsive nanoparticles
  Dr K Yeung
Applications accepted all year round

Funding Type

PhD Type

Bio-metals have been extensively used in orthopaedic implantations. However, bacterial infection and unsatisfactory integration at the bone-implant interface remain major post-operative complications.
  Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A O'Neill
Applications accepted all year round

Funding Type

PhD Type

The World Health Organization (WHO) has declared antimicrobial drug resistance one of the greatest problems currently facing human health, and the situation is especially grave in the case of infections caused by bacterial pathogens.
  Alpha-defensin haplotypes and IgA nephropathy risk
  Prof J A L Armour, Prof O Hanotte
Applications accepted all year round

Funding Type

PhD Type

The human alpha-defensin genes DEFA1 and DEFA3 encode short antimicrobial peptides that are important components of the innate immune system, and are subject to copy number variation (CNV) with individuals having between 3 and 18 copies.
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