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Medical / Clinical Science (flow cytometry) PhD Projects, Programs & Scholarships

We have 51 Medical / Clinical Science (flow cytometry) PhD Projects, Programs & Scholarships

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  Single-molecule fluorescence-activated cell sorting (smFACS): sorting cells molecule by molecule
  Research Group: Molecular and Nanoscale Phsyics
  Dr A Ponjavic
Application Deadline: 28 February 2020

Funding Type

PhD Type

This project will develop a novel microfluidic device that can characterise and sort cells, with unprecedented (single-molecule) sensitivity.
  Immune phenotyping of refractory rheumatoid arthritis disease
  Prof Maya Buch, Dr S Viatte
Applications accepted all year round

Funding Type

PhD Type

Treatment of rheumatoid arthritis (RA) has been transformed with the introduction of targeted therapies twenty years ago (comprising biologic disease modifying anti-rheumatic drugs, bDMARDS; and the more recent small molecule JAK inhibitors).
  Analysing immune responses to metastatic ovarian tumours to identify therapeutic targets
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Investigating how ovarian tumours avoid immune responses in cancer patients
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Therapeutic targeting of chemokines in inflammation
  Prof S Bhattacharya
Application Deadline: 24 July 2020

Funding Type

PhD Type

Inflammation, driven by leucocytes, adversely affects organ function in diseases such as myocarditis, myocardial infarction, acute lung injury, sepsis and pancreatitis,.
  Impact of Inflammatory Signals on the Regenerative, Anti-inflammatory and Immunomodulatory Potential of Human Mesenchymal Stem Cells and their Secretome
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Adult multipotent stem cells can be easily isolated from a variety of adult human tissues and organs including bone marrow and adipose tissue.
  Can neutrophil microvesicles influence the phenotype of monocytes - linking systemic inflammation with heart disease
  Dr V Ridger, Prof E Kiss-Toth
Applications accepted all year round

Funding Type

PhD Type

Cardiovascular disease (CVD) remains the leading cause of death worldwide. Atherosclerosis, the build up of fibro-fatty plaques in the wall of arteries, is the underlying cause of the heart attack and stroke.
  Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
  Dr S Eyre, Mr P Martin, Dr AM Morris
Applications accepted all year round

Funding Type

PhD Type

Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect.
  The molecular mechanisms of thrombosis and haemostasis
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

A healthy cardiovascular system relies on the cells lining the blood vessels (endothelial cells) and heart cells (cardiomyocytes) to function normally.
  The potential of elevating Epac2 to modulate glial activation and promote motor neuron regeneration in Amyotrophic Lateral Sclerosis
  Dr W Huang, Dr G S Bewick
Application Deadline: 13 March 2020

Funding Type

PhD Type

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterised by the selective degeneration and death of motor neurons.
  Transglutaminase 2 (TG2) as a novel cancer biomarker and target for chemotherapy
  Research Group: Biomedical Research Group
  Dr P Coussons, Dr C Pike
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  PhD position/Graduate Research Assistantship in the area of Allergy, Asthma and Immunology
  Dr A Mishra
Applications accepted all year round

Funding Type

PhD Type

The Laboratory of Lung Inflammation, Department of Pathobiology, College of Veterinary Medicine at Auburn University have opening for highly motivated PhD candidate/ Graduate Research Assistant to work on NIH-funded research project in the area of Allergy, Asthma and Immunology.
  The development of the respiratory immune system in early life
  Dr R Thwaites
Application Deadline: 13 April 2020

Funding Type

PhD Type

We seek a highly motivated PhD student to study mucosal immunology of the infant airway and the responses to viral infections. Immediately after birth, the respiratory epithelium is coated with allergens, dust, pollutants and is colonised by commensal bacteria.
  ExomiR resetting of the energy profile in Hepatocellular Cancer (HCC) via the mitochondrial proteome
  Prof N Heaton, Dr S E Khorsandi
Application Deadline: 30 April 2020

Funding Type

PhD Type

Project description. The issue/problem. Hepatocellular cancer (HCC) is a primary liver cancer and one of the commonest cancers in the world.
  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  Therapy-induced senescence and stemness in ovarian cancer
  Prof R. Pearson, Dr K Chan
Applications accepted all year round

Funding Type

PhD Type

Cellular senescence is a stress response characterized by a robust cell cycle arrest and is a brake for malignant transformation.
  Defining how skin fibroblast lineage identity and specificity is maintained ex vivo
  Dr E Rognoni, Dr J Connelly
Application Deadline: 6 March 2020

Funding Type

PhD Type

This is an exciting opportunity for a PhD studentship within the world-renowned William Harvey Research Institute at Barts and The London Medical School and Dentistry (SMD) at Queen Mary University of London (QMUL).
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  Determining how immune responses are regulated at mucosal surfaces
  Prof M Travis, Prof D Thornton
Applications accepted all year round

Funding Type

PhD Type

The immune system must be primed to quickly respond to infection, but must also be tightly regulated so it ignores harmless substances and our own tissues.
  Predicting treatment response in juvenile idiopathic arthritis using a single cell genomics based approach
  Prof W Thomson, Dr S Smith, Mr P Martin, Prof A Morris
Applications accepted all year round

Funding Type

PhD Type

Background. Juvenile idiopathic arthritis (JIA) is a group of chronic arthropathies of unknown cause which can result in long-term disability and poor quality of life for children and can continue well into adult life.
  The role of the microenvironment in regulating breast cancer metastatic colonisation
  Dr R Clarke, Dr Ciara O'Brien, Dr R Eyre
Applications accepted all year round

Funding Type

PhD Type

The metastatic spread of breast cancer cells and their colonisation of important organs is the cause of death in 95% of breast cancer.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Precision Medicine DTP - Identifying Pathogenic B cells in Rheumatoid Arthritis
  Research Group: Centre for Inflammation Research
  Dr M Gray, Prof C Goodyear, Dr G Cowan
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Rheumatoid Arthritis (RA) is the commonest, most destructive, autoimmune inflammatory arthritis, causing chronic pain, fatigue, depression and disability.
  Precision Medicine DTP - Illuminating roles of Wnt/b-Catenin signalling in nonalcoholic fatty liver disease (NAFLD)
  Research Group: MRC Centre for Regenerative Medicine
  Dr K Kaji, Dr S Tomlinson, Prof J Fallowfield
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Non-Alcoholic Fatty Liver Disease (NAFLD) caused by a high fat diet (HFD) is a growing major public health problem world-wide.
  Enhancing Oncolytic Virus-induced Immunotherapy using Eicosapentaenoic Acid (EPA)
  Dr F Errington-Mais, Dr MA Volpato
Applications accepted all year round

Funding Type

PhD Type

Breast cancer is the most commonly diagnosed cancer in women with triple-negative breast cancer (TNBC) having the worst prognosis, highest death rate and lowest overall survival.
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  Molecular modelling and analysis of plasma cell cancers
  Dr R Tooze, Dr G Doody, Dr R Owen
Application Deadline: 10 March 2020

Funding Type

PhD Type

Plasma cell neoplasms, including multiple myeloma, are cancers of the immune system that remain largely incurable despite major advances in therapy.
  Personalised anti-viral immunotherapies for hepatitis B and C virus-associated hepatocellular carcinoma
  Dr A Samson, Dr S Griffin
Application Deadline: 28 February 2020

Funding Type

PhD Type

Hepatocellular carcinoma (HCC) is a cancer of hepatocytes commonly caused by hepatitis B and C virus (HBV/HCV) infections. Only 12% of HCC patients survive for five-years, due to late diagnosis and inadequate non-personalised therapies.
  Joint PhD with University of Manchester: Identifying the mechanisms of sub-clinical corneal inflammation during contact lens wear
  Dr L Downie, Dr C Maldonado-Codina
Application Deadline: 13 March 2020

Funding Type

PhD Type

Have you ever wondered what happens to the surface of the eye when you apply a contact lens? Some people suffer from red and painful eyes with their contact lenses and many wearers suffer from discomfort at the end of each lens-wear day.
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