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Medical / Clinical Science (information studies) PhD Projects, Programs & Scholarships

We have 154 Medical / Clinical Science (information studies) PhD Projects, Programs & Scholarships

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Showing 31 to 60 of 154
  Functional coronary artery disease genetics - Defining the function of new causal atherosclerosis genes from CAD GWAS loci using in vitro and in vivo models
  Dr G Douglas, Prof K Channon
Application Deadline: 10 January 2020

Funding Type

PhD Type

Despite significant advancements in its treatment coronary artery disease is the leading cause of death in both the UK and world wide, accounting for over 66,000 deaths in the UK each year.
  Genetic Architecture of Inherited Cardiomyopathy
  Prof M Farrall, Dr AG Goel, Prof H Watkins
Application Deadline: 10 January 2020

Funding Type

PhD Type

Studying genetic variation in cardiomyopathy and coronary artery disease across the entire allele frequency spectrum in order to identify causative genes and susceptibility loci.
  Human liver fat metabolism and metabolic disease: Understanding the underlying causes and mechanistic basis for intrahepatic fat storage to identify ways of preventing and treating fatty liver disease.
  Prof L Hodson, Dr K Pinnick, Dr S Parry
Application Deadline: 10 January 2020

Funding Type

PhD Type

Understanding the underlying causes and mechanistic basis for intrahepatic fat storage to identify ways of preventing and treating fatty liver disease.
  Myocardial biology with a specific focus on the mechanisms underlying cardiac fibrosis and atrial fibrillation
  Dr S Reilly, Prof C Redwood, Assoc Prof M Lei
Application Deadline: 10 January 2020

Funding Type

PhD Type

Cardiac fibrosis is a hallmark histological feature of structural changes in the myocardium associated with virtually all cardiac diseases (e.g., heart failure, hypertension, atrial fibrillation and myocarditis).
  The Genomics of Hereditary Prostate Cancer
  Prof R Bristow
Application Deadline: 3 January 2020

Funding Type

PhD Type

This 4 year PhD studentship offered in Professor Rob Bristow’s research group is based at the Cancer Research UK Manchester Institute, Manchester Cancer Research Centre, Oglesby Cancer Research Building, Manchester.
  MRC DiMeN Doctoral Training Partnership: Using wearable technology to identify activity and sleep patterns in inpatients with delirium and Parkinson’s disease
  Dr R Lawson, Dr S Del Din, Dr A Yarnall, Dr J Shi
Application Deadline: 6 January 2020

Funding Type

PhD Type

We are offering an enthusiastic and motivated PhD student the exciting opportunity to join our international renowned team.
  Using Genomics and Peptidomics to Identify and Optimize Antibiofilm Peptides against Multi-drug Resistant Bacteria
  Dr K Hilpert, Prof D Baines
Application Deadline: 1 January 2020

Funding Type

PhD Type

The UK’s Chief Medical Officer raised the alarm in 2013, saying antibiotic resistant is a “ticking time bomb” comparable to climate change and terrorism.
  Precision Medicine DTP - Understanding the neurobiological basis of co-morbid chronic pain and depression by integrating genomics, peripheral biomarkers and neuroimaging data
  Research Group: Centre for Clinical Brain Sciences
  Dr H Whalley, Prof M Fallon, Dr D Smith, Dr T-K Clarke
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic pain is a major public health problem affecting one fifth of the general population(1). Major depressive disorder (MDD) is also a major health concern and is now the leading cause of disability worldwide(2).
  Precision Medicine DTP – Using Omics to Understand the Genes and Pathways Underlying Alcohol Use Disorder
  Research Group: Centre of Genomic and Experimental Medicine
  Dr K Evans, Dr T-K Clarke, Dr S Glerup
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Alcohol use disorder (AUD) is a chronic relapsing brain disease characterised by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional state when not using alcohol.
  Development of new anti-obese strategies by conversion of white fat to brown fat
  Prof A Xu
Applications accepted all year round

Funding Type

PhD Type

In contrast to white adipose tissue (WAT) that stores energy, brown adipose tissue (BAT) is specialized for energy dissipation and considered as a potential weapon to combat obesity by uncoupling mitochondrial respiratory chain and ATP synthesis.
  MRC DiMeN Doctoral Training Partnership: Machine learning approaches for the analysis of circulating tumour DNA
  Dr A Auer-Fowler, Dr A Jorgensen, Dr J Cook
Application Deadline: 6 January 2020

Funding Type

PhD Type

Tumour cells arise from genetic variants (usually mutations) in cells, which lead to unrestrained cell division.
  Understanding the role of the pericardial adipose and locally synthesized steroids in the heart
  Prof LM Delbridge, Dr JR Bell
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for a PhD student to join the Cardiac Phenomics laboratory at the University of Melbourne. Our University is ranked 9th in the world for pre-clinical biomedical research (Times Higher Education).
  Can orally delivered gas nanobubbles relieve joint hypoxia #NDORMS 2020/10
  Prof E Stride, Prof D Richards, Dr L Coates, Prof P Hulley
Application Deadline: 10 January 2020

Funding Type

PhD Type

Joint hypoxia is a feature of many rheumatological conditions and results in upregulation of HIF (hypoxia-inducible factors). HIFs are thought to mediate a number of maladaptive features of joint disease, but to date attempts to develop small molecule inhibitors of HIF have not been successful.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  Analytic methods for detecting and making sense of somatic genomic rearrangements
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Computational simulation of tumour formation and progression
  Dr D. Goode
Applications accepted all year round

Funding Type

PhD Type

Tumours comprise a complex mix of related but distinct cellular subpopulations that both compete and complement one another. These dynamics strongly influence how and when a tumour forms as well as its response to therapy, however there are hard to observe directly.
  Fishing for metabolic clues: Role of the Hippo/Yap pathway in reprogramming metabolism in liver cancer
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

The Hippo/Yap pathway is an evolutionarily conserved cascade that plays a fundamental role in governing organ size control, stem cell homeostasis and cancer.
  Genomic determinants of long-term survival in ovarian cancer
  Research Group: Cancer Genetics & Genomics Laboratory
  Prof D. Bowtell, Dr D Garsed
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer is an aggressive disease in which only ~30% of women survive 5 years or more. Despite a poor prognosis, a subset of patients are highly responsive to chemotherapy, and some become long-term survivors (>10 years survival).
  Investigating the requirements of pro-inflammatory signaling in skin and head & neck Squamous Cell Carcinomas
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Squamous cell carcinomas (SCC) are amongst the most common cancer types afflicting man. SCCs most frequently arise from stratified squamous epithelia such as the epidermis or the mucosae of the head and neck.
  Metabolic Reprogramming in Liver Cancer: delineating the role of reactive oxygen species (ROS) in tumour development
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in cancer metabolism and obesity-associated liver cancer.
  mRNA translation reprogramming and metabolic re-wiring in response to ribosome-targeted therapies
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Increased synthesis and activity of ribosomes are associated with oncogenesis downstream of the major oncogenes including MYC, RAS and PI3K.
  Role of the tumour microenvironment in gastric cancer
  Dr A. Boussioutas, Dr R. Busuttil
Applications accepted all year round

Funding Type

PhD Type

Gastric cancer (GC) is the fourth most common cancer globally and 7th in incidence in Australia. It has a poor survival rate which can be attributed to the advanced stage at diagnosis in most patients.
  Targeting IDH mutations in acute myeloid leukaemia
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

Acute Myeloid Leukaemia (AML) is an aggressive disease with poor prognosis and development of novel treatment options is urgently needed.
  The role of oesophageal submucosal glands in epithelial homeostasis and the development of Barrett’s oesophagus
  Research Group: Cancer Biology & Surgical Oncology Laboratory
  Prof W. Phillips, Dr N. Clemons
Applications accepted all year round

Funding Type

PhD Type

Barrett’s oesophagus, the premalignant precursor of oesophageal adenocarcinoma, is a metaplastic condition where the normal stratified squamous epithelium that lines the oesophagus is replaced by an intestinal-like columnar epithelium.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  Therapy-induced senescence and stemness in ovarian cancer
  Prof R. Pearson, Dr K Chan
Applications accepted all year round

Funding Type

PhD Type

Cellular senescence is a stress response characterized by a robust cell cycle arrest and is a brake for malignant transformation.
  Transcriptional heterogeneity and resistance to therapy in prostate cancer
  Dr D. Goode
Applications accepted all year round

Funding Type

PhD Type

Androgen deprivation therapy (ADT) is a standard treatment for prostate cancer that works well in many cases but rapidly fails in others.
  Unravelling the oncogenic activities of serum- and glucocorticoid-regulated kinase 1 (SGK1)
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

The phosphoinositide 3-kinase (PI3K) pathway is a master regulator of numerous cellular phenotypes associated with cancer including cell survival, proliferation, growth, altered metabolism and malignant transformation.
  Using T cells to eradicate cancer
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in immuno-oncology and the development of novel immunotherapeutic approaches for the treatment of cancer.
  Micro-environmental Interactions And Non-Coding RNAs In The Biology Of B Cell Leukemia
  Prof M Mráz
Application Deadline: 20 February 2020

Funding Type

PhD Type

We are looking for motivated PhD students for a project funded by the prestigious ERC (European Research Council) Grant (laboratory of Assoc.
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