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Medical / Clinical Science (pathogens) PhD Projects, Programs & Scholarships

We have 27 Medical / Clinical Science (pathogens) PhD Projects, Programs & Scholarships

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  Development of a single NGS pipeline using a novel universal virus enrichment panel for the detection and typing of viral pathogens.
  Prof L Scobie, Dr R Gunson
Applications accepted all year round

Funding Type

PhD Type

Project reference number. SHLS19001. Current routine virology diagnostics rely upon serological methods and novel molecular methods such as real time PCR.
  Subversion of small GTPases for host exploitation by intracellular bacterial pathogens
  Research Group: Centre for Experimental Medicine
  Dr G Schroeder, Prof M Valvano, Dr B Collins
Application Deadline: 20 January 2020

Funding Type

PhD Type

The rise of antibiotic resistance as well as growing populations with compromised health and immunity, make bacterial pathogens one of the most important threats to human health and global development.
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Dissecting how the human pathogen Klebsiella pneumoniae rewires macrophages to promote infection
  Research Group: Centre for Experimental Medicine
  Prof J Bengoechea, Prof P Moynagh
Application Deadline: 20 January 2020

Funding Type

PhD Type

Macrophages represent play a critical role in host defence against pathogens. Therefore, pathogens should overcome macrophages’ antimicrobial programme to promote infection.
  Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.
  Dr M Welch
Applications accepted all year round

Funding Type

PhD Type

We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria.
  Evolution of Influenza Viruses - prediction of possible future antigenic variants
  Prof D Smith
Application Deadline: 2 January 2020

Funding Type

PhD Type

Evolution of Influenza Viruses. Centre for Pathogen Evolution. Department of Zoology. University of Cambridge. Project summary. Our research focus is to design and develop analytical, computational, and mathematical methods to understand the fundamental processes that govern the evolution of influenza viruses.
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  Understanding the impact of co-infection on lung immune responses and allergy
  Prof R May, Dr C Pashley, Dr D Cunningham
Application Deadline: 17 January 2020

Funding Type

PhD Type

Alveolar macrophages are white blood cells that provide an essential first line of defence in the lung. They hunt, engulf and destroy invading pathogens.
  Using live-cell imaging of the immune response to investigate host-pathogen interactions during infection.
  Prof R May
Application Deadline: 10 January 2020

Funding Type

PhD Type

My group is interested in the molecular and cellular mechanisms that occur during host-pathogen interactions.
  The MRC-University of Glasgow Centre for Virus Research (CVR) PhD Funded Programme

Funding Type

PhD Type

Viral diseases kill many millions of people each year and are a significant global challenge to human health and prosperity. We have created a specialised MRC programme to train the next generation of scientists and leaders in virology research.
  Understanding Factors That Regulate Respiratory Microbiota
  Dr L Sadofsky, Dr S Hart
Application Deadline: 29 January 2020

Funding Type

PhD Type

This PhD project is based in Hull York Medical School. The upper respiratory tract is colonized by an extensive and diverse normal microbiota, many constituents of which are potential pathogens.
  Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A O'Neill
Applications accepted all year round

Funding Type

PhD Type

The World Health Organization (WHO) has declared antimicrobial drug resistance one of the greatest problems currently facing human health, and the situation is especially grave in the case of infections caused by bacterial pathogens.
  Iron Biology
  Prof H Drakesmith, Dr O Bannard
Application Deadline: 10 January 2020

Funding Type

PhD Type

We study how iron and anaemia influence immunity and infectious diseases. Our research inspires therapies that control iron physiology to improve immunity, combat infections and treat disorders of iron metabolism.
  Iron Biology
  Prof H Drakesmith, Dr O Bannard
Application Deadline: 10 January 2020

Funding Type

PhD Type

We study how iron and anaemia influence immunity and infectious diseases. Our research inspires therapies that control iron physiology to improve immunity, combat infections and treat disorders of iron metabolism.
  MRC DiMeN Doctoral Training Partnership: A New Front in Microbial Warfare—Delivery of Antifungal Effectors by the Type VI Secretion System
  Prof J Quinn, Dr C Stewart
Application Deadline: 6 January 2020

Funding Type

PhD Type

The type VI secretion system (T6SS) is widely used by bacteria to fire diverse effector proteins directly into neighbouring target cells.
  The role of SORL1 in B cell antigen trafficking
  Research Group: Centre for Experimental Medicine
  Dr D Malinova, Dr A Kissenpfennig
Application Deadline: 20 January 2020

Funding Type

PhD Type

B cells are a crucial element of adaptive immunity by producing antibodies to neutralise invading pathogens. For an effective antibody response, a B cell must interact with and internalise (endocytose) antigens through its surface B cell receptor.
  Modelling lung deposition of inhaled particles in cystic fibrosis
  Prof O Jensen, Dr A Horsley, Dr C Whitfield
Application Deadline: 9 September 2020

Funding Type

PhD Type

Cystic fibrosis (CF) is a genetic disorder that affects the production and clearance of mucus from various organs in the body. In the lungs this causes blockage and thickening of airways, leading to lung damage and early death from respiratory failure.
  Do Altered host-microbial interactions promote oral inflammation during ageing?
  Dr J Konkel, Prof A McBain
Applications accepted all year round

Funding Type

PhD Type

As we age, the systems of our bodies become less able to function; rendering people increasingly infirm. Ageing affects our immune system, impeding our ability to both fight infection and maintain tolerance.
  15 three-year PhD studentships - Marie- Sklodowska-Curie (MSCA) Innovative Training Network “BactiVax” within the Horizon 2020 Programme of the European Commission

Funding Type

PhD Type

Applications are invited for 15 three-year PhD studentships to be funded by the Marie- Skłodowska-Curie (MSCA) Innovative Training Network “BactiVax” within the Horizon 2020 Programme of the European Commission (Grant Agreement 860325).
  EASTBIO A synthetic biology approach to design ‘intelligent’ organoids for the study of host-microbe interactions
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr E Cachat, Dr L Boulter
Application Deadline: 5 January 2020

Funding Type

PhD Type

Organoids are self-organised, 3D structures generated in vitro from adult or pluripotent stem cells, that exhibit similar functionality as their tissue of origin.
  Fully Funded PhD - Bacterial sepsis: Assessing novel molecular methods for rapid diagnosis, improved patient outcomes and reduced antimicrobial resistance
  Dr T Forde, Dr P Everest, Dr K Brunker, Dr K Oravkova
Application Deadline: 13 January 2020

Funding Type

PhD Type

We are seeking applicants for a fully-funded 4-year PhD position at the University of Glasgow. The position is open to UK, EU, and international applicants.
  Molecular analysis of neutrophil extracellular traps (NETs) in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots
Applications accepted all year round

Funding Type

PhD Type

Neutrophil extracellular traps (NETs) kill pathogens via the release of chromatin and anti-microbial granule enzymes in an extracellular mesh or “net”.
  Development and Maturation of B cell Mediated Immune Responses
  Dr O Bannard
Application Deadline: 10 January 2020

Funding Type

PhD Type

We study the cellular interactions and molecular events that lead to the development of high affinity and protective antibodies during humoral immune responses.
  MRC DiMeN Doctoral Training Partnership: Sharpening the blunted neutrophil response to antimicrobial resistant fungal infection
  Dr P Elks, Prof A Condliffe, Dr V See, Dr S Johnston
Application Deadline: 6 January 2020

Funding Type

PhD Type

Life-threatening invasive fungal infection is a major health problem in the immunocompromised, and emerging drug resistance is a major threat to global health.
  MRC DiMeN Doctoral Training Partnership: Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Prof S Baker, Dr T Darton
Application Deadline: 6 January 2020

Funding Type

PhD Type

- Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  Biochemical mechanism controlling bacterial evasion of human inflammasome
  Dr D Boucher, Dr M van der Woude
Application Deadline: 5 January 2020

Funding Type

PhD Type

Your body is constantly targeted by pathogens like Salmonella, a food-borne. pathogen. Immune cells recognize and protect your body against infections.
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