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Medical / Clinical Science (php) PhD Projects, Programs & Scholarships

We have 23 Medical / Clinical Science (php) PhD Projects, Programs & Scholarships

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  A 3D in vitro model of wound healing incorporating skin, nerves and immune cells
  Dr A M Rajnicek, Prof H M Wilson
Applications accepted all year round

Funding Type

PhD Type

Diabetes, paralysis, being bed ridden and other conditions can result in chronic wounds that fail to heal, with significant personal consequences for patients and an annual cost of £4.5-5.1 billion annually (Guest et al., 2015) to the National Health Service.
  Development of ex vivo tissue culture models for developing next-generation biomaterial scaffolds for acellular regenerative medicine.
  Prof I Gibson, Prof N Vargesson
Applications accepted all year round

Funding Type

PhD Type

Bone repair and regeneration can be influenced by various guidance cues, including pharmacological cues, hypoxia environment and chemical cues released from scaffolds [1-3].
  Getting to grips with severe asthma - a whole population approach using routinely acquired data.
  Prof S Turner, Dr D Miller
Applications accepted all year round

Funding Type

PhD Type

There are 500,000 people in Scotland who have asthma. Asthma symptoms range from mild through moderate to severe. Severe asthma is not common but since it is associated with morbidity and mortality, severe asthma is a considerable burden to patients, society and the NHS.
  Non-invasive Mapping of Oxygen Extraction Fraction in Patients with Breast Cancer: Development of Novel Multi-Parametric Relaxometry Magnetic Resonance Imaging (MRI) Methods
  Dr J He, Dr Y Masannat, Prof D Lurie
Applications accepted all year round

Funding Type

PhD Type

This project aims to translate, optimise and extend quantitative oxygen extraction fraction mapping based on oxygen enriched air inspiration and magnetic resonance (MR) relaxometric imaging for human application.
  Understanding the health behaviour behind GP help-seeking with potential cancer symptoms.
  Prof P Murchie, Dr D Powell, Dr R Vieira
Applications accepted all year round

Funding Type

PhD Type

1. Background to the project.
  Flavonoid metabolism and cardiometabolic health
  Prof A Cassidy, Prof J Woodside
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Nutrition and reduction in risk of ill-health is currently centre stage globally, and the recent launch of the EAT-Lancet report showcased that food represents one of the greatest health and environmental challenges of the 21st century and highlighted the urgent need to focus on a high plant food diet.
  Genome scale evolution of biofilm contained Klebsiella pneumoniae in response to sub-lethal antibacterial stress exposure - development of novel biomarkers for near-patient testing
  Prof S Fanning, Prof B Gilmore
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Klebsiella pneumoniae is an opportunistic pathogenic bacterium found in several niches, being often encountered in a biofilm.
  Investigating how the levels of queuine, a novel micronutrient, are associated with human ageing and brain health
  Dr B Green, Prof G Hardiman
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Queuine is the only micronutrient that directly affects translation efficiency and accuracy in eukaryotes, with roles in metabolism and healthy-aging of the brain.
  Mast cell dysregulation? Understanding the development of mastocytosis
  Dr C Graham, Dr B Graham, Prof C Creevey
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Mastocytosis is a myeloproliferative disease characterised by the accumulation of neoplastic mast cells in one or several organs that can result in organ failure.
  MicroRNAs in the Pathogenesis Adverse Cardiomyocyte and Endothelial Cell Remodelling in Insulin Resistance
  Dr Q Su, Dr D Grieve
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Lipogenic diets-induced diabetes increases risk of cardiac stress and vascular dysfunction. Recent studies have established the pivotal role of non-coding microRNAs in the pathogenesis of cardiovascular disease (CVD).
  Precision Medicine DTP - An integrated computational-experimental approach to identify and optimise combination drug therapy for non-alcoholic fatty liver disease (NAFLD)
  Research Group: Centre for Inflammation Research
  Prof J Fallowfield, Dr F Menolascina, Prof J Plevris
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Non-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease (CLD), affecting 1 in 4 people worldwide.
  Precision Medicine DTP - Analysing and recommending personalised care pathways for multimorbid patients with the use of artificial intelligence techniques
  Research Group: Centre for Medical Informatics
  Dr A Manataki, Dr D Wake, Dr S Cunningham
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Multimorbidity is one of the biggest challenges that health services are facing in the UK and worldwide. Care for people living with multiple conditions accounts for over half of the costs of primary and secondary care in the UK, and the number of these patients is rising.
  Precision Medicine DTP - Developing data science approaches to improve paediatric critical care patient flows and its related health economics benefits in Scotland
  Research Group: Centre for Medical Informatics
  Dr T Lo, Dr A Manataki, Dr L Moss, Dr A Neilson
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Paediatric critical care (PCC) is a highly valued specialist service that saves infants and children’s life. Over the past decade, the demand of PCC beds exceeds the expected population growth in the UK.
  Precision Medicine DTP - How do IFITM proteins regulate the Interferon Related DNA-damage Resistance Signature (IRDS) and clinical outcomes in cancers of high unmet clinical need?
  Dr R Sloan, Prof K Ball, Dr S Wilson
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Interferon Induced Transmembrane proteins (IFITMs) are a family of innate immune membrane proteins that can inhibit viral infection at cell entry (e.g.
  Precision Medicine DTP - Identifying Pathogenic B cells in Rheumatoid Arthritis
  Research Group: Centre for Inflammation Research
  Dr M Gray, Prof C Goodyear, Dr G Cowan
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Rheumatoid Arthritis (RA) is the commonest, most destructive, autoimmune inflammatory arthritis, causing chronic pain, fatigue, depression and disability.
  Precision Medicine DTP - Illuminating roles of Wnt/b-Catenin signalling in nonalcoholic fatty liver disease (NAFLD)
  Research Group: MRC Centre for Regenerative Medicine
  Dr K Kaji, Dr S Tomlinson, Prof J Fallowfield
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Non-Alcoholic Fatty Liver Disease (NAFLD) caused by a high fat diet (HFD) is a growing major public health problem world-wide.
  Precision Medicine DTP – Integration of single-cell RNA sequencing data from human and murine kidney disease to identify novel therapeutic targets
  Research Group: Centre for Cardiovascular Science
  Dr BC Conway, Dr T Chandra, Dr D Ferenbach
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease and for end-stage kidney disease (ESRD), at which point patients require dialysis or transplantation.
  Precision Medicine DTP - Omics Prediction of Incident Disease
  Research Group: Centre of Genomic and Experimental Medicine
  Dr R Marioni, Dr C Hayward, Dr C Vallejos
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Disease prediction years prior to onset is a major goal for biomedical research. This may be possible through the development of cutting edge statistical and machine learning tools and their application to millions of biological data points from thousands of individuals.
  Precision Medicine DTP - Taming the Hippo in mesothelioma through proteogenomics
  Research Group: Centre for Inflammation Research
  Dr C G Hansen, Prof J Lehtio
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Pleural Mesothelioma is an asbestos-related cancer, which originates in the pleural lining of the lung and is characterized by a diverse phenotype.
  Precision Medicine DTP - Understanding the neurobiological basis of co-morbid chronic pain and depression by integrating genomics, peripheral biomarkers and neuroimaging data
  Research Group: Centre for Clinical Brain Sciences
  Dr H Whalley, Prof M Fallon, Dr D Smith, Dr T-K Clarke
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic pain is a major public health problem affecting one fifth of the general population(1). Major depressive disorder (MDD) is also a major health concern and is now the leading cause of disability worldwide(2).
  Precision Medicine DTP – Using Omics to Understand the Genes and Pathways Underlying Alcohol Use Disorder
  Research Group: Centre of Genomic and Experimental Medicine
  Dr K Evans, Dr T-K Clarke, Dr S Glerup
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Alcohol use disorder (AUD) is a chronic relapsing brain disease characterised by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional state when not using alcohol.
  Control and inhibition of virus replication
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A.K Tuplin
Applications accepted all year round

Funding Type

PhD Type


The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specificaly Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.
  Clinical application of machine learning algorithms to determine appropriate antibiotic use in children with Gram-negative bacteria infections
  Dr Y Hsia, Prof C Hughes
Application Deadline: 31 January 2020

Funding Type

PhD Type

Digital health is a growing and productive field in recent years. The application of machine learning (ML) techniques in electronic healthcare databases has been successfully used for clinical diagnosis, outcome prediction, and disease progression.
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