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Medical Research Council (Cambridge) PhD Projects, Programs & Scholarships

We have 52 Medical Research Council (Cambridge) PhD Projects, Programs & Scholarships

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  Mechanisms of molecular machines
  Dr L Passmore
Application Deadline: 3 December 2019

Funding Type

PhD Type

Gene expression is tightly controlled to allow rapid responses to cellular stimuli. It is regulated through transcription, translation and mRNA stability.
  Mechanisms of regulation of the phosphoinositide 3-kinase family of enzymes
  Dr R Williams
Application Deadline: 3 December 2019

Funding Type

PhD Type

Our research programme aims at establishing mechanisms of regulation of an ancient family of giant kinases involved in cellular homeostasis.
  Mechanisms of selective cell vulnerability to protein assembly propagation in neurodegenerative disease
  Dr B Falcon
Application Deadline: 3 December 2019

Funding Type

PhD Type

The assembly of a small number of proteins into amyloid structures within neurons and, in some cases, glia underlies neurodegenerative disease.
  Membrane protein biogenesis and quality control
  Dr R Hegde
Application Deadline: 3 December 2019

Funding Type

PhD Type

Approximately 20-25% of genes in humans encode integral membrane proteins that must be selectively targeted to and inserted into the endoplasmic reticulum (ER) membrane.
  Neural circuit basis of sexually dimorphic and learned behaviours in Drosophila
  Dr G Jefferis
Application Deadline: 3 December 2019

Funding Type

PhD Type

We study how sensory information is transformed into behaviour in the fly brain. We mostly use the olfactory system, because olfaction is a relatively shallow sense.
  Orthogonal translation of unnatural polymers
  Dr J Chin
Application Deadline: 3 December 2019

Funding Type

PhD Type

The aim of this project is to develop foundational technologies to convert the cellular protein synthesis machinery into a factory for the synthesis of unnatural polymers.
  Personal genomics - computational bioinformatics of protein structure, disorder, function and phenotype.
  Dr J Gough
Application Deadline: 3 December 2019

Funding Type

PhD Type

The age of personal genomics will soon be upon us. With large scale projects such as Genomics England and the 1,000 genomes project, plus the rapidly falling price of genomic sequencing, a significant proportion of the population will have their own personal genome partially or fully sequenced in the coming decade.
  Probing the structure and function of neural connectomes
  Dr W Schafer
Application Deadline: 3 December 2019

Funding Type

PhD Type

Connectomics offers the possibility of understanding the brain in terms of its neural components and their interactions. However, such a reductionist understanding of the brain presents many challenges.
  Reconstitution of a ciliary rootlet for cryoEM structure determination.
  Dr A Carter
Application Deadline: 3 December 2019

Funding Type

PhD Type

Cilia are found on all cells and have functions ranging from receiving signals to moving mucus out of the lungs. At their feet are basal bodies and below these are long striated filaments known as rootlets.
  Role of glutamate receptor dynamics in synaptic plasticity
  Dr I Greger
Application Deadline: 3 December 2019

Funding Type

PhD Type

Information transfer in the brain occurs at synapses, where memories are stored as a result of synaptic plasticity processes. AMPA-type glutamate-receptors (AMPARs), the main mediators of signal transmission, centrally contribute to synaptic plasticity.
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