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We have 829 Medicine PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Medicine PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 829 Medicine PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Building a toxicological screen to predict drug-induced pulmonary hypertension (RANAA_U23MRC)

Pulmonary arterial hypertension (PAH) is a debilitating, often fatal disease, affecting both children and adults, which is caused by structural changes (vascular remodelling) of pulmonary blood vessels leading to their narrowing and obliteration (PMID:15194174). Read more

Investigating the mechanisms that drive breast cancer metastasis to the brain

In recent years our understanding of the molecular basis of cancer development and evolution has improved greatly. However, there is still much to be discovered about the molecular biology that determines the spread (metastasis) of tumours to distant organs. Read more

Exploiting NLRP3-inflammasome signalling in glioblastoma to combat radiotherapy resistance

  Research Group: The Patrick G Johnston Centre for Cancer Research
Brain tumours are the leading cause of cancer deaths in children and adults under the age of 40. High-grade Gliob lastoma is treated by surgery followed by chemo/radiotherapy but recurs in the majority of patients and new treatments need to be developed. Read more

MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

Circadian rhythms and sleep are evolutionarily conserved from fruit flies (Drosophila) and are fundamental as well as vital to biology and health (Jagannath et al., 2017; Menet and Rosbash, 2011). Read more

Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Assessing the impacts of targeting mRNA translation machinery on metabolic fitness and treatment response of glioblastoma cancer cells

  Research Group: The Patrick G Johnston Centre for Cancer Research
The current standards of care for glioblastoma are rarely curative, highlighting the urgent need for a better understanding of its biology to enhance the development of innovative therapeutic approaches. . Read more

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