University of Bristol Medicine PhD Projects, Programmes & Scholarships

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Supervisor: Prof T Gaunt

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Integrative genomics prioritisation of drug targets

University of Bristol Bristol Medical School

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Supervisor: Prof T Gaunt

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MScR - Advancing novel methods of assessing apathy-related behaviour in rodents

University of Bristol School of Physiology, Pharmacology & Neuroscience

Apathy is a multidimensional syndrome consisting of behavioural, emotional and cognitive components that ultimately lead to a loss of motivation to engage with daily life. Read more

Supervisors: Prof E S J Robinson, Dr M Jackson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- Exploring changes in well-being across key life transitions

University of Bristol School of Psychological Science

About the Project. We conduct research on the causes and consequences of positive well-being across the life course. Positive well-being includes feelings of happiness, satisfaction with one’s life, and having meaning and purpose. Read more

Supervisor: Prof C Haworth

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded MSc R- Exploring changes in well-being across key life transitions

University of Bristol School of Psychological Science

We conduct research on the causes and consequences of positive well-being across the life course. Positive well-being includes feelings of happiness, satisfaction with one’s life, and having meaning and purpose. Read more

Supervisor: Prof C Haworth

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- Interplay between environmental toxins and cancer predisposition

University of Bristol School of Cellular and Molecular Medicine

Cancer arises in part from intrinsic molecular and cellular alterations. For instance, loss of major DNA damage response genes such as BRCA1/2 has long been known to predispose individuals to multiple cancer types. Read more

Supervisor: Dr S Koh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Funded PhD - The mechanisms of cognition in bees and flies

University of Bristol School of Physiology, Pharmacology & Neuroscience

This project will be part of the Bristol-Macquarie Cotutelle Programme, funded by EPSRC. Read more

Supervisor: Prof J Hodge

1 August 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Funded PhD - Determining the genetic and circadian basis of bipolar disorder

University of Bristol School of Physiology, Pharmacology & Neuroscience

This project will be part of the University of Bristol - University of Kent Cotutelle Programme. It will be jointly supervised by Prof James Hodge (http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/) and Dr Alice French at the University of Bristol, and by Prof Gurprit Lall at University of Kent. Read more

Supervisors: Prof J Hodge, Dr AF French

12 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MScR: Probing the projections of different types of dopamine neurons

University of Bristol School of Physiology, Pharmacology & Neuroscience

What makes one neuron different from another? How can we define different “types” of cells? Are cell types important?. In Parkinson’s disease some dopamine neurons seem to be more vulnerable to neurodegeneration. Read more

Supervisor: Prof Paul Dodson

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR - Preserving t-tubule function in adult cardiac myocytes in short-term culture

University of Bristol School of Physiology, Pharmacology & Neuroscience

Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more

Supervisors: Prof A James, Dr S Harmer

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR: Involvement of astrocytes in neurological manifestations of Long COVID syndrome

University of Bristol School of Physiology, Pharmacology & Neuroscience

A significant fraction of patients affected by Long COVID, long-term consequences following acute SARS-CoV-2 infection, suffer from mental fatigue and cognitive deficits (1-3). Read more

Supervisor: Prof A Teschemacher

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD - Investigation of hypervigilance to threat in the adult rat

University of Bristol School of Physiology, Pharmacology & Neuroscience

There is a strong phylogenetic argument that the brain circuits and mechanisms underlying detection and reactions to threats to survival are well conserved between mammals. Read more

Supervisors: Dr E Cahill, Prof E S J Robinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

University of Bristol School of Physiology, Pharmacology & Neuroscience

Circadian rhythms and sleep are evolutionarily conserved from fruit flies (Drosophila) and are fundamental as well as vital to biology and health (Jagannath et al., 2017; Menet and Rosbash, 2011). Read more

Supervisor: Prof J Hodge

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR: Endosomal Trafficking Dysfunction in Astrocytes: A Roadmap to Alzheimer’s disease?

University of Bristol School of Physiology, Pharmacology & Neuroscience

Previously thought of as only a support cell for neurons, astrocytes have now been shown to play an essential role in regulating synaptic activity and regulating transmitter uptake and release. Read more

Supervisors: Prof KW Wilkinson, Dr K McMillan, Dr P Banks

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR - In vivo characterisation of novel risk genes for Alzheimers disease identified by Genome Wide Association Studies

University of Bristol School of Physiology, Pharmacology & Neuroscience

Genome Wide Association Studies (GWAS) for Alzheimer’s disease (AD) have identified a number of genes that are significantly associated with the disease (van der Kant et al., 2019). Read more

Supervisor: Prof J Hodge

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 73 University of Bristol Medicine PhD Projects, Programmes & Scholarships

University of Bristol Medicine PhD Projects, Programmes & Scholarships

We have 73 University of Bristol Medicine PhD Projects, Programmes & Scholarships

University of Bristol

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

Integrative genomics prioritisation of drug targets

MScR - Advancing novel methods of assessing apathy-related behaviour in rodents

Self-funded PhD- Exploring changes in well-being across key life transitions

Self-funded MSc R- Exploring changes in well-being across key life transitions

Self-funded PhD- Interplay between environmental toxins and cancer predisposition

Funded PhD - The mechanisms of cognition in bees and flies

Funded PhD - Determining the genetic and circadian basis of bipolar disorder

MScR: Probing the projections of different types of dopamine neurons

MScR - Preserving t-tubule function in adult cardiac myocytes in short-term culture

MScR: Involvement of astrocytes in neurological manifestations of Long COVID syndrome

Self-funded PhD - Investigation of hypervigilance to threat in the adult rat

MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

MScR: Endosomal Trafficking Dysfunction in Astrocytes: A Roadmap to Alzheimer’s disease?

MScR - In vivo characterisation of novel risk genes for Alzheimers disease identified by Genome Wide Association Studies

We have 73 University of Bristol Medicine PhD Projects, Programmes & Scholarships

University of Bristol Medicine PhD Projects, Programmes & Scholarships

We have 73 University of Bristol Medicine PhD Projects, Programmes & Scholarships

University of Bristol

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