Microbiology (manchester) PhD Projects, Programmes & Scholarships

We have 32 Microbiology (manchester) PhD Projects, Programmes & Scholarships

NMR approaches for understanding mass transfer in microbial biofilms and sessile microbial communities

The University of Manchester Department of Chemistry

Biofilms are structured sessile communities of microorganisms with relevance in many areas of life. They are almost omnipresent in aquatic and terrestrial ecosystems. Read more

Supervisors: Prof M Nilsson, Prof A McBain

Year round applications PhD Research Project Self-Funded PhD Students Only

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How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

The University of Manchester Department of Physics and Astronomy

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Supervisor: Prof J Lu

28 June 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Diagnostics for FMF patients and carrier survival in pandemics

The University of Manchester Faculty of Biology, Medicine and Health

Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more

Supervisors: Dr P Arkwright, Dr G Lopez-Castejon, Dr J Cavet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Data-driven optimal prediction of bacteria growth

The University of Manchester Department of Mechanical, Aerospace and Civil Engineering

This project is devoted to an AI-based prediction of bacteria growth and its control by antibiotics. In synthetic biology, an improved understanding of bacterial regulatory circuits is required to develop complex biological systems with functionalities beyond existing in nature [1, 2]. Read more

Supervisor: Prof R Breitling

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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The role of Human cytomegalovirus glycoprotein polymorphisms in disease pathogenesis

The University of Manchester Faculty of Biology, Medicine and Health

Human cytomegalovirus (HCMV) produces asymptomatic infection in most immunocompetent individuals but thereafter establishes life-long infection with periodic reactivation and asymptomatic shedding. Read more

Supervisors: Prof P Vallely, Prof P Klapper

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of regulatory evolution in phage ecology

The University of Manchester Faculty of Biology, Medicine and Health

The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more

Supervisors: Dr M Lagator, Dr CI Igler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Optimizing phage-antibiotic-synergies to kill bacterial pathogens

The University of Manchester Faculty of Biology, Medicine and Health

Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more

Supervisors: Prof M Brockhurst, Dr CI Igler

Year round applications PhD Research Project Self-Funded PhD Students Only

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The impact of nutritional scavenging on host-pathogen interactions, antifungal efficacy and emergence of antifungal resistance

The University of Manchester Faculty of Biology, Medicine and Health

Infections caused by Aspergillus fumigatus (Af) cause more deaths globally than any other fungal disease. Over 20 million are affected annually with four million having life threatening invasive and chronic infections with high morbidity and mortality up to 90%. Read more

Supervisors: Dr N.V.R Van Rhijn, Dr M Bromley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Eco-evolutionary dynamics of environmental microbiomes

The University of Manchester Faculty of Biology, Medicine and Health

Include details on the project, outlining the objectives, methods and potential outcomes. Include details of training/techniques to be provided. Read more

Supervisors: Prof M Brockhurst, Dr S Nixon, Dr K Coyte

15 June 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Geomicrobiological controls on radionuclide speciation and fate during the geodisposal of radioactive waste

The University of Manchester Department of Earth and Environmental Sciences

Context. The UK has been generating electricity from nuclear power for over sixty years. Consequently, the safe disposal of the UK’s existing ~750,000 m3 of radioactive waste is a clear priority. Read more

Supervisors: Prof J Lloyd, Prof S Shaw, Dr A Uknnl

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Defining the protective effects of a commensal bacterial strain in skin barrier function and protection from disease

The University of Manchester Faculty of Biology, Medicine and Health

Maintaining a healthy skin barrier is vital for our health. In response to skin wounding, we have a well-orchestrated immune response that heals the breach. Read more

Supervisors: Prof S Cruickshank, Prof A McBain, Dr R Unwin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis

The University of Manchester Faculty of Biology, Medicine and Health

Chronic pulmonary aspergillosis (CPA) is a progressive infection affecting patients with chronic lung disease. It significantly affects quality of life and mortality. Read more

Supervisors: Dr CK Kosmidis, Dr M Bromley, Dr R Richardson, Dr M Bottery, Prof T Hussell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Drug repurposing for the treatment of aspergillosis

The University of Manchester Faculty of Biology, Medicine and Health

The mould Aspergillus fumigatus was classified by the WHO as a critical priority pathogen in 2022. It causes a spectrum of invasive, allergic and chronic disease. Read more

Supervisors: Dr CK Kosmidis, Prof D Ashcroft, Dr M Bottery, Dr M Bromley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Modelling the ecology and evolution of microbial communities

The University of Manchester Faculty of Biology, Medicine and Health

From the human gut to deep-sea sediments, microbial communities – or microbiomes – colonize virtually every habitat on earth. These microbiomes are central to ecosystem functioning and to host health, and therefore it is essential that we understand how and why they change over time. Read more

Supervisors: Dr K Coyte, Dr C Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 32 Microbiology (manchester) PhD Projects, Programmes & Scholarships

Microbiology (manchester) PhD Projects, Programmes & Scholarships

We have 32 Microbiology (manchester) PhD Projects, Programmes & Scholarships

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