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We have 9 Microbiology (toxicity) PhD Projects, Programmes & Scholarships

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Microbiology (toxicity) PhD Projects, Programmes & Scholarships

We have 9 Microbiology (toxicity) PhD Projects, Programmes & Scholarships

Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

The development and application of metabolomics tools to study human metabolism in health and disease

Metabolites play many important roles in humans including through metabolism to support our growth and health, through incorporation of lipids in cell membranes to influence transport of biochemicals in to and out of cells and to regulate biochemical processes. Read more

Chaperones and the response to protein misfolding stress

Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more

Exploring Myxobacteria as live antibiotics against pathogenic bacteria

Multi-drug resistant (MDR) bacteria have been identified as a global threat to humanity, limiting therapeutic options. The search for new antibiotics lags far behind the occurrence of MDR bacteria with no new antibiotics brought to the clinic for over 15 years. Read more

Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more
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