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Microbiology (screening) PhD Projects, Programs & Scholarships

We have 31 Microbiology (screening) PhD Projects, Programs & Scholarships

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  (BBSRC DTP CASE) Intelligent Engineering of Bacterial Genomes
  Prof R Breitling, Prof E Takano
Application Deadline: 31 January 2020

Funding Type

PhD Type

The goal of this project is to establish methodology for the intelligent engineering of biological hosts for the production of high-value drugs and chemicals.
  Cloning and expression of topoisomerase genes from Trypanosoma brucei (SteverdingD-2U19SF)
  Dr D Steverding
Application Deadline: 31 May 2020

Funding Type

PhD Type

Topoisomerases (TOPs) are essential enzymes that catalysis topological changes in DNA. TOPs are pivotal to cell survival and therefore inhibitors have been developed to target these enzymes both for antimicrobial and anti-cancer chemotherapy.
  EASTBIO A synthetic biology approach to design ‘intelligent’ organoids for the study of host-microbe interactions
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr E Cachat, Dr L Boulter
Application Deadline: 5 January 2020

Funding Type

PhD Type

Organoids are self-organised, 3D structures generated in vitro from adult or pluripotent stem cells, that exhibit similar functionality as their tissue of origin.
  Precision Medicine DTP - Analysis of intestinal metagenomes using ASAR
  Prof I Goryanin, Dr S Farrington, Prof M Dunlop
Application Deadline: 8 January 2020

Funding Type

PhD Type

Additional Supervisors. Dr Anatoly Sorokin & Dr Vidya Rajasekaran. Background. Understanding risk factors to Colorectal Cancer (CRC) can aid in its prevention.
  Emerging Infectious Diseases – Surveillance and Biosecurity
  Dr N Marks, Dr P McVeigh
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. A continued increase in both the geographical range of existing pathogens and the transmission of novel pathogens into the human population poses a challenge for the effective control of emerging infectious diseases (EIDs) and biosecurity.
  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  MRC DiMeN Doctoral Training Partnership: Drug discovery to control C. difficile infections by targeting sporulation
  Dr P Salgado, Dr J Hubbard
Application Deadline: 6 January 2020

Funding Type

PhD Type

Interested in a PhD studying antibiotic resistant bacteria and explore new ways to treat drug-resistant infections? In this PhD, you will use a range of biochemistry, biophysical and structural techniques, together with molecular biology, genetics, and microbiology approached to develop new therapeutics targeting C.
  (BBSRC DTP CASE) Discovery and Engineering of Expanded Halogenases for Late Stage Enzymatic Functionalisation
  Prof J Micklefield, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

The project aims to discover and engineer novel enzymes (biocatalysts) that can affect regioselective halogenation of complex molecules enabling more efficient and environmentally sustainable production of pharmaceuticals which are urgently required to combat disease.
  (BBSRC DTP CASE) Exploitation of P450 BM3 variants for production of valuable drug metabolites
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2020

Funding Type

PhD Type

The US Food and Drug Administration (FDA) have recommended that human drug metabolites (as well as their parent drugs) should be subject to testing for safety/toxicity.
  (BBSRC DTP) Development of whole cell biocatalysts for biomass and plastic degradation
  Dr N Dixon, Prof N Scrutton, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

Two major societal challenges exist today i) how can we consumable more sustainably and ii) how can we minimise environmental contamination.
  (BBSRC DTP) Plant-based production of a vaccine against gonorrhoea
  Prof J P Derrick, Dr A Day
Application Deadline: 31 January 2020

Funding Type

PhD Type

The sexually transmitted disease gonorrhoea is caused by the Gram-negative bacterium Neisseria gonorrhoeae. N. gonorrhoeae is a close relative of Neisseria meningitidis, which causes meningococcal meningitis.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Bacterial cell-cell interactions in microbial communities
  Dr B. Ho
Application Deadline: 31 December 2019

Funding Type

PhD Type

The microbiome plays a critical role in the wellbeing of its host, as microbes are involved in a number of important biological processes ranging from metabolism to immune system development.
  How does a new antimicrobial kill the fungi that invade immunosuppressed patients?
  Prof T Levine
Application Deadline: 24 January 2020

Funding Type

PhD Type

Hard-to-treat fungal infections are a growing problem both UK and worldwide (rates respectively 10,000 and 2M/year; mortality 40% and 25%).
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