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Microbiology (complex systems) PhD Projects, Programs & Scholarships

We have 44 Microbiology (complex systems) PhD Projects, Programs & Scholarships

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  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  [EPSRC - iCASE] Microbe – radionuclide interactions in legacy nuclear waste systems
  Prof J Lloyd, Prof K Morris, Prof S Shaw, Dr L Natrajan
Applications accepted all year round

Funding Type

PhD Type

Recent work in the Geomicrobiology Group at the University of Manchester has shown that microorganisms can have a controlling impact on the speciation (and hence mobility) of key radionuclides in a broad range of natural and engineered systems.
  River ecosystem responses to glacier loss
  Prof L Brown, Dr D Quincey
Application Deadline: 6 January 2020

Funding Type

PhD Type

Climate change poses a considerable threat to the biodiversity of high altitude ecosystems, with Arctic alpine regions across the world already beginning to show clear responses to warming (Milner et al., 2017).
  (BBSRC DTP) Optimisation of heteromeric protein complex formation via co-ordinated mRNA localisation
  Prof M Ashe, Dr M Pool, Prof C M Grant
Application Deadline: 31 January 2020

Funding Type

PhD Type

RNA granules play key roles in cells controlling many aspects of mRNA fate. For instance, in response to stress the relocalisation of mRNAs to mRNA processing bodies (P-bodies) and stress granules facilitates the degradation or storage of unwanted or valuable mRNAs, respectively.
  EASTBIO Unravelling mechanisms controlling gene expression noise in S. cerevisiae during rapid adaptive responses and its application to biotechnology.
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr S Granneman
Application Deadline: 5 January 2020

Funding Type

PhD Type

Microbes are constantly subjected to changes in their environment and have to rapidly alter their transcriptome to adapt efficiently.
  Unravelling mechanisms controlling gene expression noise in S. cerevisiae during rapid adaptive responses and its application to biotechnology.
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr S Granneman, Prof P Swain
Application Deadline: 5 January 2020

Funding Type

PhD Type

Microbes are constantly subjected to changes in their environment and have to rapidly alter their transcriptome to adapt efficiently.
  Investigating the Causal Biological Effects on Microbial Induced Corrosion (MIC) Occurring Within Components of Advanced Maritime Systems
  Dr B Connolly
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for a full time PhD studentship in the Department of Materials at the University of Manchester. The project is supported by BAE Systems, who will provide both industrial supervision, access to research facilities and secondments during the studentship.
  Reed Bed Use Within Scotch Whisky Distilleries to Treat Wastewater: A New Toolkit to Help Maximise Performance
  Dr M Taggart, Dr B Morrissey, Dr L Maricello, Dr P Gaffney
Application Deadline: 6 January 2020

Funding Type

PhD Type

The demand for ‘greener’ wastewater treatment (WWT) is increasing globally. In particular, there is a need for more sustainable ‘passive’ approaches that do not rely so heavily (if at all) on hard engineering and continuous energy and chemical intervention/inputs.
  QUADRAT DTP: Unravelling the freshwater microbial phosphorus cycle
  Prof J Mcgrath, Dr C Gubry-Rangin, Dr J Chin, Dr B Spears
Application Deadline: 22 January 2020

Funding Type

PhD Type

Eutrophication of freshwater environments via anthropogenic phosphorus (P) input is one of the most serious global water management issues.
  Evolution and biochemistry of photosynthesis - electron transfer reactions, renewable energy production, biotechnology, and chloroplast genomes
  Prof C J Howe
Applications accepted all year round

Funding Type

PhD Type

The common theme of our work is the biochemistry and evolution of photosynthesis.
  Transport of essential nutrients across the outer membrane of a bacterial pathogen
  Dr M Thomas
Applications accepted all year round

Funding Type

PhD Type

Gram-negative bacteria possess a second membrane, the outer membrane (OM), that serves as an additional line of defence against noxious agents, including antibiotics.
  Tracking carbon and nitrogen fixing organisms in the oceanic microbiome
  Dr T Bibby, Dr P Lam, Prof W Huang
Application Deadline: 3 January 2020

Funding Type

PhD Type

Project Rationale. Complex marine microbial communities catalyze global cycling of carbon and nitrogen that regulate the Earth’s climate.
  EASTBIO: Understanding flows of biodiversity and ecosystem services between agriculture and natural forest.
  Prof D Burslem, Dr T Freitag, Dr C Gubry-Rangin, Prof J Travis
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Professor David Burslem (University of Aberdeen). https://www.abdn.ac.uk/sbs/people/profiles/d.burslem. Dr Thomas Freitag (The James Hutton Institute, Aberdeen).
  Microbial Micro-Engineers
  Dr M Mazza
Applications accepted all year round

Funding Type

PhD Type

Microorganisms occupy every crevice within global ecosystems and impact all aspects of life. However, too little is understood about their movement within physical crannies, and how they can restructure these microspaces for their own benefit.
  (BBSRC DTP) Using mathematical models to understand the role of the respiratory microbiome in asthma
  Research Group: Molecular Environmental Sciences
  Dr T Gilman, Dr M Muldoon, Prof N Papadopoulos, Prof D Robertson
Application Deadline: 31 January 2020

Funding Type

PhD Type

Most of the cells in the human body are not human. There are rich microbial communities (i.e., microbiota) in our digestive tracts, our respiratory tracts, and on our skin.
  EASTBIO A synthetic biology approach to design ‘intelligent’ organoids for the study of host-microbe interactions
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr E Cachat, Dr L Boulter
Application Deadline: 5 January 2020

Funding Type

PhD Type

Organoids are self-organised, 3D structures generated in vitro from adult or pluripotent stem cells, that exhibit similar functionality as their tissue of origin.
  The CRISPR system of the human pathogen Mycobacterium tuberculosis
  Research Group: Biomedical Sciences Research Centre
  Prof M F White
Application Deadline: 6 January 2020

Funding Type

PhD Type

CRISPR is a prokaryotic adaptive immune system, allowing detection and degradation of invading viruses. For the public and much of the scientific community, CRISPR is now synonymous with the minimal Class 2 systems Cas9 and Cas12.
  Control of antibiotic production through synthetic biology of bacterial hormone signalling
  Prof E Takano, Prof R Breitling
Applications accepted all year round

Funding Type

PhD Type

There is an urgent need for new antibiotics due to an increase in antibiotic resistance. To produce these essential drugs efficiently in biotechnological systems, we need to have a better understanding of the regulatory mechanisms of antibiotic production.
  PhD student position (f/m/d) in a research project analyzing the "Communication between neutrophilic granulocytes and other cells of the innate and adaptive immune system"
  Dr L Erpenbeck
Application Deadline: 31 December 2019

Funding Type

PhD Type

The Clinic for Dermatology, Venerology and Allergology offers as soon as possible a PhD student position (f/m/d) in a research project analyzing the "Communication between neutrophilic granulocytes and other cells of the innate and adaptive immune system" limited for 3 years, 19,25 h/week (50%).
  Microbe-microbe warfare in the phyllosphere
  Dr G Kettles
Application Deadline: 6 January 2020

Funding Type

PhD Type

Plant pathogens pose major challenges to the production of crops and in the resilience of our trees and forests. How we protect plants from their most damaging pathogens is therefore vital to a future of sustainable agriculture within a healthy ecosystem.
  Tree microbiomes in a changing climate
  Dr G Kettles
Application Deadline: 6 January 2020

Funding Type

PhD Type

Plant pathogens pose major challenges to the production of crops and in the resilience of our trees and forests. How we protect plants from their most damaging pathogens is therefore vital to a future of sustainable agriculture within a healthy ecosystem.
  Chronic Wounds and Infection - impact on diabetic patients
  Research Group: Centre for Skin Sciences
  Dr M J Thornton, Dr J N Fletcher
Applications accepted all year round

Funding Type

PhD Type

Non-healing chronic wounds present a significant clinical challenge. In Europe, the cost of wound management accounts for 2%–4% of the health care budget and the complications associated with impaired wound healing can have a significant, long-term effect on the morbidity, mortality, and quality of life for patients.
  Identification of the Trypanosoma brucei transferrin receptor-recognition site of transferrin (SteverdingDU19SF)
  Dr D Steverding
Application Deadline: 31 May 2020

Funding Type

PhD Type

The transferrin receptor of the protozoan parasite Trypanosoma brucei (TbTfR) is a heterodimeric protein complex encoded by two expression site associated genes, ESAG6 and ESAG7, which shows no homology to the homodimeric human transferrin receptor (hTfR).
  Advancing engineering and gene circuits approaches to regulate metabolism in productive, fast-growing cyanobacterial strains
  Research Group: Institute of Molecular Plant Sciences
  Dr A McCormick, Dr Baojun Wang
Application Deadline: 5 January 2020

Funding Type

PhD Type

Cyanobacteria are an important phylum of photosynthetic microbes that can convert captured CO2 into a wide variety of complex organic molecules.
  EASTBIO Molecular basis of environmental sensing in fungi and protozoan parasites
  Research Group: Institute of Immunology & Infection Research
  Dr J Thompson, Dr J Baranovic, Dr E Wallace
Application Deadline: 5 January 2020

Funding Type

PhD Type

Many of the unicellular eukaryotic parasites that cause disease in humans are exquisitely adapted to navigate the complex and dynamic environments that they encounter in their hosts in order to sustain their life cycles and spread infection.
  Obtaining mechanistic insights into interplay of multiple effectors of oncogenic RAS molecules
  Dr K Tanaka, Dr A Revyakin
Application Deadline: 12 January 2020

Funding Type

PhD Type

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. Importantly, about 20% of all human cancers harbour mutations in RAS genes (COSMIC).
  *EASTBIO* Impact of the microbiome on development and health
  Research Group: Biomedical Sciences Research Centre
  Dr I Somorjai
Application Deadline: 5 January 2020

Funding Type

PhD Type

BBSRC Thematic Group. Frontier Bioscience. The gut microbiota - the complex community of bacteria, viruses and archaea with which we live - has an important impact on health, disease progression, lifespan and behaviour (Glendinning and Free 2014).
  Unravelling the global microbiome of crop plants to improve sustainability and food security
  Prof G Bending, Dr C Quince
Application Deadline: 12 January 2020

Funding Type

PhD Type

Plants live in close association with complex communities of microbes which together constitute their ‘microbiome’. The microbiome interacts with the plant in numerous ways; some microbes are beneficial and promote plant growth, while others are pathogens which reduce crop yields.
  Quantitative Risk Assessment for Food Safety (allergens, microbial pathogens or chemical contaminants)
  Prof N Strachan, Dr F Perez-Reche
Applications accepted all year round

Funding Type

PhD Type

This project will use computational methods to assess risks. An expectation of the society we live in is that the food that we eat is safe.
  QUADRAT DTP: Environmental change and the epidemiology of a multi-host pathogen: Leptospira in Africa
  Dr M Moseley, Prof E Morgan
Application Deadline: 22 January 2020

Funding Type

PhD Type

Multi-host pathogens include some the most important pathogens of livestock and humans. These pathogens are maintained in complex ecological reservoirs that are comprised of epidemiologically connected animal host populations and environments (Viana et al., 2014).
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