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Microbiology (infection biology) PhD Projects, Programs & Scholarships

We have 77 Microbiology (infection biology) PhD Projects, Programs & Scholarships

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  A proteomic map of host cell rewiring by pathogens
  Dr B Collins, Prof J Bengoechea, Dr G Schroeder
Application Deadline: 31 March 2020

Funding Type

PhD Type

We aim to develop advanced methods in mass spectrometry-based proteomics and apply them to the question of how host cellular defences are manipulated by bacterial pathogens.
  Development of an in vitro model to dissect the mechanism of fungal persistence in the cystic fibrosis lung
  Prof P Bowyer, Dr M Bromley, Dr S Gago
Application Deadline: 28 February 2020

Funding Type

PhD Type

Cystic fibrosis (CF) is the most common fatal genetically inherited disease in Caucasian populations. This disease is caused by mutations in the cystic fibrosis transmembrane regulator gene (CFTR) which produces defective ion fluxes and calcium homeostasis in the epithelia.
  Deciphering Aspergillus fumigatus - Pseudomonas aeruginosa synergistic interactions in coinfection
  Dr J Amich, Prof E Bignell, Dr S Fowler
Applications accepted all year round

Funding Type

PhD Type

Pathogen-pathogen interactions in polymicrobial infections are known to directly impact, often to worsen, disease outcomes. Aspergillus fumigatus is the most common fungal pathogen and Pseudomonas aeruginosa one of the most prevalent bacterial pathogens of the human lung.
  (WIS) How food-borne Listeria monocytogenes overcomes the host defence mechanisms at the single cell level?
  Prof I Roberts, Dr P Paszek
Application Deadline: 6 March 2020

Funding Type

PhD Type

Pathogens have developed intricate ways to overcome the host’s immune system. In this proposal we will study the direct interaction of macrophages with the important food-borne bacterial pathogen Listeria monocytogenes that causes significant human morbidity and mortality.
  Understanding the role of DRAM in infection and autophagy-related disease
  Dr J King, Dr P Elks
Applications accepted all year round

Funding Type

PhD Type

Intracellular degradation by lysosomes is important in a wide range of diseases. The capture and degradation of cytoplasmic components by autophagy allows tumour cells to survive starvation and neurons to remove the protein aggregates associated with neurodegeneration.
  Nanoparticle delivery of antibiotics for treatment of pulmonary infection
  Dr V Kett, Dr M Tunney
Applications accepted all year round

Funding Type

PhD Type

In respiratory diseases such as Cystic Fibrosis (CF) and COPD, the lungs are colonized by diverse polymicrobial bacterial communities.
  MRC DTP 4 Year PhD Programme: Cell biology of a bacterial nano-weapon
  Dr S Coulthurst, Dr C Rickman
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Iron Biology
  Prof H Drakesmith, Dr O Bannard
Application Deadline: 24 July 2020

Funding Type

PhD Type

We study how iron and anaemia influence immunity and infectious diseases. Our research inspires therapies that control iron physiology to improve immunity, combat infections and treat disorders of iron metabolism.
  Iron Biology
  Prof H Drakesmith, Dr O Bannard
Application Deadline: 24 July 2020

Funding Type

PhD Type

We study how iron and anaemia influence immunity and infectious diseases. Our research inspires therapies that control iron physiology to improve immunity, combat infections and treat disorders of iron metabolism.
  Analysis and Treatment of Orthopaedic Pin Site Infections
  Dr J McEvoy
Applications accepted all year round

Funding Type

PhD Type

Pin site infections are a major complication of external fixation of fractures, and bacterial biofilms are known to form on the pin surface.1 This project, in collaboration with Dr Shobana Dissanayeke (RHUL) and St Peter’s Hospital, Chertsey, will investigate bacterial biofilms that have been obtained from percutaneous pins used in orthopaedic fixation frames.
  How does Vaccinia virus evade detection by the innate immune system?
  Dr L Unterholzner, Dr M Munir
Application Deadline: 2 March 2020

Funding Type

PhD Type

Background. Most of our cells are able to detect when they have been infected by a virus.
  EMBL Australia Partnership PhD Program

Funding Type

PhD Type

Undertake interdisciplinary, postgraduate research for a PhD degree at Australia's top life science laboratories. Successful students will receive generous scholarships and travel grants while undertaking their PhD at an EMBL Australia laboratory in Melbourne, Sydney, Canberra or Adelaide.
  Virulence factors in dermatophytes
  Dr A Bolhuis
Applications accepted all year round

Funding Type

PhD Type

Dermatophytosis is caused by fungi infecting keratinised tissues and represents the most common and disseminated group of mycoses.
  Defining strategies to promote immunity to multi-drug resistant Staphylococcus aureus.
  Dr L Prince
Applications accepted all year round

Funding Type

PhD Type

Staphylococcus aureus is a highly successful pathogen that can circumvent many aspects of immunity. White blood cells, including neutrophils, are a critical defence against infection and yet S.
  The chemical glycobiology of carbohydrate metabolism
  Prof R Field, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Carbohydrates are widespread in nature and fulfil many important biological functions. However, the biology of carbohydrates is much less well explored than that of nucleic acids and proteins.
  The respiratory metagenome during exacerbations of asthma
  Prof N Papadopoulos, Prof D Robertson, Dr S Megremis
Applications accepted all year round

Funding Type

PhD Type

Asthma is an international pandemic, with 10% or more of the global population having experience asthma symptoms some time in life.
  FoodBioSystems DTP - A novel approach for reducing multiple-drug resistance in foodborne bacteria: application of CRISPR technology
  Prof S C Andrews, Prof RM La Ragione, Dr C Rymer
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP.
  The contribution of human mast cells to innate functional memory in anti-bacterial responses
  Prof S Bulfone-Paus, Dr J Cavet
Applications accepted all year round

Funding Type

PhD Type

In the recent years, it has become evident that after infection or vaccination innate immune cells have the capacity to adapt and modify the nature of their activities following a single immunostimulatory challenge and display a long-term functional memory.
  How does the human gut microbiota protect against infection with enterohaemorrhagic E. coli? (SchullerS-NarbadAU19SF)
  Dr S Schüller, Prof A Narbad
Application Deadline: 31 May 2020

Funding Type

PhD Type

The human body is populated by trillions of commensal bacteria (microbiota), most of which reside in the intestine and have established a symbiotic relationship with the host.
  The role of pore-forming bacterial proteins in pneumonia and meningitis
  Prof T J Mitchell, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

The bacterium Streptococcus pneumoniae (the pneumococcus) is carried in the nasopharynx of most children and some adults without causing disease.
  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Dr T Darton
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  Functional analysis of novel genes important in the physiology and pathogenesis of the human pathogen Campylobacter jejuni
  Prof D J Kelly
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni and E. coli are the commonest cause of human bacterial gastroenteritis worldwide. Although pathogenic in humans, C.
  Adaptation to oxidative stress in hepatitis C virus persistence: the role of IRES-dependent translation.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

Hepatitis C virus (HCV) causes a clinically important disease affecting 3% of the world population (Chan 2014). About 75% of the infection will develop into chronic hepatitis, which can then progress into fibrosis, cirrhosis and hepatocellular carcinoma.
  Probing the organization and function of bacterial toxin-antitoxin complexes
  Dr F Hayes, Prof J P Derrick
Applications accepted all year round

Funding Type

PhD Type

Bacterial toxin-antitoxin (TA) modules typically consist of a pair of genes that encode for a stable toxin protein and an unstable cognate antitoxin molecule.
  Regulation of intestinal immune responses to commensal bacteria by innate lymphoid cells
  Dr M Hepworth, Prof K Else
Applications accepted all year round

Funding Type

PhD Type

Commensal bacteria present in the gastrointestinal tract provide beneficial roles for the host, such as supporting nutrient metabolism.
  Employing molecular virology to investigate hepatitis E virus replication (fully-funded PhD)
  Research Group: School of Molecular and Cellular Biology
  Dr M.R. Herod, Prof M Harris
Application Deadline: 27 February 2020

Funding Type

PhD Type

Hepatitis E virus (HEV), is a major causative agent of acute, severe hepatitis. The infection can also be chronic, particular in immunocompromised people, and fatal in pregnant women or those with existing liver diseases.
  The Eco-Immunology of Wild Mice
  Prof M Viney
Applications accepted all year round

Funding Type

PhD Type

The immune responses that wild animals make contribute to their fitness, but what those immune responses are – and how they differ from those of laboratory animals – is hardly known.
  FoodBioSystems DTP - Tackling antimicrobial resistance in dairy production: using microfluidics and smartphone technology to monitor resistance genes alongside functional antibiotic sensitivity testing
  Dr A Edwards, Prof RM La Ragione, Dr P Ray
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP. PROBLEM - Dairy farming is a socially and economically important sector of agriculture, and also illustrates the importance of a ‘one health’ approach that addresses both human and animal health.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
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