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Microbiology (screening) PhD Projects, Programs & Scholarships

We have 25 Microbiology (screening) PhD Projects, Programs & Scholarships

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  Cloning and expression of topoisomerase genes from Trypanosoma brucei (SteverdingD-2U19SF)
  Dr D Steverding
Application Deadline: 31 May 2020

Funding Type

PhD Type

Topoisomerases (TOPs) are essential enzymes that catalysis topological changes in DNA. TOPs are pivotal to cell survival and therefore inhibitors have been developed to target these enzymes both for antimicrobial and anti-cancer chemotherapy.
  Precision Medicine DTP - Analysis of intestinal metagenomes using ASAR
  Prof I Goryanin, Dr S Farrington, Prof M Dunlop
Application Deadline: 6 April 2020

Funding Type

PhD Type

Additional Supervisors. Dr Anatoly Sorokin, Dr Vidya Rajasekaran & Dr Olga Vasieva from Ingenet LTd. Background. Understanding risk factors to Colorectal Cancer (CRC) can aid in its prevention.
  High-throughput discovery of novel antibiotics using synthetic microbiology
  Dr R Draheim
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year.
  Ecology and technology of microbial fuel cells
  Prof T Bell, Prof K Hellgardt
Application Deadline: 24 April 2020

Funding Type

PhD Type

Bacteria can be used to generate electricity. Electrons are produced by bacteria as they decompose organic matter (the "fuel") under anaerobic conditions, and the electricity produced can be stored in a battery or used to power instruments.
  Next-generation biosensors for real-time, enhanced sensitivity antigen detection
  Dr A Ivanov
Applications accepted all year round

Funding Type

PhD Type

The ability to measure biomarkers and trace analytes both specifically and selectively at the single- molecule level in biological fluids has the potential to transform the diagnosis, real-time screening, analyte seining for specific hazardous materials of high-profile defence interest.
  Clinical research training fellowship EPSRC-SFI Centre for Doctoral Training in Engineered Tissues for Discovery, Industry and Medicine (LifETIME)

Funding Type

PhD Type

 The CDT in Engineered Tissues for Discovery, Industry and Medicine is a partnership between the University of Glasgow, University of Birmingham, Aston University and National University of Ireland Galway.
  Transposons to discover drug resistance mechanisms and their evolutionary cost
  Prof B Kornmann
Application Deadline: 31 March 2020

Funding Type

PhD Type

A major pitfall in the generation of novel antifungal compounds is the emergence of resistance caused by strong selective pressure for mutations evading drug action.
  Bioscience for Renewable Resources for Medchem and Toward Sustainable Pharmaceutical Molecule Manufacture
  Prof R Goss
Application Deadline: 13 April 2020

Funding Type

PhD Type

There is a need for novel and renewable technologies to enable the sustainable manufacture of pharmaceuticals. Enzymes offer a matchless opportunity for selective synthesis and late stage functionalisation, they also offer a sustainable, green and cost-effective approach toward synthesis.
  Disrupting biofilm formation in nosocomial pathogens
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

A biofilm by definition is a structured community of bacterial cells enclosed in a self-produced polysaccharide matrix and adherent to an inert or living surface.
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  Bioprospecting & biotechnology - mining the Polar microbial metagenome (Ref: SF20/APP/PEARCE2)
  Prof D Pearce
Applications accepted all year round

Funding Type

PhD Type

This project seeks to exploit new and existing Polar microbial metagenomic libraries for bioprospecting and biotechnology. Using a wide range of diverse molecular techniques, we will research the distribution of particularly useful (e.g.
  Targeting the Unfolded Protein Response to Develop Novel Antimicrobial Therapies (Ref: SF20/APP/DOVER)
  Dr LG Dover
Applications accepted all year round

Funding Type

PhD Type

Microbial pathogen resistance to antibiotics is an ever growing global concern. Antibiotics generally target microbial pathways important for survival and replication.
  The synthesis and evaluation of novel esters for the detection of pathogenic microorganisms (Ref: SF20/APP/TURNBULL)
  Dr G Turnbull
Applications accepted all year round

Funding Type

PhD Type

The detection and differentiation of pathogenic microorganisms, those which cause disease in human beings and animals, routinely relies on the observation of a change of colour in the growth medium caused by the action of microbial enzymes on artificial substrates.
  Exploring the Application of REIMS to Bovine Health Monitoring and Milk Quality Analysis
  Dr S Cameron, Prof S Huws
Application Deadline: 31 March 2020

Funding Type

PhD Type

Rapid evaporative ionisation mass spectrometry (REIMS) is an ambient ionisation technique that allows for the analysis of a sample in.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Genetic analysis of the bacterial translocation machinery
  Dr D Huber
Applications accepted all year round

Funding Type

PhD Type

Every subcellular compartment in a cell contains proteins, and yet all of these proteins are initially synthesised in the same compartment.
  Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways.
  Prof N J Gay
Applications accepted all year round

Funding Type

PhD Type

This group participates in the Wellcome Trust 4 year PhD programme in Developmental biology., MRC and BBSRC Doctoral Training Programmes.
  MSc by Research Programme: Identifying key regulators of growth-arrested states in Pseudomonas aeruginosa
  Dr M Bergkessel
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Precision Medicine DTP - A step change in sensitivity of Raman spectroscopy for accurate and rapid analysis of living cells
  Dr A Downes, Dr H Yin
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Most methods of cell characterization require a destructive or invasive test, without any real-time readout.
  Genome association studies to detect genetic determinants of virulence traits of invasive meningococcal disease isolates with age stratification
  Dr C D Bayliss
Applications accepted all year round

Funding Type

PhD Type

Neisseria meningitidis is the major cause of bacterial meningitis but is also widespread as an asymptomatic coloniser of human oropharyngeal tissues.
  Understanding and dissecting microbial communities with Raman spectroscopy
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

We have shown that it is possible to label bacteria with heavy isotopes of carbon (13C) and nitrogen (15N) and this incorporation within cellular biomass of heavy isotopes has led to significant shifts in certain vibrational modes from amino acids and nucleic acids that can be readily detected with Raman spectroscopy.
  Adjuvant therapies for mupirocin-resistant bacteria
  Dr B Bonev, Dr A Cockayne
Applications accepted all year round

Funding Type

PhD Type

Multi-drug resistant Staphylococcus aureus has been able to adapt constantly to therapeutic use of antibiotics and remains an important source of clinical complications, morbidity and mortality.
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Immunity to Influenza and Ebola viruses
  Prof A Townsend
Application Deadline: 24 July 2020

Funding Type

PhD Type

This started with the investigation of T cell recognition of peptides derived from intracellular proteins of Influenza (Townsend et al 1986), that evolved into the development of a live attenuated, single cycle Influenza vaccine, based on these principles (Powell et al, 2012; Baz et al, 2015, Holzer 2018).
  Targeting intrinsic mechanisms of antibiotic resistance in bacterial pathogens
  Prof P Roach
Application Deadline: 15 May 2020

Funding Type

PhD Type

Supervisor. Prof. Peter Roach. Project description. Antimicrobial Resistance (AMR) is one of the most serious health threats globally and it is predicted that AMR bacteria will kill >10 million people by 2050.
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