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University of Sheffield, Department of Molecular Biology and Biotechnology Microbiology PhD Projects, Programs & Scholarships

We have 14 University of Sheffield, Department of Molecular Biology and Biotechnology Microbiology PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 14
  Bactofilins and the bacterial cytoskeleton
  Dr E Hoiczyk
Applications accepted all year round

Funding Type

PhD Type

Newly developed light and electron microscopy methods are revolutionising our understanding of bacterial cells. Once thought to be simple, bacteria have now been recognised at highly organised cells using many elements previously only known from eukaryotes.
  Biogenesis of the Clostridium difficile cell surface
  Dr R Fagan
Applications accepted all year round

Funding Type

PhD Type

Clostridium difficile infection (CDI) is a major cause of morbidity and mortality in our hospitals. Infection normally follows disruption of the gut normal flora by broad-spectrum antibiotic treatment.
  Development of a novel immunotoxin
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

Immunotoxins represent a form of immunotherapy whereby antibodies are used to target a toxin, usually to cancer or infected host cells.
  Dissecting the mechanisms of antibiotic resistance in Clostridium difficile
  Dr R Fagan
Applications accepted all year round

Funding Type

PhD Type

Antibiotic resistance in pathogenic bacteria is one of the greatest health challenges facing humanity today.
  Functional analysis of novel genes important in the physiology and pathogenesis of the human pathogen Campylobacter jejuni
  Prof D J Kelly
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni and E. coli are the commonest cause of human bacterial gastroenteritis worldwide. Although pathogenic in humans, C.
  Gliding motility in bacteria
  Dr E Hoiczyk
Applications accepted all year round

Funding Type

PhD Type

Motility is important for bacterial survival and facilitates colonisation and dispersal of bacteria. While swimming and type IV pili-based swarming is relatively well understood, gliding or adventurous motility, a form of surface-associated motility is still enigmatic.
  How do antibiotics kill bacteria?
  Prof S J Foster
Applications accepted all year round

Funding Type

PhD Type

Despite being a lynchpin of modern healthcare we still do not understand how cell wall active antibiotics such as penicillin and vancomycin kill growing bacteria, although several theories have been proposed.
  Investigating the molecular basis of this adhesion and the development of tetraspanin-based reagents for preventing bacterial infections
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  Photoreceptor regulation of plant development
  Dr S Casson
Applications accepted all year round

Funding Type

PhD Type

Plant growth and development is highly dependent on the light environment. Light provides energy to drive photosynthesis but light quality and quantity is also perceived by photoreceptors, which signal to regulate responses enabling plants to adapt to their environment.
  Structural and functional characterisation of a novel cyanobacterial nanocompartment
  Dr E Hoiczyk
Applications accepted all year round

Funding Type

PhD Type

Increasing efficiency is an important driving force behind cellular organization and often achieved through compartmentalization.
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