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We have 18 Microbiology (infection model) PhD Projects, Programmes & Scholarships for Self-funded Students

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Microbiology (infection model) PhD Projects, Programmes & Scholarships for Self-funded Students

We have 18 Microbiology (infection model) PhD Projects, Programmes & Scholarships for Self-funded Students

CRISPR/Cas9 probing of virulence factors in dermatophytes

One of the most widespread fungal infections affecting 20-25% of the global population is dermatophytosis. This is caused by fungi that infect the skin, nails, and hair, leading to common conditions such as athlete’s foot or ringworm. Read more

Investigating the role of lactate in tuberculosis disease

About the project. We are seeking talented, hard-working and motivated students with a passion for research in Immunology, Metabolism and Infectious diseases to join the team led by Dr Alba Llibre (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/llibre-alba.aspx). Read more

Competition and cooperation relationships within human microbial communities.

Typical studies of the human microbiome identify dysbiosis by sampling from healthy individuals, comparing them to individuals with a particular disease state, and reporting changes in the presence and/or abundance of bacterial species. Read more

The impact of nutritional scavenging on host-pathogen interactions, antifungal efficacy and emergence of antifungal resistance

Infections caused by Aspergillus fumigatus (Af) cause more deaths globally than any other fungal disease. Over 20 million are affected annually with four million having life threatening invasive and chronic infections with high morbidity and mortality up to 90%. Read more

Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

Modelling the respiratory microbiome in chronic lung disease and healthy ageing

The Respiratory Microbiome Group seeks to understand the interactions between complex communities of bacteria, fungi and viruses with the human respiratory tract in both disease (acute infections and chronic lung disease) and in health or healthy ageing. Read more

Fully funded PhD student position in structural biology of viruses

PhD position in the structural biology of viruses. The Department of Chemistry is opening a PhD position in Chemistry with a specialization in structural biology. Read more

The role of regulatory evolution in phage ecology

The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more

Developing 3D models to understand how interactions between bacterial biofilm and the host environment impact antimicrobial efficacy in a chronic infected wound

2.8 million people in the UK have a chronic wound which persist for months or years, causing pain, isolation, odour, and decreased mobility; patients with chronic wounds regularly report a deterioration in quality of life. Polymicrobial biofilms are present in greater than 70% of chronic wounds, making effective treatment incredibly challenging. Read more

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