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Molecular Biology (antibiotic) PhD Projects, Programs & Scholarships

We have 46 Molecular Biology (antibiotic) PhD Projects, Programs & Scholarships

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We have 46 Molecular Biology (antibiotic) PhD Projects, Programs & Scholarships

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Understanding Multiple Antibiotic Resistance in Gram-negative Bacteria

  Research Group: BBSRC MIBTP
Antibiotics have transformed medical practice, increased life expectancy and, together with vaccination, led to the near eradication of many bacterial diseases. Read more

Control of antibiotic production through synthetic biology of bacterial hormone signalling

There is an urgent need for new antibiotics due to an increase in antibiotic resistance. To produce these essential drugs efficiently in biotechnological systems, we need to have a better understanding of the regulatory mechanisms of antibiotic production. Read more

Understanding the effect of antibiotic combinations: a quantitative approach

  Research Group: Institute of Cell Biology
Our society is currently facing an important problem with the rise of multiple antibiotic resistant bacterial strains. As the development of new antibiotics has stalled in recent years, new strategies are urgently needed to supplement current available therapies. Read more

EASTBIO Investigating the effects of plasmid-borne mutagenic DNA polymerases on the evolution of antibiotic resistance.

  Research Group: Institute of Cell Biology
Antibiotics from the b-lactam family have been a cornerstone of both human and animal medicine but with increasing bacterial resistance to many first and second-line drugs, clinicians are forced to use b-lactams of ‘last resort’, such as carbapenems. Read more

Understanding the multiple antibiotic resistant ESKAPE pathogen Acinetobacter baumannii

  Research Group: BBSRC MIBTP
The ESKAPE pathogens, which evade most commonly used antibiotics, are a small group of bacteria, identified by the WHO in 2017, as presenting the greatest risk to global human health. Read more

Simulation-led investigation and engineering of enzymes involved in abyssomicin antibiotic biosynthesis

Enzymes are remarkable biocatalysts that allow rapid, selective and efficient catalysis under mild conditions. Biotechnology exploits the outstanding rate-enhancing properties of these natural biocatalysts to manufacture high added-value products. Read more

Dissecting the molecular mechanisms of antibiotic resistance in bacterial pathogens

  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections. Since their introduction in the middle years of the 20th Century, they have added ~10 years to the human lifespan, and have become a cornerstone of modern medicine. Read more

High-throughput discovery of novel antibiotics using synthetic microbiology

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year. Read more

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