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We have 15 Molecular Biology (cell division) PhD Projects, Programmes & Scholarships

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Molecular Biology (cell division) PhD Projects, Programmes & Scholarships

We have 15 Molecular Biology (cell division) PhD Projects, Programmes & Scholarships

Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more

MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

Cellular mechanisms of equal chromosome segregation and genome stability

The PhD project will investigate how chromosomes segregate equally in each cell division through epigenetic regulation of the centromere, and how cells respond in stress conditions to maintain genome instability. Read more

Why do cancers cells re-express meiotic SYCP1 protein?

The aim of meiosis is to generate gametes by recombining the chromosomes and reducing the genome from diploid to haploid. However, in mitosis haploid genome and recombination have catastrophic, oncogenic outcomes. Read more

Cell-matrix interface engineering for regenerative medicine applications and disease modelling

Dr. Mahetab Amer is seeking motivated students with backgrounds in tissue engineering, cell biology, materials science, or related fields to join her dynamic, multidisciplinary research group at the Division of Cell Matrix Biology and Regenerative Medicine, University of Manchester. Read more
Last chance to apply

Investigating the effect of promoters on gene expression in novel adeno-associated virus (AAV) producer cell lines.

We are seeking an enthusiastic candidate to work on an exciting and highly collaborative research project, aimed at identifying and characterising optimal promoter sequences to control expression of AAV genes to engineer novel stable AAV producer cell banks. Read more

Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

Epilepsy is a chronic neurological disease characterised by recurrent spontaneous seizures and cognitive co-morbidities. Current small molecule approaches to treating epilepsy are ineffective in a significant portion of cases, and are associated with substantial adverse effects. Read more
Last chance to apply

Impact of adeono-associated virus (AAV) formulation on utility

AAV gene therapy clinical trials are expanding to address unmet medical needs and the breadth of diseases to which AAVs are applied is increasing rapidly with over 200 trials registered globally. Read more
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