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We have 28 Molecular Biology (coding) PhD Projects, Programmes & Scholarships

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Molecular Biology (coding) PhD Projects, Programmes & Scholarships

We have 28 Molecular Biology (coding) PhD Projects, Programmes & Scholarships

Retrotransposons in immunity

Only about 1-2% of our genome is made up of protein coding genes, the rest is non-coding and at least half of that is made up of repetitive DNA sequences known as transposable elements (TEs). Read more

Development of miRNAs as a new therapeutic tool in the treatment of cardiovascular diseases

Ischemic heart diseases and their pathological consequences belong to the leading causes of death worldwide. In the acute treatment of myocardial ischemia one of the most important tasks is the restoration of the tissue perfusion. Read more

Nuclear and transcriptional dysregulations during cellular senescence

Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more

Control and inhibition of virus replication

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Understanding the role of spliceosome gene mutations in disease

The DNA of a cell is copied into a pre-messenger RNA (pre-mRNA) that the cell uses as a template for protein production. Some of the information contained in DNA is not required for making proteins, therefore, unwanted information must be removed before a protein is made. Read more

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