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Molecular Biology (diabetes) PhD Projects, Programs & Scholarships

We have 46 Molecular Biology (diabetes) PhD Projects, Programs & Scholarships

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We have 46 Molecular Biology (diabetes) PhD Projects, Programs & Scholarships

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Preferential Gq signalling in diabetes: an electrical switch in incretin action and in diabetes progression?

The progression of type 2 diabetes (T2D) involves development of insulin resistance that is frequently associated with obesity and that is initially compensated by increased insulin secretion from pancreatic β-cells. Read more

Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials

Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more

Opportunities for research studying Diabetes and Endocrinology at the University of Sheffield, Department of Oncology and Metabolism

The Department of Oncology and Metabolism, based in the Medical School, is a multidisciplinary department that has 4 main themes. The Diabetes and Endocrinology research theme has strengths in adrenal disease, diabetes, neuroendocrine tumours and drug development. Read more

Health Opportunity for Patient Empowerment in Gestational Diabetes (HOPE-GDM)

  Research Group: Chemistry and Biosciences
Gestational Diabetes is a temporary condition diagnosed at 24-28 weeks gestation, where the body is unable to maintain normal blood glucose levels due to insulin resistance during pregnancy. Read more

Understanding the aetiology of diabetic neuropathy

Diabetic neuropathy is a common secondary complication of diabetes mellitus which affects around 50% of all patients with diabetes - impacting on health, wellbeing and quality of life. Read more

Biochemical pathology of diabetes: Mechanisms of cysteine depletion during hyperglycaemia (HAMILTONC_U22SF)

In humans, the cysteine-containing tripeptide glutathione (GSH) is an essential thiol cofactor that maintains an intracellular reducing environment to protect against oxidative stress, which causes lipid, protein & DNA damage. Read more

*Eastbio*: Serum albumin glycation and its impact on Zn2+-dependent haemostasis and insulin dynamics

Zinc is an essential micronutrient in mammals, vital to virtually all physiological pathways and processes. High nanomolar concentrations of free zinc ions (Zn2+) are cytotoxic; therefore, extracellular zinc is usually well-buffered. Read more

Targeting Connexin and Pannexin channel signalling in Diabetic Retinopathy

  Research Group: Molecular Mechanisms and Long Term Conditions
Reference. SHLS20042. Diabetic retinopathy (DR) is a microvascular consequence of diabetes mellitus (both Type 1 and Type 2) affecting more than a third of diabetics (affecting an estimated 100million people worldwide). Read more

Identification of novel regulators of pancreatic beta-cell identity

Diabetes is the largest epidemic in human history that affects 1 in 12 adults worldwide. Due to our modern lifestyle, it is one of the few diseases where the incidence is set to rise dramatically, with projections putting 650 million people at risk by 2040. Read more

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