Molecular Biology (genome) PhD Projects, Programmes & Scholarships

Using genome engineering and bioinformatics to understand heterochromatin and centromere function in Schizosaccharomyces pombe and in cancer cells

University of Nottingham School of Life Sciences

Centromeres are the DNA sequences on eukaryotic chromosomes that mediate accurate chromosome segregation at both mitotic and meiotic cell divisions. Read more

Supervisors: Dr W R A Brown, Dr W Wickstead

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

University of Bristol School of Biochemistry

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more

Supervisor: Prof M D Szczelkun

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cellular mechanisms of equal chromosome segregation and genome stability

University of Southampton School of Biological Sciences

The PhD project will investigate how chromosomes segregate equally in each cell division through epigenetic regulation of the centromere, and how cells respond in stress conditions to maintain genome instability. Read more

Supervisor: Assoc Prof W.Y.K.Y. Yuen

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

Supervisor: Dr T Ly

Year round applications PhD Research Project Self-Funded PhD Students Only

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Why do cancers cells re-express meiotic SYCP1 protein?

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The aim of meiosis is to generate gametes by recombining the chromosomes and reducing the genome from diploid to haploid. However, in mitosis haploid genome and recombination have catastrophic, oncogenic outcomes. Read more

Supervisor: Dr U McClurg

Year round applications PhD Research Project Self-Funded PhD Students Only

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Disrupted SUMO signalling in epithelial cancers, implications for genome stability and response to therapy.

University of Leeds Faculty of Biological Sciences

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr A Garvin

Year round applications PhD Research Project Self-Funded PhD Students Only

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The analysis of HIF function in DNA repair and genome stability

University of Sheffield School of Biosciences

DNA damage is a factor that underlies many human diseases. Such damage results in mutations, and if such genetic alterations occur in tumour suppressor or proto-oncogenes it can lead to cancer. Read more

Supervisors: Dr F Van Eeden, Prof S El-Khamisy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

Medical Research Council (Cambridge) Mitochondrial Biology Unit

Mitochondria are dynamic organelles forming a specific network by membrane remodeling events according to cellular needs1. Mitochondria contain multiple copies of their own genome, mtDNA, a circular molecule that encodes essential proteins involved in cellular energy production. Read more

Supervisors: Dr Julien Prudent, Prof M Minczuk

16 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

University of Cambridge MRC Mitochondrial Biology Unit

Mitochondria are dynamic organelles forming a specific network by membrane remodeling events according to cellular needs1. Mitochondria contain multiple copies of their own genome, mtDNA, a circular molecule that encodes essential proteins involved in cellular energy production. Read more

Supervisors: Dr Julien Prudent, Prof M Minczuk

16 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Leveraging Functional Genomics to Understand Mitonuclear Combinations in Leber Hereditary Optic Neuropathy (Ref: FFS24/HLS/APP/WINTER)

Northumbria University Faculty of Health and Life Sciences

Mitochondria are small structures present in every cell of our body, which convert the food we eat into an energy source that cells can use. Read more

Supervisors: Dr M Winter, Prof M Lako, Dr G Hilgen

25 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the biology and utility of Giant Viruses (Jumbo-bacteriophages). (ref: SF22/HLS/APP/Smith-Nelson)

Northumbria University Faculty of Health and Life Sciences

The bacteriophage research group at Northumbria University are seeking a highly motivated and talented PhD candidates to join our team and investigate the biology and potential applications of jumbo bacteriophages. Read more

Supervisor: Prof D Smith

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding L1 ORF1p and Pin1 interaction to exploit it as a therapeutic strategy for liver cancer (ref: SF22/HLS/APP/SHUKLA)

Northumbria University Faculty of Health and Life Sciences

Primary liver cancer, predominantly hepatocellular carcinoma (HCC), is the 4th commonest cause of cancer death globally. Read more

Supervisor: Dr R Shukla

Year round applications PhD Research Project Self-Funded PhD Students Only

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Natural products in bacterial physiology and chemical interaction

University of Leicester Department of Genetics and Genome Biology

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

Supervisors: Dr C Jenul, Prof D Jones

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Identification of novel genes involved in fovea formation

St George’s, University of London Medical and Biomedical Education Institute

Visual acuity depends on the fovea, located at the back of the retina, in the centre of a structure called the macula. Read more

Supervisors: Dr A Pittman, Dr FC Cavodeassi, Dr GG Gestri

26 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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FAIROmics - PhD fellowship in plant-based food fermentation genomics.

INRAE Inrae - Paris-Saclay Food and Bioproduct Engineering Research Unit

About the Project. Plant-based dairy and meat alternatives have grown in popularity in recent years for various reasons, including sustainability and health benefits, as well as lifestyle trends and dietary restrictions. Read more

Supervisors: Dr MWB Wells-Bennik, Dr HB Bachmann, Dr EH Hester, Prof M Zwietering, Prof VV Valdramidis, Dr MD Dasenaki, Dr KA Karatzas

15 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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We have 91 Molecular Biology (genome) PhD Projects, Programmes & Scholarships

Molecular Biology (genome) PhD Projects, Programmes & Scholarships

We have 91 Molecular Biology (genome) PhD Projects, Programmes & Scholarships

Using genome engineering and bioinformatics to understand heterochromatin and centromere function in Schizosaccharomyces pombe and in cancer cells

Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

Cellular mechanisms of equal chromosome segregation and genome stability

MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

Why do cancers cells re-express meiotic SYCP1 protein?

Disrupted SUMO signalling in epithelial cancers, implications for genome stability and response to therapy.

The analysis of HIF function in DNA repair and genome stability

Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

Leveraging Functional Genomics to Understand Mitonuclear Combinations in Leber Hereditary Optic Neuropathy (Ref: FFS24/HLS/APP/WINTER)

Investigating the biology and utility of Giant Viruses (Jumbo-bacteriophages). (ref: SF22/HLS/APP/Smith-Nelson)

Understanding L1 ORF1p and Pin1 interaction to exploit it as a therapeutic strategy for liver cancer (ref: SF22/HLS/APP/SHUKLA)

Natural products in bacterial physiology and chemical interaction

Identification of novel genes involved in fovea formation

FAIROmics - PhD fellowship in plant-based food fermentation genomics.

We have 91 Molecular Biology (genome) PhD Projects, Programmes & Scholarships

Molecular Biology (genome) PhD Projects, Programmes & Scholarships

We have 91 Molecular Biology (genome) PhD Projects, Programmes & Scholarships

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