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Molecular Biology (kingston) PhD Projects, Programs & Scholarships

We have 12 Molecular Biology (kingston) PhD Projects, Programs & Scholarships

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  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  Role of telomere attrition in cardiometabolic disease risk
  Dr J Buxton, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Common conditions such as Type 2 diabetes (T2D) and coronary artery disease (CAD) are complex disorders caused by a myriad of interacting genetic and lifestyle factors.
  The role of matrix interactions in regulating the SPARC family of matricellular proteins.
  Dr N Hill, Dr A Munasinghe
Applications accepted all year round

Funding Type

PhD Type

The SPARC family of matricellular proteins determine the way in which cells respond to their extracellular environment. SPARC family proteins interact with a range of binding partners, including matrix proteins (1).
  Role of RNA decay SKI complex in telomere maintenance, DNA damage response and human THES syndrome.
  Research Group: Telomere Replication & Stability
  Dr J B Vannier, Dr R Porreca
Application Deadline: 1 December 2019

Funding Type

PhD Type

During DNA replication multiple factors are transiently recruited to facilitate the movement of the replisome, especially when the replication forks are hindered by DNA secondary structures (T-loop, G4, RNA/DNA hybrids) or protein/DNA complexes (Zimmermann et al.
  Beta cell regeneration for diabetes therapy
  Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Stem cells hold great potential for the creation of artifical insulin-producing beta cells to treat diabetes. Matrix and matricellular components play a critical role in supporting the differentiation of stem cells into mature, functional beta cells.
  Characterisation of the role of Panx1/Panx2 in primary endothelial cells
  Dr M Boumechache
Applications accepted all year round

Funding Type

PhD Type

Pannexins are a family of proteins that are evolutionary related to the gap-junction forming proteins, innexins (1). Three members have been identified, Panx1, Panx2 and Panx3, and they show distinct tissue distribution.
  Comparative genomic analysis of variant features within the Neisseria spp.
  Dr L Snyder
Applications accepted all year round

Funding Type

PhD Type

The availability of rapid genome sequencing had generated an explosion of bacterial genome sequence data, much of which has not been fully explored and investigated.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  Investigating metabolic changes in neurodegeneration
  Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round

Funding Type

PhD Type

This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
  Involvement of P2X7 receptors in cancer
  Dr E Polycarpou
Applications accepted all year round

Funding Type

PhD Type

The P2X receptors are a family of ligand-gated receptor channels activated by ATP and other extracellular nucleotides. A member of this family, the P2X7 purinergic receptor has been shown to play a crucial role in various physiological and pathophysiological processes.
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