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We have 31 Molecular Biology (metastasis) PhD Projects, Programmes & Scholarships

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Molecular Biology (metastasis) PhD Projects, Programmes & Scholarships

We have 31 Molecular Biology (metastasis) PhD Projects, Programmes & Scholarships

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis

Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more

Driving phenotypic plasticity and metastasis in small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Underlying this aggressiveness is intra-tumoural heterogeneity driven by phenotypic plasticity wherein tumour cells transition from a neuroendocrine (NE) to a non-neuroendocrine (non-NE) phenotype. Read more
Last chance to apply

Treatment of Breast Cancer and Preventing Relapse

The doctoral candidate (DC) The DC will perform biological basic research on cancer in vitro and in vivo at the CIMUS-University of Santiago de Compostela (Spain). Read more

(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more
Last chance to apply

Genomic actions of RAR and VDR ligands

The Doctoral Candidate (DC) will determine whether the combination of RARγ antagonist and VDR agonist is suitable as a differentiation therapy against acute myeloid leukaemia (AML). Read more
Last chance to apply

Sensitizing AML cells to RAR and VDR ligands (vitamin A and D derivatives) to prevent leukaemia relapse

The doctoral candidate (DC) will perform basic research on leukaemia cell biology in vitro and in vivo at the Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel. Read more

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