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Molecular Biology (proteomic) PhD Projects, Programs & Scholarships

We have 19 Molecular Biology (proteomic) PhD Projects, Programs & Scholarships

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  Elucidation of the role of newly discovered post-translational modification of proteins involved in hypoxia signalling using proteomic analysis and live cell imaging
  Dr V See, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

The hypoxia signalling pathway is required for the adaptation of cells to a low oxygen environment, which cells can experience in various physiological and pathological circumstances related to high altitude, development, wound healing and cancer.
  (MRC CASE) Analysis of Advanced Motion Kinetics and Kinematics, Correlated with Proteomic Approach to Biological Assessment of the Joint to Develop Optimised Personalised Knee Arthroplasty Surgery and Rehabilitation
  Ms L Biant, Prof T Freemont, Dr C Milner
Application Deadline: 14 June 2019

Funding Type

PhD Type

This project runs at the interface of biomedical engineering, cell biology and clinical orthopaedic surgery. It is a directly translatable project that allows the student to develop skills applicable to a variety of disciplines and also experience with patient interaction.
  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  Proteomic analyses of adhesion signalling in cancer
  Prof M J Humphries, Dr C Jorgensen
Applications accepted all year round

Funding Type

PhD Type

Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation, and they underpin a metazoan (multicellular) existence.
  Impact of alternative mRNA splicing on the human proteome
  Dr V Wickramasinghe, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

Alternative splicing of RNA transcripts has emerged as a key mechanism for enabling biological complexity within the human genome.
  Elucidating the interplay between mitochondrial dynamics, organelle contact sites and metabolic (re)programming (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Dr J Prudent
Application Deadline: 30 June 2019

Funding Type

PhD Type

Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell.
  Molecular mechanisms of neuronal ageing in bladder and bowel neurons (ref: SF18/APP/Ranson)
  Dr R Ranson
Applications accepted all year round

Funding Type

PhD Type

Ageing results in a progressive loss of physiological function resulting in a reduced quality of life in the elderly. One of the more prevalent conditions associated with ageing is incontinence-both faecal and urinary.
  Functional analysis of fungal effector proteins in the barley/wheat powdery mildew plant-pathogen interactions.
  Dr L Bindschedler, Prof A Devoto
Applications accepted all year round

Funding Type

PhD Type

Pathogens secrete small proteins called effectors or virulence factors which are important for the successful invasion of the host.
  Determining the translational potential of the highly phosphorylated proto-oncogene PBF
  Dr V Smith
Applications accepted all year round

Funding Type

PhD Type

In order to translate the many molecular alterations now detectable in human tumours into effective clinical management we need to fully understand their impact on tumour biology.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
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