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We have 34 Molecular Biology (synthetic biology) PhD Projects, Programmes & Scholarships

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Molecular Biology (synthetic biology) PhD Projects, Programmes & Scholarships

We have 34 Molecular Biology (synthetic biology) PhD Projects, Programmes & Scholarships

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Developing synthetic microbial communities for the control of pea downy mildew

Demand for food production is increasing due to growing global population, reduced land availability for agriculture, concern over the effects of the environment on agriculture, and decreasing yield reliability because of climate change. Read more

Defining the molecular mechanisms of leukaemia chemotherapies

Chemotherapies are usually the backbone of cancer treatment for either curative or palliative patient care. Multiple therapies can be used for the same disease, with the choice of drug dependent on parameters such as the patient’s age and fitness. Read more

Optimizing phage-antibiotic-synergies to kill bacterial pathogens

Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more

Where has all of the carbon gone? Understanding the molecular mechanisms of long-term soil carbon capture

Soils, while unglamorous, form the basis of the terrestrial biosphere and are ultimately the source of the majority of the food that we eat, yet fundamental aspects of how soils form and how they store carbon are poorly understood. Read more

The role of regulatory evolution in phage ecology

The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more

Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more

Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more

How do RNA-binding proteins control splice site selection? A multi-disciplinary approach

Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more

Identification of phosphatases that inactivate the endoplasmic reticulum stress sensor Ire1

A self-funded PhD studentship is available in the group of Dr. Martin Schröder in the Department of Biosciences at Durham University to study stress signalling mechanisms originating from the endoplasmic reticulum. Read more

Novel strategies for the diagnosis and treatment of snakebites

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

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