European Molecular Biology Laboratory (Heidelberg) Featured PhD Programmes
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Molecular Biology (testing) PhD Projects, Programs & Scholarships

We have 33 Molecular Biology (testing) PhD Projects, Programs & Scholarships

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  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  The evolution of symbiosis - testing the evolutionary theory of ecological conditions driving the emergence of symbioses
  Prof M Brockhurst
Applications accepted all year round

Funding Type

PhD Type

Symbiosis allows organisms to gain novel functions and exploit new ecological niches through the merger of once independent species.
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
  PhD Studentship in Cancer Research - Targeting glycan sugar groups to improve the diagnosis and treatment of prostate cancer
  Dr J Munkley
Application Deadline: 29 April 2020

Funding Type

PhD Type

Number of awards. 1. Start date and duration. 28 September 2020. 3 Year PhD. Overview. This PhD project will explore if glycan sugars can be exploited to improve the diagnosis and treatment of prostate cancer.
  Population-wide predictive pharmacogenomics for targeted RNA-cleaving and genome editing therapeutics (GEdit-SEQ) (Ref: SF20/APP/MOSCHOS3)
  Dr S Moschos
Applications accepted all year round

Funding Type

PhD Type

In the last decade a sleuth of interventions based on gene therapy and oligonucleotide therapeutics have received regulatory approval, paving the way for the era of personalised and N-of-1 medicine.
  Snake venomics and the quest for universally efficacious antivenoms (Ref: SF20/APP/MOSCHOS5)
  Dr S Moschos
Applications accepted all year round

Funding Type

PhD Type

Snakebite and envenomation is a WHO-declared neglected tropical disease plagues 5.5 million victims globally per year, causing nearly 150,000 deaths and 400,000 permanent disabilities.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round

Funding Type

PhD Type

The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Epigenetic mechanisms of phenotypic plasticity and the evolution of adaptive responses
  Dr R Hager, Prof J McInerney
Applications accepted all year round

Funding Type

PhD Type

We now live in a world of rapidly changing environmental conditions where species will need to adapt or perish. While populations may evolve in response to environmental change, more rapid responses may happen through processes like phenotypic plasticity.
  Effect of nanoparticles on cellular conditions in lymphocytes and germ cells in vitro
  Research Group: Chemistry and Biosciences
  Prof D Anderson, Dr M Najafzadeh
Applications accepted all year round

Funding Type

PhD Type

The use of metals such as silver (Ag), gold (Au) and copper (Cu) as nanoparticles (NPs) and other chemicals such as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (Najafzadeh et al., 2016) in medical and lifestyle applications has exponentially increased in recent years, yet little is still known about their impact on DNA and RNA in somatic as well as in germ cells (Habas et al 2018).
  Precision Medicine DTP – Development of clinically relevant models of undifferentiated pleomorphic sarcoma using a genetic screening approach
  Research Group: Edinburgh Cancer Research Centre
  Prof V Brunton, Dr L Boulter, Dr M Taylor, Prof D M Salter
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Sarcomas are relatively uncommon cancers thought to arise from pluripotent mesenchymal stem cells. Undifferentiated pleomorphic soft tissue sarcoma (UPS), though one of the commonest sarcoma subtypes encountered, exemplify the limitations of historical progress in sarcoma therapy.
  High-throughput discovery of combination therapies and engineering of CRISPR/therapeutic proteins
  Dr A Wong
Applications accepted all year round

Funding Type

PhD Type

Our lab is interested in developing and applying state-of-the-art combinatorial genetics technologies to decipher the mechanisms behind complex diseases, including cancers and neurodegenerative disorders, and discover novel combination therapies.
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  Using next-generation sequencing and CRISPR-Cas9 gene editing to investigate penetrance and phenotypic variation in inherited eye disease
  Dr C Toomes
Applications accepted all year round

Funding Type

PhD Type

Human inherited retinal diseases (IRDs) result from mutations in over 250 different genes, many of them implicated by the Leeds Vision Research Group (eg Panagiotou et al 2017, AJHG 100:960-968; El-Asrag et al 2015, 96:948-54).
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