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Molecular Biology (human) PhD Projects, Programs & Scholarships

We have 437 Molecular Biology (human) PhD Projects, Programs & Scholarships

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  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  Expanded potential stem cells for regenerative medicine, immunotherapy, and biotechnology
  Prof P Liu
Applications accepted all year round

Funding Type

PhD Type

Embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells) are pluripotent and thus hold great promise in regenerative medicine, studying disease mechanisms and drug discovery.
  Deciphering the mechanism of enclysis: new tools for cell biology in live human tissues.
  Dr Z Stamataki, Prof J Preece, Prof D Hodson
Application Deadline: 6 January 2020

Funding Type

PhD Type

Background. We recently discovered that hepatocytes, epithelial cells that make up 80% of the liver, can preferentially engulf and delete T cell subsets that dampen inflammation (regulatory T cells, Tregs).
  De Novo Mutations and Human Disease
  Prof A Goriely, Prof A Wilkie
Application Deadline: 10 January 2020

Funding Type

PhD Type

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis.
  De Novo Mutations and Human Disease
  Prof A Goriely, Prof A Wilkie
Application Deadline: 10 January 2020

Funding Type

PhD Type

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis.
  The role of ZAP in defence against human cytomegalovirus
  Dr B Strang, Dr M Goodier
Application Deadline: 1 January 2020

Funding Type

PhD Type

Determining the function of cellular anti-viral factors is now at the forefront of virology and immunobiology because these. factors are now known to shape how viruses interact with human populations.
  How does the human gut microbiota protect against infection with enterohaemorrhagic E. coli? (SchullerS-NarbadAU19SF)
  Dr S Schüller, Prof A Narbad
Application Deadline: 31 May 2020

Funding Type

PhD Type

The human body is populated by trillions of commensal bacteria (microbiota), most of which reside in the intestine and have established a symbiotic relationship with the host.
  A human ’mini-gut-on-a-chip’ to study microbial-epithelial cell interactions (SAEEDU20DTP)
  Dr A Saeed, Dr M R Williams
Application Deadline: 25 November 2019

Funding Type

PhD Type

Human organoids are 3D fragments of adult tissues and ideally conserve all of the (stem) cell types and recapitulate all of the (patho)physiological processes associated with human health and disease.
  MRC four-year PhD programme in Human Genetics, Genomics and Disease

Funding Type

PhD Type

Applications are invited from outstanding candidates to join an MRC funded 4-year multi-disciplinary PhD programme in Human Genetics, Genomics and Disease at the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  Understanding and predicting disease-associated mutations in dynamic and disordered regions of proteins
  Research Group: MRC Human Genetics Unit
  Dr J Marsh
Application Deadline: 13 December 2019

Funding Type

PhD Type

Applications are invited from outstanding candidates to join the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  Precision Medicine DTP – Integration of single-cell RNA sequencing data from human and murine kidney disease to identify novel therapeutic targets
  Research Group: Centre for Cardiovascular Science
  Dr BC Conway, Dr T Chandra, Dr D Ferenbach
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease and for end-stage kidney disease (ESRD), at which point patients require dialysis or transplantation.
  Biomarkers of Genotoxic and Reprotoxic Effects after chemical exposure in vitro in human cells
  Research Group: Chemistry and Biosciences
  Prof D Anderson, Dr M Najafzadeh
Applications accepted all year round

Funding Type

PhD Type

In human monitoring procedures, measurements obtained from endpoints to determine genetic damage are sometimes referred to as biomarkers.
  EASTBIO - Single-cell and population-level approaches to establish the impact of bone marrow adipocytes on normal human health
  Dr W Cawthorn, Dr E Theodoratou, Prof N Henderson
Application Deadline: 5 January 2020

Funding Type

PhD Type

Bone marrow adipose tissue (BMAT) is a major feature of normal human anatomy, accounting for over 10% of total fat mass in healthy humans.
  EASTBIO: Application of MinION Nanopore sequencing to understand the impact of environmental changes on sentinel indicators of ecosystem health
  Dr E Watson
Application Deadline: 5 January 2020

Funding Type

PhD Type

We are increasingly aware that human, veterinary and environmental health is intricately linked and farming and food production systems must not only be resilient to environmental changes and threats but the systems themselves must also perform with minimal environmental impact.
  Molecular mechanisms regulating the developmental plasticity of pancreatic cancer cells #NDORMS-2020/6
  Dr S Pauklin
Application Deadline: 10 January 2020

Funding Type

PhD Type

Pancreatic cancers are among the most lethal malignancies in human due to highly metastatic characteristics and the poor responsiveness to currently used cancer therapeutics.
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