Molecular Biology (protease) PhD Projects, Programmes & Scholarships

We have 9 Molecular Biology (protease) PhD Projects, Programmes & Scholarships

Characterisation of PA protease from Micrococcus luteus as a novel approach to the management of eczema

The University of Manchester Faculty of Biology, Medicine and Health

The chronic inflammatory skin disease, eczema, now affects approximately 15% of the paediatric population of the Western world and is growing in prevalence. Read more

Supervisors: Prof CN O'neill, Prof A McBain

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy

Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences

Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more

Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner

Year round applications PhD Research Project Self-Funded PhD Students Only

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Novel glycoprotease discovery and characterisation for enhanced detergent performance

Newcastle University BiSCoP CTP

In this exciting joint academia-industry project the student will exploit metagenomes and the huge untapped capacity of the human gut microbiota to breakdown glycoconjugates to discover novel protease enzymes that can potentially increase the performance and environmental sustainability of leading P&G automatic dishwashing brands. Read more

Supervisors: Dr E Lowe, Dr D Bolam, Dr AL Morales Garcia, Mrs K Bell-Rusiewicz

2 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis

Queen’s University Belfast School of Pharmacy

Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more

Supervisor: Dr R Burden

Year round applications PhD Research Project Self-Funded PhD Students Only

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Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM

University of Leeds Faculty of Biological Sciences

The BAM complex folds membrane proteins into the outer membrane of Gram-negative bacteria, proteins whose functions are essential for bacterial viability, pathogenicity and virulence. Read more

Supervisors: Prof N A Ranson, Prof S E Radford

Year round applications PhD Research Project Self-Funded PhD Students Only

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Improvements of asparaginase-based treatment for Childhood ALL

Cardiff University Cardiff School of Biosciences

Project Description. Most popular current treatments for childhood acute lymphoblastic leukaemia (ALL) in clinic are based on asparaginase (Raja et al 2012). Read more

Supervisors: Dr O V Gerasimenko, Dr J Gerasimenko

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

University of Sheffield School of Biosciences

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

Supervisor: Dr C Guo

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 9 Molecular Biology (protease) PhD Projects, Programmes & Scholarships

Molecular Biology (protease) PhD Projects, Programmes & Scholarships

We have 9 Molecular Biology (protease) PhD Projects, Programmes & Scholarships

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