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Molecular Biology (antimicrobial) PhD Projects, Programs & Scholarships

We have 39 Molecular Biology (antimicrobial) PhD Projects, Programs & Scholarships

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  Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Dr T Darton
Application Deadline: 29 January 2020

Funding Type

PhD Type

Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Exploiting the protein O-glycosylation pathway in opportunistic bacteria as a novel antimicrobial target
  Research Group: Centre for Experimental Medicine
  Prof M Valvano, Dr G Lopez-Campos
Application Deadline: 20 January 2020

Funding Type

PhD Type

Antibiotic resistance is a global health problem of epidemic proportions, especially for infections caused by Gram-negative bacteria.
  Understanding and combatting antimicrobial resistance plasmids
  Dr M Buckner, Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a major crisis for human medicine. Globally, untreatable bacterial infections are rapidly increasing, leaving us with limited treatment options.
  (BBSRC DTP) Novel antimicrobial discovery using high-throughput pathway assembly and robotics
  Prof E Takano, Prof A Munro, Prof R Breitling
Application Deadline: 31 January 2020

Funding Type

PhD Type

Recent advances in molecular biology, in particular our improved ability to read and (most importantly) write genomic sequences, have led to renewed excitement in the area of genetic engineering, i.e.
  How does a new antimicrobial kill the fungi that invade immunosuppressed patients?
  Prof T Levine
Application Deadline: 24 January 2020

Funding Type

PhD Type

Hard-to-treat fungal infections are a growing problem both UK and worldwide (rates respectively 10,000 and 2M/year; mortality 40% and 25%).
  Sharpening the blunted neutrophil response to antimicrobial resistant fungal infection
  Dr P Elks, Prof A Condliffe, Dr S Johnston
Application Deadline: 29 January 2020

Funding Type

PhD Type

Life-threatening invasive fungal infection is a major health problem in the immunocompromised, and emerging drug resistance is a major threat to global health.
  Sharpening the blunted neutrophil response to antimicrobial resistant fungal infection
  Dr P Elks, Prof A Condliffe, Dr S Johnston
Application Deadline: 29 January 2020

Funding Type

PhD Type

Project for inclusion in China Scholarship Council – University of Sheffield competition. More information is available at https://www.sheffield.ac.uk/postgraduate/phd/scholarships/csc.
  Resistance isn’t futile: Dissecting adaptation and antimicrobial resistance in pathogenic fungi
  Dr D Childers, Prof C Munro
Application Deadline: 31 January 2020

Funding Type

PhD Type

What will you investigate?. We have only four major classes of antifungals to treat life-threatening fungal infections, which even with treatment will claim over 1 million lives this year.
  ONE Planet DTP - Biofouling invertebrates and their larvae as vectors of antimicrobial resistance and marine pathogens. (OP20232)
  Dr N Aldred
Application Deadline: 31 January 2020

Funding Type

PhD Type

Of the many human impacts on the global ecosystem, the increasing antimicrobial resistance (AMR) of bacterial pathogens is a significant challenge.
  (BBSRC DTP) Metals and bacterial virulence: overcoming metal intoxication during infection
  Dr J Cavet, Dr D Linton, Prof J Lloyd
Application Deadline: 31 January 2020

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen, being the leading bacterial cause of human acute gastroenteritis and responsible for an estimated 0.5 billion cases each year.
  Developing new antimicrobials
  Dr T Narancic
Application Deadline: 31 January 2020

Funding Type

PhD Type

Antibiotic resistance is documented by the World Health Organisation as one of the three most important threats to human health.
  (BBSRC DTP) From mucin biochemistry to pulmonary immunity: How do mucins promote antimicrobial lung defences?
  Prof E Bignell, Prof D Thornton, Dr A Horsley
Application Deadline: 31 January 2020

Funding Type

PhD Type

Respiratory mucus plays multiple essential roles in mammalian lung function, from hydrating the epithelium and supporting gaseous exchange, to expelling inhaled particles and microbes and providing a conduit for innate and adaptive immune signaling.
  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Analysis and Treatment of Orthopaedic Pin Site Infections
  Dr J McEvoy
Applications accepted all year round

Funding Type

PhD Type

Pin site infections are a major complication of external fixation of fractures, and bacterial biofilms are known to form on the pin surface.1 This project, in collaboration with Dr Shobana Dissanayeke (RHUL) and St Peter’s Hospital, Chertsey, will investigate bacterial biofilms that have been obtained from percutaneous pins used in orthopaedic fixation frames.
  Silver ion-based antimicrobials: mechanisms of toxicity and resistance
  Dr G Mulley, Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"The emergence and persistence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of silver ions.
  Bacterial iron uptake pathways as targets for the development of novel antimicrobials
  Dr M Thomas
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance is an ever increasing problem. Presently it is estimated to be responsible for 700,000 deaths p.a. and it is predicted that this figure will rise to 10 million by 2050.
  (A*STAR) Engineering pathways to next generation antibiotics
  Prof J Micklefield, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

The provision of new antibiotics to combat antimicrobial resistance (AMR) and to treat neglected tropical diseases (NTD), which are problematic in the developing world, is a major global challenge.
  (BBSRC DTP) Discovery and Editing Pathways to New Antibiotics
  Prof J Micklefield, Prof D Leys, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

There is an urgent need for new antibiotics. The majority of antibiotics that are used to treat infectious diseases today are small molecules produced by microorganisms, called natural products, or derivatives thereof.
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  Applying Population-Level Microbiota Resistance Profiling in Skin Wounds
  Dr A Oates, Prof M Hardman, Mr G Smith
Application Deadline: 29 January 2020

Funding Type

PhD Type

This PhD project is based in Hull York Medical School. Antimicrobial resistance is recognised as a major global health and economic threat.
  Comparative genomic analysis of variant features within the Neisseria spp.
  Dr L Snyder
Applications accepted all year round

Funding Type

PhD Type

The availability of rapid genome sequencing had generated an explosion of bacterial genome sequence data, much of which has not been fully explored and investigated.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  Evolving to evolve: testing how history and community influence evolutionary potential
  Prof T Cooper
Application Deadline: 1 February 2020

Funding Type

PhD Type

The Cooper Lab studies the genetic basis of microbial adaptation, especially the role of genetic and environmental interactions in determining mutation effects.
  Mini Centre for Doctoral Training: Overcoming drug-resistant microbial infection – Targeting the power of Molecular Machines
  Dr E Main, Prof RW Pickersgill, Dr V Darbari, Dr A Kang
Application Deadline: 31 January 2020

Funding Type

PhD Type

The newly formed “Centre for Structural Medicine” (joint between the Schools of Biological and Chemical Sciences and Medicine and Dentistry) is seeking PhD applicants for their fully funded mini Centre for Doctoral Training (CDT) to start in September 2020.
  Development of a three dimensional in vitro model of the human cornea to dissect the inflammatory events associated with sight-threatening ocular pathogens
  Dr C Dobson, Dr C Maldonado-Codina, Prof P Morgan
Applications accepted all year round

Funding Type

PhD Type

The presence of microbes at the corneal surface may trigger low grade discomfort through to acute eye infection and permanent loss of vision.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Evolution Education Trust PhD project: Evolution of biocide tolerance in Klebsiella pneumoniae and its impact on antibiotic resistance and virulence
  Dr B V Jones
Application Deadline: 5 February 2020

Funding Type

PhD Type

The University of Bath is inviting applications for this PhD opportunity based at the Milner Centre for Evolution, a unique, cross-faculty research centre bridging biology, health and education.
  Ph.D. Fellowship in Intestinal Innate Immunity and Host Defense Peptides
  Dr E Cobo
Applications accepted all year round

Funding Type

PhD Type

RESEARCH. One Ph.D. position is available immediately at the University of Calgary, Canada to study gut innate immunity contributed by host defense peptides and immunoregulation in the epithelial and leukocyte cross-talking in response to microbial pathogens.
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