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We have 33 Molecular Biology (antimicrobial) PhD Projects, Programmes & Scholarships

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Molecular Biology (antimicrobial) PhD Projects, Programmes & Scholarships

We have 33 Molecular Biology (antimicrobial) PhD Projects, Programmes & Scholarships

Enzyme Cascades controlled in the Electrochemical Leaf for Discovery in Antimicrobial Strategy

Antibiotic discovery is usually aimed at single entities, for example a bacterial enzyme or efflux protein. This also means that antimicrobial resistance (AMR) mechanisms are considered in terms of the individual response, for example, mutations in a single target enzyme, affording resistance to the drug. Read more

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Identify novel approaches to combat multi drug resistant pathogens

Our research is focused on recalcitrant ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, andEnterobacter species) pathogens; especially hard-to-treat clinical isolates involved in multidrug resistance, biofilm infections and persistence. Read more

Chance or Necessity: Elucidating host adaptation in atypical Salmonella

Food security is a key sustainable development goal for the United Nations (UN) and it is estimated that more than two billion people did not have access to safe, nutritious and/or sufficient food in 2019. Read more

Optimizing phage-antibiotic-synergies to kill bacterial pathogens

Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more

High-throughput biomaterials discovery

Polymer biomaterials have revolutionised a range of areas from drug delivery, to antimicrobials, to cellular cryopreservation. There are 1000’s of possible monomer combinations, molecular weights and architectures to be explored, and even small differences can dramatically change their properties. Read more

Investigating the biology and utility of Giant Viruses (Jumbo-bacteriophages). (ref: SF22/HLS/APP/Smith-Nelson)

The bacteriophage research group at Northumbria University are seeking a highly motivated and talented PhD candidates to join our team and investigate the biology and potential applications of jumbo bacteriophages. Read more

Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Molecular dissection of horizontal gene transfer mechanisms in mycobacteria

A fully funded PhD position is available within the lab of Dr Abhinav KV at Leicester Institute of Structural and Chemical Biology (LISCB), University of Leicester, UK to carry out structural studies on large macromolecular machines that undertake horizontal gene transfer (HGT) in mycobacteria. Read more

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