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Molecular Biology (infection biology) PhD Projects, Programs & Scholarships

We have 97 Molecular Biology (infection biology) PhD Projects, Programs & Scholarships

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  Ph.D. Fellowship in Intestinal Innate Immunity and Host Defense Peptides
  Dr E Cobo
Applications accepted all year round

Funding Type

PhD Type

RESEARCH. One Ph.D. position is available immediately at the University of Calgary, Canada to study gut innate immunity contributed by host defense peptides and immunoregulation in the epithelial and leukocyte cross-talking in response to microbial pathogens.
  Development of an in vitro model to dissect the mechanism of fungal persistence in the cystic fibrosis lung
  Prof P Bowyer, Dr M Bromley, Dr S Gago
Application Deadline: 28 February 2020

Funding Type

PhD Type

Cystic fibrosis (CF) is the most common fatal genetically inherited disease in Caucasian populations. This disease is caused by mutations in the cystic fibrosis transmembrane regulator gene (CFTR) which produces defective ion fluxes and calcium homeostasis in the epithelia.
  Deciphering Aspergillus fumigatus - Pseudomonas aeruginosa synergistic interactions in coinfection
  Dr J Amich, Prof E Bignell, Dr S Fowler
Applications accepted all year round

Funding Type

PhD Type

Pathogen-pathogen interactions in polymicrobial infections are known to directly impact, often to worsen, disease outcomes. Aspergillus fumigatus is the most common fungal pathogen and Pseudomonas aeruginosa one of the most prevalent bacterial pathogens of the human lung.
  (WIS) How food-borne Listeria monocytogenes overcomes the host defence mechanisms at the single cell level?
  Prof I Roberts, Dr P Paszek
Application Deadline: 6 March 2020

Funding Type

PhD Type

Pathogens have developed intricate ways to overcome the host’s immune system. In this proposal we will study the direct interaction of macrophages with the important food-borne bacterial pathogen Listeria monocytogenes that causes significant human morbidity and mortality.
  Understanding the role of DRAM in infection and autophagy-related disease
  Dr J King, Dr P Elks
Applications accepted all year round

Funding Type

PhD Type

Intracellular degradation by lysosomes is important in a wide range of diseases. The capture and degradation of cytoplasmic components by autophagy allows tumour cells to survive starvation and neurons to remove the protein aggregates associated with neurodegeneration.
  Single-cell proteomic analysis of host-factor cleavage during norovirus infection
  Dr E Emmott, Dr M Iturriza
Applications accepted all year round

Funding Type

PhD Type

Human norovirus is a major human pathogen, and the causative agent behind ‘winter vomiting disease’. Typically, infection is self-limited, causing diarrhoea and vomiting lasting from 24-72 hours.
  PhD in cellular and structural biology - Elucidating infection at the plant-microbe interphase to define targets for crop breeding
  Dr C Voigt
Applications accepted all year round

Funding Type

PhD Type

Achieving food security is one of the most important global challenges. Crop production and yield has been increasingly threatened by plant pathogens in a rapidly changing environment.
  MRC DTP 4 Year PhD Programme: Cell biology of a bacterial nano-weapon
  Dr S Coulthurst, Dr C Rickman
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Analysis and Treatment of Orthopaedic Pin Site Infections
  Dr J McEvoy
Applications accepted all year round

Funding Type

PhD Type

Pin site infections are a major complication of external fixation of fractures, and bacterial biofilms are known to form on the pin surface.1 This project, in collaboration with Dr Shobana Dissanayeke (RHUL) and St Peter’s Hospital, Chertsey, will investigate bacterial biofilms that have been obtained from percutaneous pins used in orthopaedic fixation frames.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  MSc by Research Programme: Development of tools suited for the in vivo identification and study of protein Complexes in Phytophthora capsici, required for infection.
  Dr E Huitema
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  EMBL Australia Partnership PhD Program

Funding Type

PhD Type

Undertake interdisciplinary, postgraduate research for a PhD degree at Australia's top life science laboratories. Successful students will receive generous scholarships and travel grants while undertaking their PhD at an EMBL Australia laboratory in Melbourne, Sydney, Canberra or Adelaide.
  FoodBioSystems DTP - Can many biomarkers make light work of liver fluke parasite diagnostics?
  Dr P McVeigh, Dr R Morphew
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP. Liver fluke parasites are a pervasive economic threat on UK sheep and cattle farms.
  The chemical glycobiology of carbohydrate metabolism
  Prof R Field, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Carbohydrates are widespread in nature and fulfil many important biological functions. However, the biology of carbohydrates is much less well explored than that of nucleic acids and proteins.
  The nanoscale organisation of immune cell surfaces in health and disease
  Prof D Davis
Applications accepted all year round

Funding Type

PhD Type

Super-resolution microscopes, celebrated in the 2014 Nobel Prize for Chemistry, are one of the tools that allow us to study immune cells in unprecedented detail.
  The respiratory metagenome during exacerbations of asthma
  Prof N Papadopoulos, Prof D Robertson, Dr S Megremis
Applications accepted all year round

Funding Type

PhD Type

Asthma is an international pandemic, with 10% or more of the global population having experience asthma symptoms some time in life.
  Evolutionary insights for engineering improved globin oxygen carriers
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round

Funding Type

PhD Type

Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
  MRC DTP 4 Year PhD Programme: Functions & Applications of a Novel Stem Cell Signalling Pathway
  Dr GM Findlay, Dr M Stavridis
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Targeting E3 ubiquitin ligases with small molecules
  Prof A Ciulli, Dr S Virdee
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  How does the human gut microbiota protect against infection with enterohaemorrhagic E. coli? (SchullerS-NarbadAU19SF)
  Dr S Schüller, Prof A Narbad
Application Deadline: 31 May 2020

Funding Type

PhD Type

The human body is populated by trillions of commensal bacteria (microbiota), most of which reside in the intestine and have established a symbiotic relationship with the host.
  Determining novel molecular regulators of necrosis controlling premature cell death
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases.
  Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Dr T Darton
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  Functional analysis of novel genes important in the physiology and pathogenesis of the human pathogen Campylobacter jejuni
  Prof D J Kelly
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni and E. coli are the commonest cause of human bacterial gastroenteritis worldwide. Although pathogenic in humans, C.
  PhD-position
  Prof L Dölken
Application Deadline: 1 March 2020

Funding Type

PhD Type

At the Institute for Virology and Immunology of the University of Wuerzburg, Germany we offer a. PhD-position. within the RTG2581 (Metabolism, topology and compartmentalization of membrane proximal lipid and signalling components in infection (https://www.uni-wuerzburg.de/grk2581) starting 01.04.2020.
  Adaptation to oxidative stress in hepatitis C virus persistence: the role of IRES-dependent translation.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

Hepatitis C virus (HCV) causes a clinically important disease affecting 3% of the world population (Chan 2014). About 75% of the infection will develop into chronic hepatitis, which can then progress into fibrosis, cirrhosis and hepatocellular carcinoma.
  Probing the organization and function of bacterial toxin-antitoxin complexes
  Dr F Hayes, Prof J P Derrick
Applications accepted all year round

Funding Type

PhD Type

Bacterial toxin-antitoxin (TA) modules typically consist of a pair of genes that encode for a stable toxin protein and an unstable cognate antitoxin molecule.
  Employing molecular virology to investigate hepatitis E virus replication (fully-funded PhD)
  Research Group: School of Molecular and Cellular Biology
  Dr M.R. Herod, Prof M Harris
Application Deadline: 27 February 2020

Funding Type

PhD Type

Hepatitis E virus (HEV), is a major causative agent of acute, severe hepatitis. The infection can also be chronic, particular in immunocompromised people, and fatal in pregnant women or those with existing liver diseases.
  (WIS) Cross-talk between T cells and intestinal epithelial cells: a new type of immune synapse.
  Prof D Davis, Prof M Travis
Application Deadline: 6 March 2020

Funding Type

PhD Type

Super-resolution and other state-of-the-art microscope techniques allow us to study immune cell activity in unprecedented detail.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
  MRC DTP 4 Year PhD Programme: Deciphering the role of oxidative stress in cardiovascular disease using physiological and 3D cell models.
  Dr C Murdoch, Dr C Henderson
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
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