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Molecular Biology (medical microbiology) PhD Projects, Programs & Scholarships

We have 93 Molecular Biology (medical microbiology) PhD Projects, Programs & Scholarships

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Showing 1 to 30 of 93
  Investigating a parasite-specific gene expression mechanism for the identification of novel anthelmintic drug targets
  Dr B Mueller, Dr J Pettitt, Dr B Connolly
Application Deadline: 13 March 2020

Funding Type

PhD Type

Nematode parasites remain a major cause of neglected human disease and make significant global impacts on the health of agriculturally important animals and plants.
  The mechanism of DNA organisation mediated by cohesion and condensin
  Dr B Hu, Prof A Donaldson
Application Deadline: 13 March 2020

Funding Type

PhD Type

The DNA of all organisms must be compacted in order to store a large amount of genetic information in one cell. Compaction must be regulated to allow access of DNA replication or transcription machinery, but to enable suitable condensation for effective chromosome segregation into two daughter cells at mitosis.
  What determines tumour susceptibility to replication-inhibiting chemotherapy?
  Prof A Donaldson, Dr S R Dundas
Application Deadline: 13 March 2020

Funding Type

PhD Type

Chromosome replication and maintenance are central for cell division, and derailment of these processes is a major cause of cancer.
  High-throughput discovery of novel antibiotics using synthetic microbiology
  Dr R Draheim
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Clinical and molecular correlates of response to first line treatment in oral lichen planus
  Dr K Hijazi, Prof J Gibson
Application Deadline: 13 March 2020

Funding Type

PhD Type

Oral lichen planus is a chronic disease of the lining of the mouth that causes pain and increases the risk of oral cancer. The negative impact of oral lichen planus on quality of life has been proven.
  Determination of the function of inherited refractive error risk factor genes in the embryonic development of the eye.
  Prof L Erskine, Prof N Vargesson, Prof M Collinson
Application Deadline: 13 March 2020

Funding Type

PhD Type

Refractive errors, such as short-sightedness (myopia) and long-sightedness (hyperopia), are becoming epidemic, and in parts of southeast Asia around 80% of people have short-sight.
  Investigation of molecular mechanisms of Intellectual disability using human-brain organoids
  Dr E Kang, Dr D Berg
Application Deadline: 13 March 2020

Funding Type

PhD Type

Intellectual disability (ID) is a condition characterized by significant limitation in cognitive ability and adaptive behaviours with a disease onset before adulthood.
  Telomere integrity: How do Replication Factor C-like complexes maintain telomere length?
  Dr T Kubota, Prof A Donaldson
Application Deadline: 13 March 2020

Funding Type

PhD Type

Telomeres, the ends of eukaryotic chromosomes, play an essential role in protecting linear DNA from degradation. Derailed telomere regulation causes genome instability and has been implicated in increased rates of cellular senescence and many diseases, including cancer.
  The effect of anaesthetic neurotoxicity on the development of adult neural stem cells
  Dr D Berg, Dr E Kang
Application Deadline: 13 March 2020

Funding Type

PhD Type

Although most neurons in the mammalian brain are generated during development, certain areas possess the capacity to generate new neurons throughout life.
  Do rural-dwellers develop more aggressive breast and prostate cancer than those living in the city?
  Prof P Murchie, Prof Z Miedzybrodzka, Prof V Speirs, Dr R Vieira
Application Deadline: 13 March 2020

Funding Type

PhD Type

BACKGROUND.
  Is breast cancer more aggressive when developed by rural-dwellers compared to those living in the city?
  Prof P Murchie, Prof Z Miedzybrodzka, Prof V Speirs, Dr R Vieira
Application Deadline: 27 March 2020

Funding Type

PhD Type

BACKGROUND.
  MRC DTP 4 Year PhD Programme: Mendelian Randomisation Approaches to defining the Underlying risk factors for the Dementias.
  Dr A Doney, Dr W Meng
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MSc by Research Programme: Microbial Metal and Mineral Transformations: Significance for Metal Biorecovery and Biodeterioration
  Prof G M Gadd
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  Probing the organization and function of bacterial toxin-antitoxin complexes
  Dr F Hayes, Prof J P Derrick
Applications accepted all year round

Funding Type

PhD Type

Bacterial toxin-antitoxin (TA) modules typically consist of a pair of genes that encode for a stable toxin protein and an unstable cognate antitoxin molecule.
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  FoodBioSystems DTP - Gut bacteria and their DNA as elicitors of host beneficial responses
  Dr J Gutierrez-Merino, Dr G W Griffith, Dr H Davey
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP. The incidence of gut inflammatory disorders such as such as the post-infectious irritable bowel syndrome (PI-IBS) is increasing globally, with devastating consequences in animal production and public health.
  Development of an in vitro model to dissect the mechanism of fungal persistence in the cystic fibrosis lung
  Prof P Bowyer, Dr M Bromley, Dr S Gago
Application Deadline: 28 February 2020

Funding Type

PhD Type

Cystic fibrosis (CF) is the most common fatal genetically inherited disease in Caucasian populations. This disease is caused by mutations in the cystic fibrosis transmembrane regulator gene (CFTR) which produces defective ion fluxes and calcium homeostasis in the epithelia.
  Tackling antibiotic resistance: developing a vaccine against gonorrhoea
  Prof J P Derrick, Dr F Hayes
Applications accepted all year round

Funding Type

PhD Type

Gonorrhoea is caused by the Gram-negative bacterium Neisseria gonorrhoeae and is a serious public health problem in developing and developed countries.
  The respiratory metagenome during exacerbations of asthma
  Prof N Papadopoulos, Prof D Robertson, Dr S Megremis
Applications accepted all year round

Funding Type

PhD Type

Asthma is an international pandemic, with 10% or more of the global population having experience asthma symptoms some time in life.
  Biology and genetics of reproduction in filamentous fungi
  Prof P S Dyer
Applications accepted all year round

Funding Type

PhD Type

Filamentous fungi are of importance in the food, industrial and medical sectors and have important roles in the ecology of natural ecosystems.
  Defining how skin fibroblast lineage identity and specificity is maintained ex vivo
  Dr E Rognoni, Dr J Connelly
Application Deadline: 6 March 2020

Funding Type

PhD Type

This is an exciting opportunity for a PhD studentship within the world-renowned William Harvey Research Institute at Barts and The London Medical School and Dentistry (SMD) at Queen Mary University of London (QMUL).
  MRC DTP 4 Year PhD Programme: Bacterial stress sensing and antibiotic action
  Dr U Zachariae, Dr M Bergkessel
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Revealing dynamic and elusive early-mitotic events using state-of-the-art live-cell light sheet imaging
  Dr T Tanaka, Dr M MacDonald
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP iCASE PhD Project: Characterisation of novel niraparib resistance mechanisms in ovarian cancer
  Dr G Smith, Dr M Ferguson
Application Deadline: 13 March 2020

Funding Type

PhD Type

We invite applications from outstanding biological or biomedical sciences graduates for a fully-funded 3.5-year MRC Doctoral Training Programme iCASE PhD studentship, in collaboration with GlaxoSmithKline (GSK), starting in September 2020, based in the Jacqui Wood Cancer Centre in the University of Dundee School of Medicine, Ninewells Hospital & Medical School.
  MSc by Research Programme: Development of tools suited for the in vivo identification and study of protein Complexes in Phytophthora capsici, required for infection.
  Dr E Huitema
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Characterisation of the genotype and phenotype of epithelial cells invaded by the periodontal pathogen Porphyromonas gingivalis.
  Dr S Whawell, Dr G Stafford
Applications accepted all year round

Funding Type

PhD Type

The presence of the Gram negative anaerobe Porphyromonas gingivalis is consistently associated with the more severe forms of periodontal disease and its ability to invade host epithelial cells is thought to be important in the pathogenesis of the disease.
  Warwick’s MRC-Funded DTP in Interdisciplinary Biomedical Research

Funding Type

PhD Type

Fully funded four-year studentships are available for September 2020 to join Warwick's MRC-funded Doctoral Training Partnership (DTP).
  Developing an enzymatic toolbox to make complex modified peptides
  Prof M Jaspars, Dr W Houssen, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

The pharmaceutical industry has identified a major gap in its portfolio. On the one hand, they are excellent at discovering small molecules that act via a lock and key type mechanism.
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