Molecular Biology (membrane) PhD Projects, Programmes & Scholarships

MScR - Computational modelling to investigate the role of membrane microdomains in cell signalling

University of Bristol School of Physiology, Pharmacology & Neuroscience

The dynamic organization of the plasma membrane into specialized cholesterol-rich microdomains plays a crucial role in cellular signalling and the regulation of various biological processes. Read more

Supervisor: Dr RC Corey

Year round applications PhD Research Project Self-Funded PhD Students Only

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Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM

University of Leeds Faculty of Biological Sciences

The BAM complex folds membrane proteins into the outer membrane of Gram-negative bacteria, proteins whose functions are essential for bacterial viability, pathogenicity and virulence. Read more

Supervisors: Prof N A Ranson, Prof S E Radford

Year round applications PhD Research Project Self-Funded PhD Students Only

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How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

The University of Manchester Department of Physics and Astronomy

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Supervisor: Prof J Lu

28 June 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Membrane protein-metabolite interactions important in mitochondrial energy metabolism for burning fat as heat (CRICHTON_U24DTP)

University of East Anglia Norwich Medical School

Primary supervisor - Dr Paul Crichton . Secondary supervisor - Prof. Tom Clarke (UEA) . Mitochondria in our cells harness energy through the breakdown of nutrients to produce ATP through oxidative phosphorylation. Read more

Supervisor: Dr P Crichton

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Crystallization of membrane proteins

Ariel University Chemical Sciences

We aim at developing a SIMPLE-TO-IMPLEMENT & GENERAL crystallization approach for membrane proteins embedded in a micelle of choice. Read more

Supervisor: Dr G Patchornik

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Design and Folding of beta barrel membrane proteins

University of Leeds Faculty of Biological Sciences

The cell walls of Gram negative bacteria are packed with b-barrel outer membrane proteins (OMPs) whose function are essential for bacterial growth and virulence. Read more

Supervisors: Prof S E Radford, Prof D B Brockwell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

Medical Research Council (Cambridge) Mitochondrial Biology Unit

Mitochondria are dynamic organelles forming a specific network by membrane remodeling events according to cellular needs1. Mitochondria contain multiple copies of their own genome, mtDNA, a circular molecule that encodes essential proteins involved in cellular energy production. Read more

Supervisors: Dr Julien Prudent, Prof M Minczuk

16 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

University of Cambridge MRC Mitochondrial Biology Unit

Mitochondria are dynamic organelles forming a specific network by membrane remodeling events according to cellular needs1. Mitochondria contain multiple copies of their own genome, mtDNA, a circular molecule that encodes essential proteins involved in cellular energy production. Read more

Supervisors: Dr Julien Prudent, Prof M Minczuk

16 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health

Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more

Supervisors: Dr A Politis, Dr CP Pliotas

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular dissection of horizontal gene transfer mechanisms in mycobacteria

University of Leicester Molecular and Cell Biology

A fully funded PhD position is available within the lab of Dr Abhinav KV at Leicester Institute of Structural and Chemical Biology (LISCB), University of Leicester, UK to carry out structural studies on large macromolecular machines that undertake horizontal gene transfer (HGT) in mycobacteria. Read more

Supervisors: Dr A Koyamangalath Vadakkepat , Prof J Schwabe

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Discerning the role of metabolic proteins in nucleus

The University of Manchester Faculty of Biology, Medicine and Health

Pancreatic Ductal Adenocarcinoma (PDAC), which develops from cells lining pancreas ducts, represents 95% of all pancreatic cancer cases. Read more

Supervisor: Dr A Latif

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Feel the tension – how does S-acylation of OSCA ion channels regulate responses to environmental change in plants?

University of Dundee School of Life Sciences

Plants, being sessile organisms, must sense and respond to environmental change, such as temperature or drought, without being able to move. Read more

Supervisors: Dr P Hemsley, Prof U Zachariae, Prof M Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Unravelling Alpha-Arrestins: A Promising Strategy to Conquer Candida Infections and Multidrug Resistance

Aberdeen University School of Medicine, Medical Sciences & Nutrition

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Supervisors: Dr T Kubota, Dr R Hatakeyama

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular characterisation of a novel transporter for the atypical antipsychotic clozapine

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Schizophrenia is a severe psychiatric illness affecting about 24 million people worldwide. Schizophrenia can have a devastating effect on a patient’s life and is associated with increased mortality, with life expectancy reduced on average by 15 years compared to that of the general population. Read more

Supervisors: Dr D Dickens, Prof M Pirmohamed

Year round applications PhD Research Project Self-Funded PhD Students Only

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The clinical and therapeutic impact of disialoganglioside GD2 and its synthases on breast cancer

Cardiff University Cardiff School of Medicine

Disialoganglioside GD2 is a plasma membrane member of the large glycosphingolipid family which involves a hydrophobic ceramide bound to a hydrophilic sialic acid-containing glycan chain. Read more

Supervisor: Prof WG Jiang

24 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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Pharmacology of ion channels in human genetic disorders

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Dr J D Lippiat, Dr S Clapcote, Dr K Simmons, Dr S Muench

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR: Endosomal Trafficking Dysfunction in Astrocytes: A Roadmap to Alzheimer’s disease?

University of Bristol School of Physiology, Pharmacology & Neuroscience

Previously thought of as only a support cell for neurons, astrocytes have now been shown to play an essential role in regulating synaptic activity and regulating transmitter uptake and release. Read more

Supervisors: Prof KW Wilkinson, Dr K McMillan, Dr P Banks

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

University of Sussex School of Life Sciences

Research Group: Biochemistry

With 50 million global cases of Alzheimer’s disease (AD) and care costs of 1 trillion UK pounds (expected to triple by 2050), there is a pressing need to slow disease progression, sustain productive lives and reduce costs. Read more

Supervisor: Dr C Prodromou

5 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Using lipid nano-particles to study G-protein-coupled receptors (GPCRs).

Coventry University Centre for Health and Life Sciences

This exciting PhD project in the laboratory of Professor Mark Wheatley, Professor of Biochemical Pharmacology is a joint PhD between Coventry University and Stellenbosch University with the student being registered for a PhD at both universities. Read more

Supervisor: Prof M Wheatley

6 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Engineering extracellular vesicles/exosomes for the treatment of ocular disease

Cardiff University Cardiff School of Optometry & Vision Sciences

Extracellular vesicles, also referred to as exosomes, are membrane‐bound particles containing huge numbers of proteins as well as genetic material in the form of RNA (mRNA and miRNA). Read more

Supervisor: Dr B Mead

5 August 2024 PhD Research Project Self-Funded PhD Students Only

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PhD studentship - Mitochondria and nuclear positioning in skeletal muscle

Newcastle University Translational and Clinical Research Institute

Award Summary. Tuition fees (paid at the home rate) and an annual stipend of £18,622 (2023/2024 rate), with support for research costs. Read more

Supervisor: Dr A Vincent

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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How effective is 3D reconstructed human skin as an alternative to human skin for permeation studies?

University of Bradford Faculty of Life Sciences

The assessment of percutaneous absorption of molecules is a very important step in the evaluation of any transdermal drug delivery system. Read more

Supervisors: Dr X Liu, Dr M Isreb

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Protein secretion landscapes in human immune cells

University of Dundee School of Life Sciences

Roughly one third of the human genome encodes secretory and membrane proteins. Following synthesis in the endoplasmic reticulum (ER), these proteins are captured into transport vesicles for delivery within the cell. Read more

Supervisors: Dr L Miller, Dr A Howden

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic potential of extracellular vesicles from different mesenchymal stem cell subtypes

University of York York Biomedical Research Institute

Human mesenchymal stem/stromal cells (MSCs) are found in adult tissues such as bone marrow and are able to differentiate into bone, cartilage and fat tissues. Read more

Supervisor: Prof P G Genever

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

University of Leicester Molecular and Cell Biology

Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more

Supervisor: Prof S Macip

Year round applications PhD Research Project Self-Funded PhD Students Only

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What is the interrelationship between cell mitosis and cell polarity during apical-basal polarisation of epithelial organs?

The University of Manchester Faculty of Biology, Medicine and Health

My group strives to uncover how mechanics and biochemical signalling work together to shape epithelial organs during development. Read more

Supervisors: Dr C.B Buckley, Dr S Woolner

Year round applications PhD Research Project Self-Funded PhD Students Only

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REGULATION OF BCR SIGNALLING BY DNA DAMAGE RESPONSE AND P53 PROTEIN

Masaryk University Faculty of Medicine

Doctoral study program. Molecular Medicine. Research area. Cancer biology. Consultant. Marek Mraz, MD, Ph.D. We are looking for a motivated PhD student that would like to work on the following project funded by the ERC (European Research Council) Starting grant. Read more

Supervisor: Dr MB Boudny

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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What is the relevance of hormones made in the brain?

University of Reading Department of Biomedical Sciences

Project Overview: . Read more

Supervisors: Dr N Vasudevan, Prof P G Knight

Year round applications PhD Research Project Self-Funded PhD Students Only

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Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Greenwich School of Pharmacy (Medway Campus)

The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more

Supervisors: Dr F Papagiannouli, Dr G Lall

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 33 Molecular Biology (membrane) PhD Projects, Programmes & Scholarships

Molecular Biology (membrane) PhD Projects, Programmes & Scholarships

We have 33 Molecular Biology (membrane) PhD Projects, Programmes & Scholarships

MScR - Computational modelling to investigate the role of membrane microdomains in cell signalling

Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

Membrane protein-metabolite interactions important in mitochondrial energy metabolism for burning fat as heat (CRICHTON_U24DTP)

Crystallization of membrane proteins

Design and Folding of beta barrel membrane proteins

Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

Investigating how mitochondrial dynamics control mtDNA homeostasis and engineering tools to visualise mtDNA molecules

(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Molecular dissection of horizontal gene transfer mechanisms in mycobacteria

Discerning the role of metabolic proteins in nucleus

MSc by Research: Feel the tension – how does S-acylation of OSCA ion channels regulate responses to environmental change in plants?

MSc by Research: Unravelling Alpha-Arrestins: A Promising Strategy to Conquer Candida Infections and Multidrug Resistance

Molecular characterisation of a novel transporter for the atypical antipsychotic clozapine

The clinical and therapeutic impact of disialoganglioside GD2 and its synthases on breast cancer

Pharmacology of ion channels in human genetic disorders

MScR: Endosomal Trafficking Dysfunction in Astrocytes: A Roadmap to Alzheimer’s disease?

Development of LA1011 for high affinity binding to Hsp90 for use towards healthy ageing in patients showing Alzheimer’s symptoms

Using lipid nano-particles to study G-protein-coupled receptors (GPCRs).

Engineering extracellular vesicles/exosomes for the treatment of ocular disease

PhD studentship - Mitochondria and nuclear positioning in skeletal muscle

How effective is 3D reconstructed human skin as an alternative to human skin for permeation studies?

MSc by Research: Protein secretion landscapes in human immune cells

Therapeutic potential of extracellular vesicles from different mesenchymal stem cell subtypes

Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

What is the interrelationship between cell mitosis and cell polarity during apical-basal polarisation of epithelial organs?

REGULATION OF BCR SIGNALLING BY DNA DAMAGE RESPONSE AND P53 PROTEIN

What is the relevance of hormones made in the brain?

Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

We have 33 Molecular Biology (membrane) PhD Projects, Programmes & Scholarships

Molecular Biology (membrane) PhD Projects, Programmes & Scholarships

We have 33 Molecular Biology (membrane) PhD Projects, Programmes & Scholarships

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