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Molecular Biology (natural) PhD Projects, Programs & Scholarships

We have 62 Molecular Biology (natural) PhD Projects, Programs & Scholarships

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  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  FoodBioSystems DTP - Development of different natural biopesticide formulations of plant extracts for control of economically important cereal and grass diseases
  Prof N Magan, Dr G W Griffith, Dr A Medina Vaya, Dr S Palmer
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP. In todays’ cropping systems, crop protection chemicals are used extensively to maintain crop productivity and reduce pest/disease damage.
  Elucidating plant alkaloid biosynthesis
  Dr B R Lichman, Dr W Unsworth
Application Deadline: 30 June 2020

Funding Type

PhD Type

Plants are capable of forming complex natural products from simple starting materials. Many of these natural products are bioactive, but access is limited as they are difficult to synthesise using organic chemistry and are present in small quantities in the natural source.
  Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A O'Neill
Applications accepted all year round

Funding Type

PhD Type

The World Health Organization (WHO) has declared antimicrobial drug resistance one of the greatest problems currently facing human health, and the situation is especially grave in the case of infections caused by bacterial pathogens.
  Natural toxins and their synthetic analogues as tools to study ion channels and as potential drugs and pesticides
  Dr I R Mellor
Applications accepted all year round

Funding Type

PhD Type

The project will use a combination of electrophysiological techniques such as voltage-clamp and patch-clamp with molecular biology and protein expression to understand how natural toxins and their synthetic analogues act on ion channels in the nervous system.
  Fully-funded PhD positions in several natural sciences & engineering disciplines

Funding Type

PhD Type

Join an internationally renowned scientific community with the Hector FellowPhD program. PhD students benefit not only from the experience of the program, but also from the network of Hector Fellows.
  MRC DTP 4 Year PhD Programme: Strategy to identify novel and exploitable anti-malarial drug targets
  Dr S Wyllie, Dr I H Gilbert
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Unravelling the mysteries of retinoid signalling
  Dr E Pohl, Prof J Endicott
Application Deadline: 6 March 2020

Funding Type

PhD Type

Retinoids, such as all-trans-retinoic acid (ATRA), are a class of endogenous molecules derived from Vitamin A. These compounds control a wide range of cellular processes in chordates, including differentiation, proliferation and apoptosis, by binding one or more of related transcriptional receptors in the cell nucleus.
  Defining how skin fibroblast lineage identity and specificity is maintained ex vivo
  Dr E Rognoni, Dr J Connelly
Application Deadline: 6 March 2020

Funding Type

PhD Type

This is an exciting opportunity for a PhD studentship within the world-renowned William Harvey Research Institute at Barts and The London Medical School and Dentistry (SMD) at Queen Mary University of London (QMUL).
  Modelling and optimising the microbial biorefinery process to enhance waste transformation for the promotion of a circular bioeconomy
  Prof J Mcgrath, Dr J Chin
Application Deadline: 31 March 2020

Funding Type

PhD Type

Although microbial communities play major biogeochemical roles in all ecosystems, driving carbon, nitrogen and phosphorus cycling, they remain only crudely represented in existing biogeochemical models of these systems.
  Expanding the Genetic Code of a Synthetic Yeast
  Prof P Cai, Dr A Green
Applications accepted all year round

Funding Type

PhD Type

The proposed project aims to develop an efficient yeast-based protein expression platform with an expanded genetic code. The standard genetic code of natural organisms comprises 20 canonical amino acids.
  Evolving novel and unconventional methods for making precise angstrom capillaries using 2D materials, and exploring molecular separation through them
  Dr R Boya
Applications accepted all year round

Funding Type

PhD Type

Angstrom-scale pores and capillaries have been studied intensively because of their importance in many natural phenomena and use in numerous applications.
  The nanoscale organisation of immune cell surfaces in health and disease
  Prof D Davis
Applications accepted all year round

Funding Type

PhD Type

Super-resolution microscopes, celebrated in the 2014 Nobel Prize for Chemistry, are one of the tools that allow us to study immune cells in unprecedented detail.
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  PhD in Chemical Ecology
  Dr S Campbell
Applications accepted all year round

Funding Type

PhD Type

In response to the near-universal threat of being consumed by insect herbivores, plants have evolved a sophisticated arsenal of chemical defences.
  PhD in the Evolutionary Ecology of Mating Systems
  Dr S Campbell
Applications accepted all year round

Funding Type

PhD Type

Mating and breeding systems govern a wide range of evolutionary processes in plants and animals, including gene flow, genetic variation, and the strength of natural selection.
  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Developing an enzymatic toolbox to make complex modified peptides
  Prof M Jaspars, Dr W Houssen, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

The pharmaceutical industry has identified a major gap in its portfolio. On the one hand, they are excellent at discovering small molecules that act via a lock and key type mechanism.
  SPORES-ON-A-CHIP:Deciphering the responsiveness of environmental spore communities using microfluidic chemostats
  Dr C Stanley
Applications accepted all year round

Funding Type

PhD Type

The Microbiome, Microscopy and Microfluidics Lab at the Department of Bioengineering at Imperial College London – the UK’s leading Bioengineering department – has a fully funded PhD studentship to develop Spores-on-a-Chip microfluidic technology to gain a deeper insight into bacterial spore germination.
  Cell-permeable cyclic peptide library generation for target-based screening
  Prof A Kawamura, Prof M Waring, Dr SL Cobb
Application Deadline: 6 March 2020

Funding Type

PhD Type

Peptides hold enormous promise as chemical tools for selective intervention in biology. They can target chemical space distinct from that of small molecules and their chemical diversity provides high specificity and affinity or target binding.
  Design and synthesis of DNA encoded libraries of unnatural peptides to discover specific chemical probes
  Prof M Waring, Prof A Kawamura, Prof M Noble, Dr SL Cobb
Application Deadline: 6 March 2020

Funding Type

PhD Type

Peptides of allow the rapid identification of protein ligands from huge libraries of genetically encoded peptides, including cyclic peptides.
  Molecular cancer therapeutics activated by radioisotope-generated Cerenkov radiation
  Dr J Knight, Dr R Pal, Dr K Rankin
Application Deadline: 6 March 2020

Funding Type

PhD Type

The beta-particles emitted by certain medical radioisotopes can travel faster than light through the human body. When this happens, a photonic boom - comparable to a sonic boom – releases energy in the form of Cerenkov radiation which has a characteristic blue glow.
  Engineering Cupriavidus Necator H16 to Convert CO2/Waste Stream into Useful Chemicals Using a Synthetic Biology Approach
  Dr TS Wong
Applications accepted all year round

Funding Type

PhD Type

This project falls under the umbrella of carbon capture and utilization (CCU), i.e., to turn a greenhouse gas CO2 into a useful feedstock for chemical syntheses.
  PhD Cancer Genetics - Examining how telomere dysfunction drives the evolution of the cancer genome
  Prof D Baird, Dr K Cleal
Application Deadline: 1 March 2020

Funding Type

PhD Type

Telomeres are structures that cap the ends of eukaryotic chromosomes, preventing the recognition and repair of the natural chromosomal terminus by the DNA damage response (DDR) apparatus.
  Developing New Tools for the Chemical Diversification of Peptide Scaffolds
  Dr SL Cobb, Prof A Kawamura, Prof M Waring
Application Deadline: 6 March 2020

Funding Type

PhD Type

Peptides are useful leads for the development of new drugs against a wide range of diseases. They occupy the chemical space between small molecules and antibodies and as such they can reach or selectively inhibit drug targets that these other molecules cannot.
  PhD position - Structural basis of melanogenesis enzymes
  Dr M Soler-Lopez
Applications accepted all year round

Funding Type

PhD Type

Ref. InnovaXN_17_ESRF. Categorisation. Places of work. - Grenoble, Rhône-Alpes, France. Contract type. Contract, start on 2020-09-07.
  Formation of methyl ketones in distillery fermentations
  Dr A Hill
Application Deadline: 1 March 2020

Funding Type

PhD Type

The influence of wood versus stainless steel washbacks in distillery fermentations has been a long-running interest. The natural microbiological flora present within the distillery and in raw materials has also been widely studied, but a number of questions still remain.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  PhD program in Molecular Inflammation, Molecular Medicine and Advanced Medical Biomarker Research

Funding Type

PhD Type

Projects starting October 1, 2020. Application deadline. March 30, 2020.
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