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Molecular Biology (alzheimer) PhD Projects, Programmes & Scholarships
We have 25 Molecular Biology (alzheimer) PhD Projects, Programmes & Scholarships
We have 25 Molecular Biology (alzheimer) PhD Projects, Programmes & Scholarships
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4-year PhD Studentship: The molecular mechanisms of transcranial ultrasound neuromodulation as a novel therapeutic intervention in neurological disorders
Neural activity follows repetitive, rhythmic patterns, caused by oscillations in membrane potentials or synchronised action potential firing. Read more
Lysozyme encapsulated gold nanoclusters – a new therapeutic agent for Alzheimer’s disease
Alzheimer’s disease (AD) has become a major medical challenge with huge social and economic consequences due to increasing life expectancy. Read more
Understanding how altered GABA signalling in the brain's master clock contributes to circadian rhythm disruption in Alzheimer's disease
Our circadian clock is one of the most important timing systems in our body, ensuring that neuronal activity throughout our CNS is appropriately aligned with our homeostatic, physiological, and behavioural needs across the day. Read more
Generating a disease model for Alzheimer's Disease in non-human primates
Our lab is interested in understanding and treating a devastating neurodegenerative disorder, Alzheimer’s Disease (AD), in particular aspects relating to develop appropriate disease models for AD. Read more
Investigating the timing and causes of vascular dysfunction in Alzheimer’s disease
Rationale. Cerebrovascular damage accelerates and exacerbates cognitive decline and brain damage in Alzheimer's disease (AD)(1, 2). Read more
BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
Research Group:
BBSRC MIBTP
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions. Read more
Synaptic dysfunction in Drosophila models of neurodegenerative diseases
Almost a million of people in the UK suffer from neurodegenerative disorders. Alzheimer’s disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD) are the most common causes of neurodegenerative dementias. Read more
Last chance to apply
Native Mass Spectrometry for the Structural Elucidation of Protein Machines
Research Group:
BBSRC MIBTP
Native mass spectrometry is an expanding structural biology tool that is being used to elucidate the structure of protein complexes and their functions within cells. Read more
Protein degradation-based gene therapies for neurodegenerative disease
Proteins fold like origami into complex three-dimensional shapes. This process can malfunction and result in misfolded proteins that stick together to form large aggregates. Read more
Platelets in health, ageing and disease: new diagnostics and treatments
Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders
Recently, inhibitors of histone deacetylase enzymes (HDACs) have been identified as having potential therapeutic value for a range of neuronal disorders including Alzheimer’s disease, dementia and stroke [1, 2]. Read more
Cell growth signalling in space: How does mTOR kinase communicate with diverse cellular compartments?
PROJECT IN BRIEF. This 4-year PhD project addresses the fundamental question of how individual cells sense and respond to environmental changes. Read more
Last chance to apply
Investigation of an uncharacterised, embryonically lethal gene in immune cell development
This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more
MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation
Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more
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