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We have 42 Molecular Biology (infection biology) PhD Projects, Programmes & Scholarships for Self-funded Students

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Molecular Biology (infection biology) PhD Projects, Programmes & Scholarships for Self-funded Students

We have 42 Molecular Biology (infection biology) PhD Projects, Programmes & Scholarships for Self-funded Students

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Molecular dissection of horizontal gene transfer mechanisms in mycobacteria

University of Leicester Molecular and Cell Biology
A fully funded PhD position is available within the lab of Dr Abhinav KV at Leicester Institute of Structural and Chemical Biology (LISCB), University of Leicester, UK to carry out structural studies on large macromolecular machines that undertake horizontal gene transfer (HGT) in mycobacteria. Read more
 Supervisors: Dr A Koyamangalath Vadakkepat , Prof J Schwabe
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Diagnostics for FMF patients and carrier survival in pandemics

The University of Manchester Faculty of Biology, Medicine and Health
Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more
 Supervisors: Dr P Arkwright, Dr G Lopez-Castejon, Dr J Cavet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bidirectional mobile sRNA signalling in pea-downy mildew interactions

University of Worcester Research School
Plants are constantly being challenged by microbial pathogens and they have evolved the capacity to detect and defend against these incoming microbes. Read more
 Supervisor: Prof M Tor
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

University of York York Biomedical Research Institute
Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more
 Supervisors: Prof F Antson, Dr J Gordeeva, Dr P Bardy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more
 Supervisor: Dr M Soller
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Developing a novel drug screening platform for schistosomes using the free-living flatworm Schmidtea mediterranea

Kingston University Faculty of Health, Science, Social Care and Education
Schistosoma mansoni is one of three major schistosome species that infect over 240 million people across 70 developing countries, with an additional 0.6 billion at risk of infection. Read more
 Supervisor: Dr E Shakir
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health
Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more
 Supervisors: Dr F Errington-Mais, Dr V Jennings
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the Prevalence and Clinical Significance of Genotypic Antibiotic Tolerance Among Important Bacterial Pathogens

University of St Andrews School of Biology
Antibiotic resistance jeopardises our ability to effectively treat bacterial infections, yet it is not the only survival strategy pathogenic bacteria use to evade killing by antibiotics. Read more
 Supervisors: Dr J Hobbs, Dr J pearson, Dr B Parcell
 30 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

The University of Manchester Faculty of Biology, Medicine and Health
Genomic variation that impacts splicing is well established as a cause of genomic disorders, but is almost exclusively limited to protein-coding exons and introns intersecting protein-coding exons. Read more
 Supervisors: Dr J Ellingford, Prof R O'Keefe
 15 June 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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The role of regulatory evolution in phage ecology

The University of Manchester Faculty of Biology, Medicine and Health
The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more
 Supervisors: Dr M Lagator, Dr CI Igler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How does the E5 oncoprotein contribute to human papillomavirus replication and disease?

University of Leeds Faculty of Biological Sciences
The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisors: Dr A Macdonald, Prof A Whitehouse
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Employing molecular virology to investigate hepatitis E virus replication

University of Leeds Faculty of Biological Sciences
This project is available to self funded candidates only. The Herod lab has a broad interest in virus replication, with a particular interest in studying single-stranded positive-sense RNA viruses important for human and animal health. Read more
 Supervisors: Dr M.R. Herod, Prof M Harris
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

University of Bristol School of Biochemistry
Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more
 Supervisor: Prof M D Szczelkun
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MScR: Involvement of astrocytes in neurological manifestations of Long COVID syndrome

University of Bristol School of Physiology, Pharmacology & Neuroscience
A significant fraction of patients affected by Long COVID, long-term consequences following acute SARS-CoV-2 infection, suffer from mental fatigue and cognitive deficits (1-3). Read more
 Supervisor: Prof A Teschemacher
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the effect of promoters on gene expression in novel adeno-associated virus (AAV) producer cell lines.

Medicines and Healthcare Products Regulatory Agency Biotherapeutics and Advanced Therapies Team
We are seeking an enthusiastic candidate to work on an exciting and highly collaborative research project, aimed at identifying and characterising optimal promoter sequences to control expression of AAV genes to engineer novel stable AAV producer cell banks. Read more
 Supervisor: Dr C Kerridge
 19 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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