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University of Birmingham Molecular Biology PhD Projects, Programs & Scholarships

We have 50 University of Birmingham Molecular Biology PhD Projects, Programs & Scholarships

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  Investigating the regulation of DNA replication by ubiquitylation
  Dr A Gambus
Applications accepted all year round

Funding Type

PhD Type

Every dividing cell needs to duplicate its genome perfectly before cell division. Failure to do so can result in cell death or development of mutations leading to cancer.
  Investigating the role of lysine methylation in the DNA damage response.
  Dr M Higgs
Applications accepted all year round

Funding Type

PhD Type

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including haematopoietic abnormalities and developmental disorders as well as cancer.
  Mybl2 in the regulation of cell fate decisions
  Dr P Garcia
Applications accepted all year round

Funding Type

PhD Type

We are interested in the molecular mechanisms regulating cell fate decisions that occur during normal development, somatic reprogramming and cancer.
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  The importance of the DNA damage response in neurodegeneration
  Dr R Tuxworth
Applications accepted all year round

Funding Type

PhD Type

DNA damage occurs in early-stage neurodegenerative diseases. The response of neurons to the damage may contribute to disease progression by inducing senescence, cell-cycle and apoptosis.
  The Role of LIM Domain Only Proteins in Neuroblastoma
  Dr M Hoogenkamp
Applications accepted all year round

Funding Type

PhD Type

Person Specification. An Upper Second Class Honours Degree (or equivalent) in a relevant study or Master’s degree is expected. Prior experience in cell and molecular biology is an advantage.
  Analysing immune responses to metastatic ovarian tumours to identify therapeutic targets
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Investigating how ovarian tumours avoid immune responses in cancer patients
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Understanding the role of Epstein Barr virus in gastric carcinoma
  Dr C Shannon-Lowe, Dr G S Taylor
Applications accepted all year round

Funding Type

PhD Type

BACKGROUND. Epstein Barr virus is a common herpesvirus that is strongly associated with the pathogenesis of at least seven different cancers.
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