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University of Liverpool Molecular Biology PhD Projects, Programs & Scholarships

We have 28 University of Liverpool Molecular Biology PhD Projects, Programs & Scholarships

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  Novel microbial source tracking markers for identification of fecal contaminations in inflow rivers of Taihu Lake
  Dr S Raju, Prof A J McCarthy
Applications accepted all year round

Funding Type

PhD Type

This opportunity is open until position has been filled. The PhD studentship is available for three years subject to satisfactory progress by the student.
  LaNts and laminins in breast cancer
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

The laminins are a family of proteins that make up part of specialised regions of extracellular matrix termed basement membranes.
  LaNts in wound repair, stem cell activation and squamous cell carcinoma
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

The Laminin N terminus proteins (LaNts) are a relatively unstudied protein family that are related to netrins and laminins. To date there are only two publications and one preprint about the LaNt proteins in the literature which means there is a massive potential to do novel, ground breaking research in this area.
  Taking control of cancer-associated splicing switches
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

In cancer, numerous changes to protein expression occur. Some of these are the result of changes to gene transcription or mRNA degradation rates, however, it has increasingly apparent that changes to alternative splicing profile are a key driver of cancer progression.
  Characterization and functional analysis of a novel cancer-associated gene
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

This opportunity will remain open until the position has been filled. In order to identify new candidate cancer-related genes, our lab developed a bioinformatics “guilt-by-association” method to identify and rank genes that are co-expressed with known cancer-related genes.
  Defining the role of NF-𝜅B during embryonic stem cell differentiation
  Dr D Turner, Prof A McArdle
Applications accepted all year round

Funding Type

PhD Type

Mouse Embryonic stem cells (mESCs) are a useful system to probe early development. They can be maintained in a pluripotent state in culture, and differentiated using well-defined protocols to all tissue types of the embryo proper.
  Developing and applying computational methods to understand the genetics of ageing
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is the chief biomedical challenge of the 21st century, yet it remains a major puzzle of biology. Although it is clear that the process of ageing has a strong genetic component, much work remains to elucidate how the genome regulates ageing.
  Targeting ageing: Genes and compounds with pro-longevity, health-preserving effects
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is arguably the major biomedical challenge of the 21st century. In model organisms, the process of ageing can be manipulated by both genetic manipulations and dietary interventions.
  The effect of low protein diet on the development of the musculoskeletal system
  Dr A Vasilaki, Prof MJ Jackson, Dr I Kanakis, Dr K Whysall
Applications accepted all year round

Funding Type

PhD Type

Age-related sarcopenia is characterised by reduction in the number of myofibres and motor neurons and an additional weakening of the remaining fibres, causing reduction in muscle mass and function.
  Uncovering the mechanisms of cryoprotectant toxicity and improving cryopreservation protocols
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Cryopreservation is the process of placing cells, organs or even whole organisms at low temperatures so that they remain in a state of suspended animation and function is preserved.
  Using embryonic stem cell models to determine the importance of post transcriptional gene regulation in the early stages of embryo development
  Dr S Tew, Dr D Turner
Applications accepted all year round

Funding Type

PhD Type

This opportunity will close once a successful applicant has been appointed. This project will examine how regulators of gene expression at the post transcriptional level, affect the very earliest processes of embryo development.
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  Bioengineering of bacterial CO2-concentrating system for improved photosynthesis
  Prof LN Liu, Dr D Canniffe
Applications accepted all year round

Funding Type

PhD Type

The single-cell photosynthetic bacteria, cyanobacteria, account for over 25% of global carbon fixation, thanks for their powerful CO2-concentrating machinery.
  Characterising and repurposing cyanobacterial CO2-fixing organelles for metabolic engineering
  Prof LN Liu, Dr J Hartwell
Applications accepted all year round

Funding Type

PhD Type

Compartmentalisation represents an effective strategy used by cells to enhance their activities. By creating physical barriers and compartments, cells sequester the metabolic pathways from the cellular milieu to allow controls of metabolic flux and toxic diffusion.
  Elucidating Disease Mechanisms using New Approaches to Capture Transient Protein Complexes in the Mitochondria
  Prof L-Y Lian
Applications accepted all year round

Funding Type

PhD Type

The mitochondria is the powerhouse of the cell. Its malfunction is the cause of many diseases, ranging from cancer to heart and neurological diseases, which become more prevalent with age.
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