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University of Oxford Molecular Biology PhD Projects, Programs & Scholarships

We have 31 University of Oxford Molecular Biology PhD Projects, Programs & Scholarships

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  Cross presentation of antigens of recombinant overlapping peptides to optimise vaccines against tumour and infectious diseases
  Dr S Jiang, Dr N Burgess-Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. We have developed a technology to producing overlapping peptides - bacterial expression of an amino acid sequence corresponding to overlapping peptide sequences spanning the length of a protein of interest interspersed with enzymatic cleavage sites.
  Hypoxia links the unfolded proteim response with the DNA damage response
  Prof E Hammond, Prof A Giaccia
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Regions of hypoxia (insufficient oxygen) occur in most if not all solid tumours and are clinically relevant as they correlate with poor patient prognosis and therapy resistance.
  Investigation of the contribution of redox stress to the therapy resistance of cells experiencing cycling oxygen levels
  Prof E Hammond, Dr S Conway
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Hypoxia is a major barrier to successful cancer treatment as the more hypoxic a tumour, the less well patients respond.
  Pre-clinical investigations of POLQ inhibitors
  Dr G Higgins, Prof T Humphrey
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The aim of our research is to improve radiotherapy for cancer patients by making tumour cells more sensitive to radiation without affecting the sensitivity of normal cells.
  Targeting DNA repair to overcome cancer therapy resistance
  Prof P McHugh, Prof T Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. DNA cross-linking drugs and radiotherapy (RT) are used to treat a range of tumours including many hard-to-treat cancers (e.g.
  Translating epigenetic control into novel cancer therapeutics
  Prof N La Thangue, Prof D Kerr
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The retinoblastoma protein pRb is a key tumour suppressor that governs fundamental mechanisms in the G1 to S phase transition of the cell cycle.
  Understanding the impact of hypoxia dynamics on therapeutic response in breast cancer
  Prof E Hammond, Prof H Byrne, Dr S Bohndiek
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. THIS PROJECT HAS BEEN AWARDED FUNDING FROM CANCER RESEARCH UK (EUROPEAN/UK STUDENT ONLY). Hypoxia, resulting from an imbalance between oxygen delivery and consumption, is a common feature of most solid tumours associated clinically with.
  EPSRC Centre for Doctoral Training in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS

Funding Type

PhD Type

Good degree in the Physical or Life Sciences? Interested in biological or medical research? We offer fully-funded PhD places across the Oxford Doctoral Training Centre programmes.
  Academic Endocrine Unit: investigating the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
  Prof R Thakker, Dr K Lines, Dr M Stevenson, Dr K Kooblall
Application Deadline: 24 July 2020

Funding Type

PhD Type

Other Potential Supervisors. Dr Asha Bayliss. The Academic Endocrine Unit investigates the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
  Building the skull – normal and abnormal development
  Prof A Wilkie, Dr S Twigg
Application Deadline: 24 July 2020

Funding Type

PhD Type

Using a combination of patient samples and mouse models, we study the causes and developmental origins of skull malformation. The work ranges from scanning human genome sequences for new mutations, to use of genome editing and single cell transcriptomics to model the developmental causes of these malformations in mice.
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