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University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships
We have 33 University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships
We have 33 University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships
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Determining tumour state using DNA methylation
This project is a collaboration between three research groups. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more
Molecular mechanisms of action and basis of resistance to hypomethylating agents in cancer
The student will be supervised by two supervisors. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more
Single Molecule-based Detection of Mutations in Non-clonal cells
This project is a collaboration between two research groups. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more
Why cell position matters in cancer: role of epigenetic factors
Although cancers are highly mutated, it is factors above and beyond those mutations that allow a tumor to form. These factors include epigenetic gene programs embedded within the cell of origin (Baggiolini, et al, Science 2021). Read more
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Ultrastructural insights into avian herpesvirus-host cell interactions
Marek’s disease virus (MDV) is a major avian alphaherpesvirus associated with Marek’s disease (MD) in poultry characterised by rapid-onset T-cell lymphomas, immunosuppression and paralysis causing annual economic losses of around $2 billion worldwide. Read more
Laboratory of Gene Regulation
Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more
Laboratory of Gene Regulation
Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more
Normal and leukaemic stem/progenitor cell biology and immune responses to blood cancer cells.
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
Normal and leukaemic stem/progenitor cell biology and immune responses to blood cancer cells.
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
Origins of Genotoxic metabolism and the DNA damage response in stem and cancer cells
Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more
Origins of Genotoxic metabolism and the DNA damage response in stem and cancer cells
Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more
Preferential Gq signalling in diabetes: an electrical switch in incretin action and in diabetes progression?
The progression of type 2 diabetes (T2D) involves development of insulin resistance that is frequently associated with obesity and that is initially compensated by increased insulin secretion from pancreatic β-cells. Read more
Realising the therapeutic potential of creatine and homoarginine in heart disease
We study how the heart meets its high and variable energy demands in order to identify novel strategies that may be therapeutically beneficial in disease. Read more
Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more
Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more