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University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships

We have 33 University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships

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Biological Sciences

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Institution

University of Oxford

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We have 33 University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships

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Determining tumour state using DNA methylation

This project is a collaboration between three research groups. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more

Molecular mechanisms of action and basis of resistance to hypomethylating agents in cancer

The student will be supervised by two supervisors. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more

Single Molecule-based Detection of Mutations in Non-clonal cells

This project is a collaboration between two research groups. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more

Why cell position matters in cancer: role of epigenetic factors

Although cancers are highly mutated, it is factors above and beyond those mutations that allow a tumor to form. These factors include epigenetic gene programs embedded within the cell of origin (Baggiolini, et al, Science 2021). Read more
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Ultrastructural insights into avian herpesvirus-host cell interactions

Marek’s disease virus (MDV) is a major avian alphaherpesvirus associated with Marek’s disease (MD) in poultry characterised by rapid-onset T-cell lymphomas, immunosuppression and paralysis causing annual economic losses of around $2 billion worldwide. Read more

Laboratory of Gene Regulation

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more

Laboratory of Gene Regulation

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more

Origins of Genotoxic metabolism and the DNA damage response in stem and cancer cells

Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more

Preferential Gq signalling in diabetes: an electrical switch in incretin action and in diabetes progression?

The progression of type 2 diabetes (T2D) involves development of insulin resistance that is frequently associated with obesity and that is initially compensated by increased insulin secretion from pancreatic β-cells. Read more

Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing

The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more

Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing

The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more

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