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University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships
We have 29 University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships
We have 29 University of Oxford Molecular Biology PhD Projects, Programmes & Scholarships
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Hypoxia signaling pathways and the developmental basis of tumours of the sympatho-adrenal system
Laboratories. . The student will be supervised by. Professor Peter Ratcliffe, Dr Tammie Bishop and Dr Tom Keeley at Ludwig, Oxford. Read more
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Laboratory of Gene Regulation
Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more
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Laboratory of Gene Regulation
Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more
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Normal and leukaemic stem/progenitor cell biology and immune responses to blood cancer cells.
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
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Normal and leukaemic stem/progenitor cell biology and immune responses to blood cancer cells.
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
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Origins of Genotoxic metabolism and the DNA damage response in stem and cancer cells
Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more
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Origins of Genotoxic metabolism and the DNA damage response in stem and cancer cells
Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more
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Preferential Gq signalling in diabetes: an electrical switch in incretin action and in diabetes progression?
The progression of type 2 diabetes (T2D) involves development of insulin resistance that is frequently associated with obesity and that is initially compensated by increased insulin secretion from pancreatic β-cells. Read more
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Realising the therapeutic potential of creatine and homoarginine in heart disease
We study how the heart meets its high and variable energy demands in order to identify novel strategies that may be therapeutically beneficial in disease. Read more
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Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more
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Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more
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Therapeutic opportunities emerging from studies of immune checkpoints
Our focus has been on the cell biology of the T-cell surface. Read more
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Therapeutic opportunities emerging from studies of immune checkpoints
Our focus has been on the cell biology of the T-cell surface. Read more
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Therapeutic targeting of chemokines in inflammation
Protein interactions underlie most biological processes but are challenging to target using small molecule drugs. Many protein interactions are mediated by short-linear-interacting motifs (SLiMs) that range from 3-12 amino acid residues (1, 2). Read more
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Genome Diversification in Cancer and Adaptive Immunity
Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more
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