We have 24 University of Liverpool, MRC DiMeN Doctoral Training Partnership PhD Projects, Programmes & Scholarships
University of Liverpool, MRC DiMeN Doctoral Training Partnership PhD Projects, Programmes & Scholarships
We have 24 University of Liverpool, MRC DiMeN Doctoral Training Partnership PhD Projects, Programmes & Scholarships
MRC DiMeN Doctoral Training Partnership: Cardiovascular function around the clock: harnessing protective circadian mechanisms towards smarter design of novel retinoid therapies and lifestyle interventions
Heart failure (HF) is one of most significant contributors of mortality globally. Whilst some therapeutic options are available, half of the people die within 5 years of diagnosis, and those diagnosed with end-stage heart failure die within a year. Read more
MRC DiMeN Doctoral Training Partnership: Characterization of immunological responses in patients with liver cancer to predict immunotherapy efficacy and immune-related adverse events
Liver cancer, a devastating and incurable cancer has poor patient outcomes largely due to late-stage diagnosis, limited treatment options, and lack of biomarkers for early detection and monitoring of disease progression and treatment response. Read more
MRC DiMeN Doctoral Training Partnership: Development of a biocompatible and bioabsorbable mechanical metamaterial for bone fixation
Orthopaedic screws are essential for treating injuries such as fractures, tendon and ligament injuries, and limb alignment. Therefore, screw failure can significantly impact injury healing. Read more
MRC DiMeN Doctoral Training Partnership: Understanding how diabetes affects retinal cell crosstalk
We are inviting applications for a PhD research project to investigate how diabetes impacts communication between different cell types in the retina, which will enable to unlock new treatments for diabetic eye disease. Read more
MRC DiMeN Doctoral Training Partnership: The role of phosphodiesterases (PDEs) in atrial IP3 signaling: Exploring the potential of utilizing PDEs as therapies for atrial fibrillation
Our project is aligned with MRC and DiMeN Strategy - to tackle major health problems and improve human health. Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia (incidence 1-2%). Read more
MRC DiMeN Doctoral Training Partnership: Dissecting diversity of complement-binding cell surface proteins to enhance leptospiral vaccine efficacy
Making vaccines more broadly protective and easily accessible can only increase uptake, decreasing both global antibiotic use and antimicrobial resistance (AMR). Read more
MRC DiMeN Doctoral Training Partnership: Mitochondrial quality control for a healthy brain
A deterioration in mitochondrial health is linked to normal ageing and several neurodegenerative conditions, including Parkinson’s (PD), Alzheimer’s and Motor Neuron Diseases. Read more
MRC DiMeN Doctoral Training Partnership: The Biting-Edge of AI – Predicting Mosquito Vector Competence for Viruses
Mosquito-borne viruses (arboviruses) pose major global threats to animal and human health, and food security. They are disproportionately prominent in global emerging infectious diseases, currently threaten the UK (e.g., West Nile and Usutu viruses), and will likely continue to increase in their global importance. Read more
MRC DiMeN Doctoral Training Partnership: Regulation of transcription replication conflicts in cancer: mechanism and functional implications in acute myeloid leukemia
This project focuses on the emerging field of transcription-replication conflicts (TRCs) in cancer. In cancer cells, oncogenic transcription is essential for unrestricted cancer cell proliferation, yet it also causes genomic instability during DNA synthesis. Read more
MRC DiMeN Doctoral Training Partnership: Bioengineering a protein nanocage as a novel drug and antigen vaccine delivery platform for cancer therapeutics
Are you passionate about making a difference in cancer treatment? Join our exciting PhD project developing cutting-edge nanotechnology to outsmart cancer!. Read more
MRC DiMeN Doctoral Training Partnership: Signalling systems in Pseudomonas: understanding new routes to prevent Pseudomonas aeruginosa adaptation to the lungs
Background. Cystic Fibrosis (CF) is the most common genetically-inheritable life-threatening disease amongst Caucasians. People with CF are susceptible to chronic lung infections, most commonly caused by the bacterium Pseudomonas aeruginosa (Pa). Read more
MRC DiMeN Doctoral Training Partnership: Migration of Pseudomonas aeruginosa towards antibiotics: mechanisms and consequences
Background. P.aeruginosa is a globally significant “priority” bacterial pathogen (WHO) that causes life-threatening antibiotic-resistant infections. Read more
MRC DiMeN Doctoral Training Partnership: Therapeutics for Middle Eastern Respiratory Syndrome
The overall aim of this project is to develop therapeutic interventions for Middle Eastern respiratory syndrome coronavirus (MERS-CoV). Read more
MRC DiMeN Doctoral Training Partnership: Decoding Shank3: New Insights into neuronal maintenance and neurodegeneration via structural analysis and Drosophila models
As we age, neurons deteriorate. This is often accelerated by mutations in proteins associated with neurological disorders. Shank3 is a key protein in the synapse, where it supports the assembly of postsynaptic density critical for synaptic transmission. Read more
MRC DiMeN Doctoral Training Partnership: Identification of accessible biomarkers reflecting drug stimulation of the NRF2 antioxidant pathway in humans
The transcription factor NRF2 protects cells from oxidative stress and inflammation. It plays a significant role in various diseases (e.g. Read more
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