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University of Dundee, MRC Protein Phosphorylation and Ubiquitylation Unit PhD Projects, Programs & Scholarships

We have 11 University of Dundee, MRC Protein Phosphorylation and Ubiquitylation Unit PhD Projects, Programs & Scholarships

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  Controlling the uncontrollables: How FAM83 proteins regulate the serine/threonine protein kinase CK1 family in cells
  Dr G Sapkota
Application Deadline: 1 December 2019

Funding Type

PhD Type

Members of the CK1 family of kinases, thought to be constitutively active, control a plethora of cellular processes, including cell cycle progression, circadian rhythms, and Wnt signalling, yet how they are controlled to allow such diversity remains poorly understood.
  Deciphering the mechanisms behind DNA repair pathways crucial for preventing cancers
  Prof J Rouse
Application Deadline: 1 December 2019

Funding Type

PhD Type

Our chromosomes are frequently subjected to insults that damage DNA, and if not rectified the resulting DNA lesions can cause genome mutations and human disease.
  Deciphering the ubiquitin codes that regulate protein degradation
  Dr Y Kulathu
Application Deadline: 1 December 2019

Funding Type

PhD Type

Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology.
  Finding the eat-me signals
  Dr I Ganley
Application Deadline: 1 December 2019

Funding Type

PhD Type

The Ganley lab is interested in unravelling the molecular mechanism of autophagy (which literally translates from the Greek meaning to eat oneself).
  Identification and characterization of substrate recognition motifs of Deubiquitinases
  Dr Y Kulathu
Application Deadline: 3 January 2020

Funding Type

PhD Type

PhD position in the Innovative Training Network UBIMOTIF (ESR8). Identification and characterization of substrate recognition motifs of Deubiquitinases.
  Medical Research Council (MRC) Cancer and Genome Integrity PhD Programme 2019/2020

Funding Type

PhD Type

Defects in DNA replication or DNA repair can lead to mutations and other genomic alterations that give rise to cancers, and consequently tumours tend to have a high degree of genome instability.
  Medical Research Council (MRC) Parkinson’s Disease and Neurodegeneration PhD Programme 2019/2020

Funding Type

PhD Type

We are seeking bright and enthusiastic young students to join a new PhD programme at the MRC-PPU dedicated to understanding the cellular mechanisms underlying Parkinson's disease and other neurodegenerative diseases.
  Molecular mechanisms underlying Parkinson's disease
  Prof D Alessi
Application Deadline: 1 December 2019

Funding Type

PhD Type

There is great need for improved understanding of the mechanisms underlying Parkinson’s disease, to help with the development of new drugs that slow or even halt progression of the disease.
  MRC Prize PhD Programme 2019/2020 Protein phosphorylation and ubiquitylation in cancer and neurodegenerative disease

Funding Type

PhD Type

The MRC Protein Phosphorylation and Ubiquitylation Unit is a world-famous centre for the study of cell signaling and how disruption to signaling pathways causes human disease.
  Signalling pathways controlling protein degradation upon stress
  Dr A Rousseau
Application Deadline: 1 December 2019

Funding Type

PhD Type

Increasing evidence shows that alterations and mutations in the UPS give rise to various human diseases, such as cancer and neurodegenerative disorders.
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