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We have 28 Neuroscience (genes) PhD Projects, Programmes & Scholarships

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Neuroscience (genes) PhD Projects, Programmes & Scholarships

We have 28 Neuroscience (genes) PhD Projects, Programmes & Scholarships

MSc by Research: ADP-ribosylation in dementia and motor neuron disease

ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more

Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

Epilepsy is a chronic neurological disease characterised by recurrent spontaneous seizures and cognitive co-morbidities. Current small molecule approaches to treating epilepsy are ineffective in a significant portion of cases, and are associated with substantial adverse effects. Read more

Finding the cause of familial facial (Bell’s) palsy

The facial (VII) cranial nerve controls the muscles of facial expression, supplies taste sensation to parts of the tongue and controls a small muscle connected to the ear drum. Bell’s palsy is the clinical condition in which there is impaired function of the facial nerve, associated with facial muscle weakness. Read more

Understanding how electrical communication can regulate metabolic cycles in bacteria biofilms

Project Overview. A biofilm is a robust form of bacteria colony resistant to antibiotics. They have significant impacts on a multitude of industries impacting health and industrial processes such as in food production and water security. Read more

Targeting ageing and neurodegenerative diseases using the fruit-fly Drosophila melanogaster

In the last 20 years the fruit fly Drosophila melanogaster emerged as a pre-eminent model system for studying changes that occur during both normal and pathological ageing (~75 per cent of the genes that cause disease in humans are also found in the fruit fly!). Read more

Investigating monogenic disorders of the protein synthesis machinery

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more

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