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We have 14 Neuroscience (immune) PhD Projects, Programmes & Scholarships

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Neuroscience (immune) PhD Projects, Programmes & Scholarships

We have 14 Neuroscience (immune) PhD Projects, Programmes & Scholarships

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more

Metabolic modulation of microglial homeostasis and immune response

Microglia are a specialised immune cell found in the central nervous system. They are responsible for maintaining brain homeostasis and play an important role in the early onset and development of neuroinflammatory disorders such as Alzheimer’s disease. Read more

MSc by Research: Nutrient-dependent regulation of microglia function and immune responses

Microglia are constantly sensing the brain environment for metabolic changes, damage and pathogenic invasion. Microglia are highly metabolically active, with activation in response to inflammatory stimulation increasing glycolytic demand. Read more

Exploring Molecular Pathways for Improved Neural Regeneration in Spinal Cord Injury

In the UK, 50,000 people currently live with spinal cord injury (SCI), and an additional 2,500 new cases are reported annually. SCI results in a permanent loss of sensation and movement, serving as a primary cause of paralysis for which effective treatments are currently unavailable. Read more

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
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