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Neuroscience / Neurology (proteomic) PhD Projects, Programs & Scholarships

We have 7 Neuroscience / Neurology (proteomic) PhD Projects, Programs & Scholarships

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  Molecular mechanisms of neuronal ageing in bladder and bowel neurons (ref: SF18/APP/Ranson)
  Dr R Ranson
Applications accepted all year round

Funding Type

PhD Type

Ageing results in a progressive loss of physiological function resulting in a reduced quality of life in the elderly. One of the more prevalent conditions associated with ageing is incontinence-both faecal and urinary.
  Determining brain glycosylation in ageing and Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr C Sutton
Applications accepted all year round

Funding Type

PhD Type

Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism.
  Identifying glucose-dependent mechanisms underlying risk factors for Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr S McLean
Applications accepted all year round

Funding Type

PhD Type

Several risk factors for Alzheimer’s disease including diabetes and midlife obesity are age-dependent and have an obvious metabolic component resulting in impaired glucose metabolism.
  Membrane protein misfolding and disease: quality control pathways
  Dr L Swanton, Prof P Woodman
Applications accepted all year round

Funding Type

PhD Type

Misfolded proteins represent a continuous threat to cell viability, and if allowed to accumulate, can disrupt cellular function and induce cell death.
  Understanding the aetiology of diabetic neuropathy
  Dr N Gardiner, Dr R Unwin
Applications accepted all year round

Funding Type

PhD Type

Diabetic neuropathy is a common secondary complication of diabetes mellitus which affects around 50% of all patients with diabetes - impacting on health, wellbeing and quality of life.
  Molecular dissection of activity-dependent neuronal signalling pathways using quantitative proteomics
  Dr M Collins
Applications accepted all year round

Funding Type

PhD Type

Recent proteomic investigations have identified several thousand proteins in biochemically purified synapses and have uncovered multiprotein complexes essential for synapse function.
  Molecular dissection of protein palmitoylation in neurons
  Dr M Collins
Applications accepted all year round

Funding Type

PhD Type

Palmitoylation (S-acylation), the only known reversible lipid modification of proteins, is an important regulator of protein localisation and function.
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